Rome2Rio

Guelph to Chicago buses

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Trip Overview

The bus between Guelph and Chicago takes 23h 13m. The bus runs, on average, 2 times per week from Guelph to Chicago. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

23h 13m
Duration
500 mi
Distance
$102
Average price
Twice a week
Frequency

Guelph to Chicago bus times

Buses run twice a week between Guelph and Chicago. The service departs Guelph at 6:52 PM in the evening, which arrives into Chicago at 17:05:00. All services require a transfer at Victoria / Bingemans Centre Dr. and take an average of 23h 13m. The schedules shown below are for the next available departures.

Departing Saturday, November 14, 2026

  •  → 

    Arrives next day

    GO TransitGO TransitFlixbus USAFlixbus USA23h 13m • 3 changes

Departing Sunday, November 15, 2026

  •  → 

    Arrives next day

    GO TransitGO TransitFlixbus USAFlixbus USA23h 13m • 3 changes

Frequently asked questions

Want to know about travelling from Guelph to Chicago? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Guelph to Chicago.ExpandLaunch map view
  • Distance: 499.6 mi
  • Duration: 23h 13m

What companies run services between Guelph, ON, Canada and Chicago, IL, USA?

You can take a bus from Guelph Central GO Bus to Chicago Bus Station via Victoria / Bingemans Centre Dr., Kitchener, and Detroit Bus Station in around 14h 14m.

Operators