The average bus between Comiso and Messina takes 7h and the fastest bus takes 4h 20m. The bus service runs several times per day from Comiso to Messina. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 4 times a day between Comiso and Messina. The earliest departure is at 7:00 AM in the morning, and the last departure from Comiso is at 9:50 PM which arrives into Messina at 4:05 PM. All services require a transfer at Ragusa Bus Terminal and take an average of 7h. The schedules shown below are for the next available departures.


4h 25m • 2 changes


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7h 5m • 2 changes


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7h 5m • 2 changes
Want to know about travelling from Comiso to Messina? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Comiso to Messina. However, there are services departing from Comiso station and arriving at Messina station via Catania Via Archimede. The journey, including transfers, takes approximately 7h.
Comiso to Messina bus services, operated by Azienda Siciliana Trasporti, depart from Ragusa Bus Terminal station.
Comiso to Messina bus services, operated by Azienda Siciliana Trasporti, arrive at Messina station.
The distance between Comiso and Messina is 161.6 km. The road distance is 208 km.
You can take a bus from Comiso to Messina via Ragusa Bus Terminal, Catania Via Archimede, and Catania in around 5h 40m.