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Des Moines to Chicago buses

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Trip Overview

The average bus between Des Moines and Chicago takes 8h 13m and the fastest bus takes 7h 5m. The bus service runs several times per day from Des Moines to Chicago. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

8h 13m
Duration
333 mi
Distance
$65
Average price
3 times a day
Frequency

Des Moines to Chicago bus times

Buses run 3 times a day between Des Moines and Chicago. The earliest departure is at 5:30 AM in the morning, and the last departure from Des Moines is at 9:45 AM which arrives into Chicago at 7:45 PM. All services run direct with no transfers required, and take on average 8h 13m. The schedules shown below are for the next available departures.

Frequently asked questions

Want to know about travelling from Des Moines to Chicago? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Des Moines to Chicago.ExpandLaunch map view
  • Distance: 333.2 mi
  • Duration: 8h 13m

What companies run services between Des Moines, IA, USA and Chicago, IL, USA?

Greyhound USA operates a bus from Des Moines to Chicago Bus Station 3 times a day. Tickets cost $50–110 and the journey takes 7h 5m.

Operators