The average bus between Cincinnati and St. Louis takes 10h 29m and the fastest bus takes 9h 10m. The bus service runs several times per day from Cincinnati to St. Louis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Cincinnati and St. Louis. The earliest departure is at 7:00 AM in the morning, and the last departure from Cincinnati is at 1:40 PM which arrives into St. Louis at 11:15 PM. All services require a transfer at Indianapolis and take an average of 10h 29m. The schedules shown below are for the next available departures.
Want to know about travelling from Cincinnati to St. Louis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Cincinnati to St. Louis. However, there are services departing from Cincinnati station and arriving at St. Louis station via Indianapolis. The journey, including transfers, takes approximately 10h 29m.
Cincinnati to St. Louis bus services, operated by Flixbus USA, depart from Cincinnati station.
Cincinnati to St. Louis bus services, operated by Flixbus USA, arrive at St Louis Bus Station.
Book your Cincinnati to St. Louis bus tickets online with Flixbus USA and Greyhound USA.
The distance between Cincinnati and St. Louis is 495 km. The road distance is 568 km.
You can take a bus from Cincinnati to St Louis Bus Station via Indianapolis and Indianapolis Union Station in around 7h 24m.
