The average bus between Comiso and Pisa takes 24h 51m and the fastest bus takes 22h 30m. There is at least one bus per day from Comiso to Pisa. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run once daily between Comiso and Pisa. The earliest departure is at 3:20 PM in the afternoon, and the last departure from Comiso is at 9:50 PM which arrives into Pisa at 1:50 PM. All services require a transfer at Ragusa Bus Terminal and take an average of 24h 51m. The schedules shown below are for the next available departures.
Arrives next day



22h 30m • 3 changes
Arrives next day



23h 45m • 3 changes
Arrives next day



22h 30m • 3 changes
Arrives next day



23h 45m • 3 changes
Arrives next day



22h 30m • 3 changes
Arrives next day



23h 45m • 3 changes
Want to know about travelling from Comiso to Pisa? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Comiso to Pisa. However, there are services departing from Comiso station and arriving at Pisa station via Catania Via Archimede. The journey, including transfers, takes approximately 24h 51m.
Comiso to Pisa bus services, operated by Azienda Siciliana Trasporti, depart from Ragusa Bus Terminal station.
Comiso to Pisa bus services, operated by Azienda Siciliana Trasporti, arrive at Pisa station.
The distance between Comiso and Pisa is 831.5 km. The road distance is 1,256 km.
You can take a bus from Comiso to Pisa via Ragusa Bus Terminal, Catania Via Archimede, Catania, and Florence Villa Constanza Bus Station in around 20h 35m.