Rome2Rio

Comiso to Florence buses

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Trip Overview

The average bus between Comiso and Florence takes 22h 57m and the fastest bus takes 17h 25m. The bus service runs several times per day from Comiso to Florence. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

22h 57m
Duration
1,178 km
Distance
€129
Average price
Twice daily
Frequency

Comiso to Florence bus times

Buses run twice daily between Comiso and Florence. The earliest departure is at 3:20 PM in the afternoon, and the last departure from Comiso is at 9:50 PM which arrives into Florence at 1:45 AM. All services require a transfer at Ragusa Bus Terminal and take an average of 22h 57m. The schedules shown below are for the next available departures.

Departing Sunday, November 15, 2026

  •  → 

    Arrives +2 days

    Azienda Siciliana TrasportiInterbusFlixBus27h 55m • 2 changes

Departing Monday, November 16, 2026

  •  → 

    Arrives next day

    Azienda Siciliana TrasportiInterbusFlixBus17h 25m • 2 changes
  •  → 

    Arrives +2 days

    Azienda Siciliana TrasportiInterbusFlixBus27h 55m • 2 changes

Departing Tuesday, November 17, 2026

  •  → 

    Arrives next day

    Azienda Siciliana TrasportiInterbusFlixBus17h 25m • 2 changes
  •  → 

    Arrives +2 days

    Azienda Siciliana TrasportiInterbusFlixBus27h 55m • 2 changes

Departing Wednesday, November 18, 2026

  •  → 

    Arrives next day

    Azienda Siciliana TrasportiInterbusFlixBus17h 25m • 2 changes
  •  → 

    Arrives +2 days

    Azienda Siciliana TrasportiInterbusFlixBus27h 55m • 2 changes

Departing Thursday, November 19, 2026

  •  → 

    Arrives next day

    Azienda Siciliana TrasportiInterbusFlixBus17h 25m • 2 changes
  •  → 

    Arrives +2 days

    Azienda Siciliana TrasportiInterbusFlixBus27h 55m • 2 changes

Departing Friday, November 20, 2026

  •  → 

    Arrives next day

    Azienda Siciliana TrasportiInterbusFlixBus17h 25m • 2 changes
  •  → 

    Arrives +2 days

    Azienda Siciliana TrasportiInterbusFlixBus31h 25m • 2 changes

Departing Saturday, November 21, 2026

  •  → 

    Arrives next day

    Azienda Siciliana TrasportiInterbusFlixBus17h 25m • 2 changes

Frequently asked questions

Want to know about travelling from Comiso to Florence? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Comiso to Florence.ExpandLaunch map view
  • Distance: 1,178.4 km
  • Duration: 22h 57m

What companies run services between Comiso, Italy and Florence, Italy?

You can take a bus from Comiso to Florence Villa Constanza Bus Station via Ragusa Bus Terminal, Aeroporto Vincenzo Bellini/Fontanarossa, and Catania Airport in around 19h.

Operators