Rome2Rio

Comiso to Brindisi buses

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Trip Overview

The bus between Comiso and Brindisi takes 14h. There is at least one bus per day from Comiso to Brindisi. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

14h
Duration
761 km
Distance
€62
Average price
Once daily
Frequency

Comiso to Brindisi bus times

Buses run once daily between Comiso and Brindisi. The service departs Comiso at 2:45 PM in the afternoon, which arrives into Brindisi at 04:45:00. All services require a transfer, and take on average 14h. The schedules shown below are for the next available departures.

Departing Tuesday, November 10, 2026

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    Arrives next day

    FlixBusSAIS trasporti S.p.A. - Autolinee Giamporcaro14h • 1 change

Departing Wednesday, November 11, 2026

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    Arrives next day

    FlixBusSAIS trasporti S.p.A. - Autolinee Giamporcaro14h • 1 change

Departing Thursday, November 12, 2026

  •  → 

    Arrives next day

    FlixBusSAIS trasporti S.p.A. - Autolinee Giamporcaro14h • 1 change

Departing Friday, November 13, 2026

  •  → 

    Arrives next day

    FlixBusSAIS trasporti S.p.A. - Autolinee Giamporcaro14h • 1 change

Departing Saturday, November 14, 2026

  •  → 

    Arrives next day

    FlixBusSAIS trasporti S.p.A. - Autolinee Giamporcaro14h • 1 change

Departing Sunday, November 15, 2026

  •  → 

    Arrives next day

    FlixBusSAIS trasporti S.p.A. - Autolinee Giamporcaro14h • 1 change

Departing Monday, November 16, 2026

  •  → 

    Arrives next day

    FlixBusSAIS trasporti S.p.A. - Autolinee Giamporcaro14h • 1 change

Frequently asked questions

Want to know about travelling from Comiso to Brindisi? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Comiso to Brindisi.ExpandLaunch map view
  • Distance: 760.8 km
  • Duration: 14h

What companies run services between Comiso, Italy and Brindisi, Italy?

You can take a bus from Comiso to Brindisi via Siracusa - Corso Umberto in around 12h 45m.

Operators