The bus between Des Moines and Chicago takes 8h 5m. There is at least one bus per day from Des Moines to Chicago. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run once daily between Des Moines and Chicago. The earliest departure is at 5:30 AM in the morning, and the last departure from Des Moines is at 5:30 AM which arrives into Chicago at 1:35 PM. All services run direct with no transfers required, and take on average 8h 5m. The schedules shown below are for the next available departures.
Want to know about travelling from Des Moines to Chicago? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
Yes, there is a direct bus departing from Des Moines station and arriving at Chicago station. Services depart once daily, and operate Once daily. The journey takes approximately 8h 5m.
Des Moines to Chicago bus services, operated by Greyhound USA, depart from Des Moines station.
Des Moines to Chicago bus services, operated by Greyhound USA, arrive at Chicago Bus Station.
Book your Des Moines to Chicago bus tickets online with Greyhound USA.
The distance between Des Moines and Chicago is 497.1 km. The road distance is 554 km.
Greyhound USA operates a bus from Des Moines to Chicago Bus Station once daily. Tickets cost $60–110 and the journey takes 8h 5m.