The average bus between Comiso and Sicily takes 3h 57m and the fastest bus takes 3h 40m. The bus service runs several times per day from Comiso to Sicily. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Comiso and Sicily. The earliest departure is at 5:55 AM in the morning, and the last departure from Comiso is at 6:15 PM which arrives into Sicily at 9:55 PM. All services require a transfer, and take on average 3h 57m. The schedules shown below are for the next available departures.

4h 7m • 1 change

4h 14m • 1 change

4h 18m • 1 change

3h 45m • 1 change

3h 58m • 1 change

3h 58m • 1 change

3h 58m • 1 change

3h 40m • 1 change
Want to know about travelling from Comiso to Sicily? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Comiso to Sicily. However, there are services departing from Comiso station and arriving at Sicily station via Palermo. The journey, including transfers, takes approximately 3h 57m.
Comiso to Sicily bus services, operated by Azienda Siciliana Trasporti, depart from Comiso station.
Comiso to Sicily bus services, operated by Azienda Siciliana Trasporti, arrive at Palermo station.
The distance between Comiso and Sicily is 81.5 km. The road distance is 220 km.
Azienda Siciliana Trasporti operates a bus from Comiso to Palermo 3 times a day, and the journey takes 3h 35m.