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The train between Buffalo and St. Louis takes 32h. The train runs, on average, 6 times per week from Buffalo to St. Louis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 6 times a week between Buffalo and St. Louis. The service departs Buffalo at 12:25 PM in the afternoon, which arrives into St. Louis at 19:25:00. All services require a transfer at Buffalo Depew Station and take an average of 32h. The schedules shown below are for the next available departures.
Want to know about travelling from Buffalo to St. Louis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Buffalo to St. Louis. However, there are services departing from Buffalo Depew Station and arriving at St. Louis station via Chicago Union Station. The journey, including transfers, takes approximately 32h.
Buffalo to St. Louis train services, operated by Amtrak, depart from Buffalo Depew Station.
Buffalo to St. Louis train services, operated by Amtrak, arrive at St. Louis station.
Book your Buffalo to St. Louis train tickets online with Omio.
The distance between Buffalo and St. Louis is 1063.3 km. The road distance is 1186 km.
You can take a train from Buffalo to St. Louis via Buffalo Depew Station and Chicago Union Station in around 17h 36m.
