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There are 6 ways to get from Chicago to St Louis by train, bus, car or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended

Train

  1. Take the train from Chicago Union Station to St. Louis

Cheapest

Bus

  1. Take the bus from Chicago to St Louis

Drive

  1. Drive from Chicago to St Louis

Fly from Chicago O'Hare

  1. Fly from Chicago O'Hare (ORD) to St. Louis (STL)

Fly from Chicago Midway

  1. Fly from Chicago Midway (MDW) to St. Louis (STL)

Train to Milwaukee, fly

  1. Take the train from Chicago Union Station to Milwaukee
  2. Fly from Milwaukee (MKE) to St. Louis (STL)

Chicago to St Louis by train

The train journey time between Chicago and St Louis is around 5h 30m and covers a distance of around 282 miles. The fastest train normally takes 5h 20m. Operated by Amtrak, the Chicago to St Louis train service departs from Chicago Union Station and arrives in St. Louis. Typically 38 trains run weekly, although weekend and holiday schedules can vary so check in advance.

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Train route information

Average train time:
5h 30m
Fastest train time:
5h 20m
Train distance:
282 miles
Trains per week:
38
Cheapest price:
$40
Carbon emissions:
23 kg CO2

First and last trains

First train departs at:
07:00
Last train departs at:
19:00

The schedules shown below are for the next available departures.

Chicago to St Louis train schedules

Questions & Answers

The cheapest way to get from Chicago to St Louis is to drive which costs $29 - $45 and takes 4h 58m.

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The fastest way to get from Chicago to St Louis is to fly. Taking this option will cost $130 - $2,900 and takes 3h 21m.

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Yes, there is a direct bus departing from Chicago and arriving at St Louis. Services depart once daily, and operate every day. The journey takes approximately 6h 40m.

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Yes, there is a direct train departing from Chicago Union Station station and arriving at St. Louis. Services depart five times a day, and operate every day. The journey takes approximately 5h 30m.

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The distance between Chicago and St Louis is 264 miles. The road distance is 298.2 miles.

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The best way to get from Chicago to St Louis without a car is to train which takes 5h 30m and costs $40 - $60.

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The train from Chicago Union Station to St. Louis takes 5h 30m including transfers and departs five times a day.

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Chicago to St Louis bus services, operated by Greyhound USA, depart from Chicago station.

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Chicago to St Louis train services, operated by Amtrak, depart from Chicago Union Station.

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The best way to get from Chicago to St Louis is to train which takes 5h 30m and costs $40 - $60. Alternatively, you can bus, which costs $35 - $55 and takes 6h 40m, you could also fly, which costs $40 - $170 and takes 3h 33m.

Mode details

Map of how to get from Chicago to St Louis.
Launch map view
  • Distance: 263.7 miles
  • Duration: 5h 30m

What companies run services between Chicago, IL, USA and St Louis, MO, USA?

Amtrak operates a train from Chicago Union Station to St. Louis 5 times a day. Tickets cost $40 - $60 and the journey takes 5h 30m. Alternatively, Greyhound USA operates a bus from Chicago to St Louis once daily. Tickets cost $35 - $55 and the journey takes 6h 40m.

Airlines
American Airlines
Website
aa.com
Flights from Chicago O'Hare to St. Louis
Ave. Duration
1h 17m
When
Every day
Estimated price
$95 - $300
Flights from Chicago O'Hare to St. Louis via Quincy
Ave. Duration
2h 58m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$120 - $320
Flights from Milwaukee to St. Louis via Chicago O'Hare
Ave. Duration
3h 25m
When
Every day
Estimated price
$100 - $270
Southwest Airlines
Website
southwest.com
Flights from Chicago Midway to St. Louis
Ave. Duration
1h 10m
When
Every day
Estimated price
$140 - $400
Flights from Milwaukee to St. Louis
Ave. Duration
1h 20m
When
Every day
Estimated price
$130 - $400
United Airlines
Website
united.com
Flights from Chicago O'Hare to St. Louis
Ave. Duration
1h 24m
When
Every day
Estimated price
$95 - $350
Flights from Milwaukee to St. Louis via Chicago O'Hare
Ave. Duration
3h 33m
When
Every day
Estimated price
$85 - $380
Cape Air
Website
capeair.com
Flights from Chicago O'Hare to St. Louis via Quincy
Ave. Duration
2h 58m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$120 - $320
Frontier Airlines
Website
flyfrontier.com
Flights from Chicago O'Hare to St. Louis
Ave. Duration
1h 19m
When
Monday and Friday
Estimated price
$35 - $430
GoJet Airlines
Website
gojetairlines.com
Flights from Chicago O'Hare to St. Louis
Ave. Duration
1h 22m
When
Every day
Estimated price
$14 - $280
Train operators
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 800-872-7245
Website
amtrak.com
Train from Chicago Union Station to St. Louis
Ave. Duration
5h 30m
Frequency
5 times a day
Estimated price
$40 - $60
Schedules at
amtrak.com
Book at
amtrak.com
Coach Seat
$40 - $60
Premium
$210 - $300
Flexi Coach Seat
$75 - $110
Business Seat
$75 - $110
Train from Chicago Union Station to Milwaukee
Ave. Duration
1h 29m
Frequency
Every 4 hours
Estimated price
$27 - $40
Schedules at
amtrak.com
Book at
amtrak.com
Coach Seat
$27 - $40
Premium
$180 - $260
Flexi Coach Seat
$40 - $60
Business Seat
$35 - $55
Bus operators
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Chicago to St Louis
Ave. Duration
6h 40m
Frequency
Once daily
Estimated price
$35 - $55
Website
greyhound.com
Economy
$35 - $55
Flexible
$60 - $90

Want to know more about travelling around United States

Rome2rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

More Questions & Answers

The quickest flight from Chicago O'Hare Airport to St. Louis Airport is the direct flight which takes 1h 10m.

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Chicago to St Louis bus services, operated by Greyhound USA, arrive at St Louis station.

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Chicago to St Louis train services, operated by Amtrak, arrive at St. Louis station.

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Yes, the driving distance between Chicago to St Louis is 298 miles. It takes approximately 4h 58m to drive from Chicago to St Louis.

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Frontier Airlines, GoJet Airlines, United Airlines and two other airlines offer flights from Chicago O'Hare Airport to St. Louis Airport.

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Book your Chicago to St Louis train tickets online with Omio.

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Book your Chicago to St Louis bus tickets online with Omio and Busbud.

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There are 175+ hotels available in St Louis. Prices start at $100 USD per night.

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The best way to get from Chicago to Chicago O'Hare Airport is to subway which takes 42 min and costs $1 - $5.

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