The average bus between Depew and Niagara Falls takes 2h 12m and the fastest bus takes 1h 53m. The bus service runs several times per day from Depew to Niagara Falls. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 4 hours between Depew and Niagara Falls. The earliest departure is at 5:53 AM in the morning, and the last departure from Depew is at 7:43 PM which arrives into Niagara Falls at 9:37 PM. All services require a transfer, and take on average 2h 12m. The schedules shown below are for the next available departures.

1h 53m • 1 change

2h 24m • 1 change

2h 24m • 1 change

2h 23m • 1 change

1h 53m • 1 change

2h 24m • 1 change

2h 24m • 1 change

2h 23m • 1 change

1h 53m • 1 change

2h 24m • 1 change

2h 24m • 1 change

2h 23m • 1 change

1h 53m • 1 change

2h 24m • 1 change

2h 24m • 1 change

2h 23m • 1 change

1h 53m • 1 change

2h 24m • 1 change

2h 24m • 1 change

2h 23m • 1 change
Want to know about travelling from Depew to Niagara Falls? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Depew to Niagara Falls. However, there are services departing from Depew station and arriving at Niagara Falls station via Ellicott Street & MTC Static. The journey, including transfers, takes approximately 2h 12m.
Depew to Niagara Falls bus services, operated by NFTA, depart from Broadway & Meridian Street station.
Depew to Niagara Falls bus services, operated by NFTA, arrive at Main Street & Pine Avenue station.
The distance between Depew and Niagara Falls is 36.4 km. The road distance is 68 km.
You can take a bus from Broadway & Meridian Street to Main Street & Pine Avenue via Ellicott Street & MTC Static in around 2h 23m.