Rome2Rio

How to get fromBuffalo to Middlesexby plane, train, bus (Greyhound), train (Amtrak), car, bus, or bus (Flixbus)

Find Transport to Middlesex

See all options

There are 10 ways to get from Buffalo to Middlesex by plane, train, bus (Greyhound), train (Amtrak), car, bus, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Buffalo Niagara International Airport to Newark Liberty International Airport, train

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to Newark Liberty International Airport (EWR)plane plane BUF - EWR
    2. Take the train from Newark Penn Station to Dunellentrain train
    4h 43m
    $65–430

  2. Drive 338.5 mi

    cheapest
    1. Drive from Buffalo to Middlesexcar car 338.5 mi
    7h 4m
    $62–90

  3. Bus

    1. Take the bus from Buffalo to Port Authority Bus Terminalbus bus Greyhound US0205 / ...
    2. Take the bus from Port Authority Bus Terminal to Boundbrook Rd At John F. Kennedy Drbus bus 114
    10h 16m
    $67–283

  4. Train (Amtrak)

    1. Take the train from Buffalo to Ny Moynihan Train Hall At Penn Stationtrain train Empire Service / ...
    10h 30m
    $142–842

  5. Fly Buffalo Niagara International Airport to Laguardia Airport, train

    1. Fly from Buffalo Niagara International Airport (BUF) to Laguardia Airport (LGA)plane plane BUF - LGA
    2. Take the train from Newark Penn Station to Dunellentrain train
    5h 31m
    $109–712

  6. Fly Buffalo Niagara International Airport to John F. Kennedy International Airport, train

    1. Fly from Buffalo Niagara International Airport (BUF) to John F. Kennedy International Airport (JFK)plane plane BUF - JFK
    2. Take the train from Newark Penn Station to Dunellentrain train
    5h 21m
    $80–455

  7. Bus to Rochester, fly to Newark Liberty International Airport

    1. Take the bus from Buffalo to Rochester Bus Stopbus bus
    2. Fly from Rochester (ROC) to Newark Liberty International Airport (EWR)plane plane ROC - EWR
    6h 8m
    $322–916

  8. Fly Buffalo Niagara International Airport to Philadelphia International Airport, train

    1. Fly from Buffalo Niagara International Airport (BUF) to Philadelphia International Airport (PHL)plane plane BUF - PHL
    2. Take the train from 30th Street Station to Newark Penn Stationtrain train
    6h 17m
    $140–1,398

  9. Bus via New York

    1. Take the bus from Buffalo to New York Midtownbus bus FlixBus 2686 / ...
    2. Take the bus from Port Authority Bus Terminal to Boundbrook Rd At John F. Kennedy Drbus bus 114
    10h 47m
    $67–129

  10. Train, bus

    1. Take the train from Buffalo to New York Penn Stationtrain train VIA Rail
    2. Take the bus from Port Authority Bus Terminal to Boundbrook Rd At John F. Kennedy Drbus bus 114
    12h 25m
    $88–141

Buffalo to Middlesex by bus

Calendar52Weekly Buses
Duration10h 16mAverage Duration
Ticket$67Cheapest Price
See schedules

Questions & Answers

Map of how to get from Buffalo to Middlesex.ExpandLaunch map view
  • Distance: 319.1 mi
  • Duration: 4h 43m

What companies run services between Buffalo, NY, USA and Middlesex, NJ, USA?

You can take a bus from Buffalo to Boundbrook Rd At John F. Kennedy Dr via Port Authority Bus Terminal in around 10h 16m. Alternatively, Amtrak operates a train from Buffalo to Ny Moynihan Train Hall At Penn Station 3 times a day. Tickets cost $130–280 and the journey takes 8h 17m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers