What is the cheapest way to get from Des Moines to Chicago?

The cheapest way to get from Des Moines to Chicago is to bus which costs $40 - $95 and takes 7h 5m.

What is the fastest way to get from Des Moines to Chicago?

The fastest way to get from Des Moines to Chicago is to fly which takes 2h 14m and costs $110 - $650.

Is there a direct bus between Des Moines and Chicago?

Yes, there is a direct bus departing from Des Moines and arriving at Chicago Bus Station station. Services depart three times a day, and operate every day. The journey takes approximately 7h 5m.

How far is it from Des Moines to Chicago?

The distance between Des Moines and Chicago is 324 miles. The road distance is 332.7 miles.

How do I travel from Des Moines to Chicago without a car?

The best way to get from Des Moines to Chicago without a car is to bus which takes 7h 5m and costs $40 - $95.

How long does it take to get from Des Moines to Chicago?

It takes approximately 2h 33m to get from Des Moines to Chicago, including transfers.

Where do I catch the Des Moines to Chicago bus from?

Des Moines to Chicago bus services, operated by Greyhound USA, depart from Des Moines station.

Bus or fly from Des Moines to Chicago?

The best way to get from Des Moines to Chicago is to fly which takes 2h 33m and costs $85 - $450. Alternatively, you can bus, which costs $40 - $95 and takes 7h 5m.

Where does the Des Moines to Chicago bus arrive?

Des Moines to Chicago bus services, operated by Greyhound USA, arrive at Chicago Bus Station.

Can I drive from Des Moines to Chicago?

Yes, the driving distance between Des Moines to Chicago is 333 miles. It takes approximately 5h 33m to drive from Des Moines to Chicago.

How do I get a bus ticket from Des Moines to Chicago?

Book your Des Moines to Chicago bus tickets online with Omio and FlixBus.

Where can I stay near Chicago?

There are 1249+ hotels available in Chicago.

Des Moines to Chicago - 4 ways to travel via plane, bus, and car

There are 4 ways to get from Des Moines to Chicago by plane, bus (Greyhound), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

Fly to Chicago O'Hare International Airport
best
1. Fly from Des Moines (DSM) to Chicago O'Hare International Airport (ORD)plane DSM - ORD
2h 33m
$85–446
Bus (Greyhound)
cheapest
1. Take the bus from Des Moines to Chicago Bus Stationbus Greyhound US0123 / ...
7h 5m
$40–95
Drive 330.7 mi
1. Drive from Des Moines to Chicagocar 330.7 mi
5h 33m
$61–88
Fly to Chicago Midway International Airport
1. Fly from Des Moines (DSM) to Chicago Midway International Airport (MDW)plane DSM - MDW
2h 14m
$110–626

Des Moines to Chicago by bus (Greyhound)

19Weekly Buses

7h 5mAverage Duration

$40Cheapest Price

See schedules

Questions & Answers

Map of how to get from Des Moines to Chicago.

Launch map view

Distance: 322.3 mi
Duration: 2h 33m

What companies run services between Des Moines, IA, USA and Chicago, IL, USA?

American Airlines and United Airlines fly from Des Moines (DSM) to Chicago O'Hare International Airport (ORD) every 4 hours. Alternatively, Greyhound USA operates a bus from Des Moines to Chicago Bus Station 3 times a day. Tickets cost $40–95 and the journey takes 7h 5m.

Airlines

Bus operators

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