Travel from Chicago to St-Louis

Train, bus or fly from Chicago to St. Louis?

Southwest Airlines flies from Chicago to St. Louis every 4 hours. Alternatively, Amtrak operates a train from Chicago to St. Louis every 4 hours. Tickets cost $50 - $130 and the journey takes 5 h 30 min.

Book transport from Chicago to St. Louis

Travel Guides

Want to know more about US trains?Rome2rio has everything you need to know about travelling with Amtrak
Need to know: GreyhoundRome2rio’s guide on the bus operator has all the information you need

How to get from Chicago to St. Louis

From Adams/Wabash subway to Chicago Midway airport, fly to St. Louis airport, then train to St. Louis. 3 h 7 min $175. From Jackson-Blue subway to Chicago O'Hare airport, fly to St. Louis airport, then train to St. Louis. 3 h 28 min $106. From Chicago Union Station Amtrak train to St. Louis Gateway Station Amtrak. 5 h 30 min $92. From Chicago, IL bus to St. Louis, MO. 5 h 45 min $35. From Chicago drive to St. Louis. 4 h 53 min $35.

Operators from Chicago to St. Louis

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  1. Here are 5 options to get from
    Chicago to St. Louis:

    1. Trip:
      1 Fly from Chicago Midway
      • One-Way approx: USD $124 - $306
      • Duration: 3 h 7 min
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      • Trip:
        1 Fly from Chicago Midway
        • One-Way approx: USD $124 - $306
        • Duration: 3 h 7 min
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    2. Trip:
      2 Fly from Chicago O'Hare
      • One-Way approx: USD $89 - $247
      • Duration: 3 h 28 min
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      • Trip:
        2 Fly from Chicago O'Hare
        • One-Way approx: USD $89 - $247
        • Duration: 3 h 28 min
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    3. Trip:
      3 Train
      • One-Way approx: USD $50 - $130
      • Duration: 5 h 30 min
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      • Trip:
        3 Train
        • One-Way approx: USD $50 - $130
        • Duration: 5 h 30 min
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    4. Trip:
      4 Bus
      • One-Way approx: USD $25 - $85
      • Duration: 5 h 45 min
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      • Trip:
        4 Bus
        • One-Way approx: USD $25 - $85
        • Duration: 5 h 45 min
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    5. Trip:
      5 Drive
      • One-Way approx: USD $29 - $45
      • Duration: 4 h 53 min
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      • Trip:
        5 Drive
        • One-Way approx: USD $29 - $45
        • Duration: 4 h 53 min
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