The average bus between Appleton and St. Louis takes 15h 15m and the fastest bus takes 13h 50m. The bus runs, on average, 5 times per week from Appleton to St. Louis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 5 times a week between Appleton and St. Louis. The earliest departure is at 9:30 AM in the morning, and the last departure from Appleton is at 9:30 AM which arrives into St. Louis at 11:20 PM. All services require a transfer, and take on average 15h 15m. The schedules shown below are for the next available departures.
Want to know about travelling from Appleton to St. Louis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Appleton to St. Louis. However, there are services departing from Appleton station and arriving at St. Louis station via Chicago Bus Station station. The journey, including transfers, takes approximately 15h 15m.
Appleton to St. Louis bus services, operated by Flixbus USA, depart from Appleton Transit Center station.
Appleton to St. Louis bus services, operated by Flixbus USA, arrive at St Louis Bus Station.
Book your Appleton to St. Louis bus tickets online with Flixbus USA.
The distance between Appleton and St. Louis is 643.9 km. The road distance is 823 km.
You can take a bus from Appleton Transit Center to St Louis Bus Station via Chicago Bus Station in around 11h 25m.