Rome2Rio

Buffalo to Myrtle Beach buses

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Trip Overview

The bus between Buffalo and Myrtle Beach takes 25h 5m. The bus runs, on average, 4 times per week from Buffalo to Myrtle Beach. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

25h 5m
Duration
1,097 mi
Distance
$216
Average price
4 times a week
Frequency

Buffalo to Myrtle Beach bus times

Buses run 4 times a week between Buffalo and Myrtle Beach. The service departs Buffalo at 10:30 AM in the morning, which arrives into Myrtle Beach at 11:35:00. All services require a transfer at Newark Penn Station and take an average of 25h 5m. The schedules shown below are for the next available departures.

Departing Friday, November 13, 2026

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    Arrives next day

    Flixbus USAFlixbus USAGreyhound USA25h 5m • 2 changes

Departing Saturday, November 14, 2026

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    Arrives next day

    Flixbus USAFlixbus USAGreyhound USA25h 5m • 2 changes

Departing Monday, November 16, 2026

  •  → 

    Arrives next day

    Flixbus USAFlixbus USAGreyhound USA25h 5m • 2 changes

Departing Tuesday, November 17, 2026

  •  → 

    Arrives next day

    Flixbus USAFlixbus USAGreyhound USA25h 5m • 2 changes

Frequently asked questions

Want to know about travelling from Buffalo to Myrtle Beach? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Buffalo to Myrtle Beach.ExpandLaunch map view
  • Distance: 1,097.1 mi
  • Duration: 25h 5m

What companies run services between Buffalo, NY, USA and Myrtle Beach, SC, USA?

You can take a bus from Buffalo to Myrtle Beach Bus Station via Newark Penn Station and Fayetteville Bus Station in around 23h 15m.

Operators