Rome2Rio

Louisville to Mobile buses

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Trip Overview

The average bus between Louisville and Mobile takes 22h 37m and the fastest bus takes 20h 18m. The bus service runs several times per day from Louisville to Mobile. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

22h 37m
Duration
630 mi
Distance
$132
Average price
Twice daily
Frequency

Louisville to Mobile bus times

Buses run twice daily between Louisville and Mobile. The earliest departure is at 7:25 AM in the morning, and the last departure from Louisville is at 6:30 PM which arrives into Mobile at 1:48 PM. All services require a transfer at Nashville Bus Station and take an average of 22h 37m. The schedules shown below are for the next available departures.

Departing Sunday, November 15, 2026

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    Arrives next day

    Amtrak ThruwayGreyhound USAGreyhound USAThe WAVE25h 23m • 3 changes
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    Arrives next day

    Amtrak ThruwayGreyhound USAGreyhound USAThe WAVE20h 18m • 3 changes

Departing Monday, November 16, 2026

  •  → 

    Arrives next day

    Amtrak ThruwayGreyhound USAGreyhound USAThe WAVE25h 23m • 3 changes
  •  → 

    Arrives next day

    Amtrak ThruwayGreyhound USAGreyhound USAThe WAVE20h 18m • 3 changes

Departing Tuesday, November 17, 2026

  •  → 

    Arrives next day

    Amtrak ThruwayGreyhound USAGreyhound USAThe WAVE25h 23m • 3 changes
  •  → 

    Arrives next day

    Amtrak ThruwayGreyhound USAGreyhound USAThe WAVE20h 18m • 3 changes

Departing Wednesday, November 18, 2026

  •  → 

    Arrives next day

    Amtrak ThruwayGreyhound USAGreyhound USAThe WAVE25h 23m • 3 changes
  •  → 

    Arrives next day

    Amtrak ThruwayGreyhound USAGreyhound USAThe WAVE20h 18m • 3 changes

Departing Thursday, November 19, 2026

  •  → 

    Arrives next day

    Amtrak ThruwayGreyhound USAGreyhound USAThe WAVE25h 23m • 3 changes
  •  → 

    Arrives next day

    Amtrak ThruwayGreyhound USAGreyhound USAThe WAVE20h 18m • 3 changes

Frequently asked questions

Want to know about travelling from Louisville to Mobile? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Louisville to Mobile.ExpandLaunch map view
  • Distance: 629.5 mi
  • Duration: 22h 37m

What companies run services between Louisville, KY, USA and Mobile, AL, USA?

You can take a bus from Louisville, KY to Govt EB at Franklin St via Nashville Bus Station, Montgomery Intermodal Center, Mobile Bus Station, and Govt EB at Greyhound Bus Station in around 13h 55m.

Operators