The average bus between Buffalo and Middlesex takes 10h 42m and the fastest bus takes 9h 56m. The bus service runs several times per day from Buffalo to Middlesex. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 4 times a day between Buffalo and Middlesex. The earliest departure is at 12:55 AM at night, and the last departure from Buffalo is at 8:45 PM which arrives into Middlesex at 9:46 AM. All services require a transfer, and take on average 10h 42m. The schedules shown below are for the next available departures.
Arrives next day

10h 18m • 1 change
Arrives next day

11h 15m • 1 change

10h 9m • 1 change

10h 34m • 1 change
Arrives next day

10h 18m • 1 change
Arrives next day

11h 15m • 1 change

10h 9m • 1 change

10h 34m • 1 change
Arrives next day

10h 18m • 1 change
Arrives next day

11h 15m • 1 change

10h 9m • 1 change

10h 34m • 1 change
Arrives next day

10h 18m • 1 change
Arrives next day

11h 15m • 1 change

10h 9m • 1 change

10h 34m • 1 change
Arrives next day

10h 18m • 1 change
Arrives next day

13h 5m • 1 change
Want to know about travelling from Buffalo to Middlesex? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Buffalo to Middlesex. However, there are services departing from Buffalo station and arriving at Middlesex station via Port Authority Bus Terminal. The journey, including transfers, takes approximately 10h 42m.
Buffalo to Middlesex bus services, operated by Greyhound USA, depart from Buffalo station.
Buffalo to Middlesex bus services, operated by Greyhound USA, arrive at Boundbrook Rd At John F. Kennedy Dr station.
The distance between Buffalo and Middlesex is 445.5 km. The road distance is 810 km.
You can take a bus from Buffalo to Boundbrook Rd At John F. Kennedy Dr via Port Authority Bus Terminal in around 10h 21m.