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Buffalo to St. Louis buses

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Trip Overview

The bus between Buffalo and St. Louis takes 18h 35m. The bus runs, on average, 6 times per week from Buffalo to St. Louis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

18h 35m
Duration
811 mi
Distance
$157
Average price
6 times a week
Frequency

Buffalo to St. Louis bus times

Buses run 6 times a week between Buffalo and St. Louis. The service departs Buffalo at 2:20 PM in the afternoon, which arrives into St. Louis at 07:55:00. All services require a transfer at Akron and take an average of 18h 35m. The schedules shown below are for the next available departures.

Departing Friday, October 23, 2026

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    Arrives next day

    Barons BusBarons BusGreyhound USA18h 35m • 2 changes

Departing Saturday, October 24, 2026

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    Arrives next day

    Barons BusBarons BusGreyhound USA18h 35m • 2 changes

Departing Sunday, October 25, 2026

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    Arrives next day

    Barons BusBarons BusGreyhound USA18h 35m • 2 changes

Departing Monday, October 26, 2026

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    Arrives next day

    Barons BusBarons BusGreyhound USA18h 35m • 2 changes

Departing Tuesday, October 27, 2026

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    Arrives next day

    Barons BusBarons BusGreyhound USA18h 35m • 2 changes

Departing Wednesday, October 28, 2026

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    Arrives next day

    Barons BusBarons BusGreyhound USA18h 35m • 2 changes

Frequently asked questions

Want to know about travelling from Buffalo to St. Louis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Buffalo to St. Louis.ExpandLaunch map view
  • Distance: 811.4 mi
  • Duration: 18h 35m

What companies run services between Buffalo, NY, USA and St. Louis, MO, USA?

You can take a bus from Buffalo to St Louis Bus Station via Akron and Cambridge, OH in around 18h 5m.

Operators