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How to get fromAppleton to St. Louisby plane, bus, train, bus (Flixbus), or car

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There are 7 ways to get from Appleton to St. Louis by plane, bus, train, bus (Flixbus), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Appleton International Airport

    best
    1. Fly from Appleton International Airport (ATW) to Lambert–St. Louis International Airport (STL)plane plane ATW - STL
    4h 28m
    $111–575

  2. Bus (Flixbus)

    cheapest
    1. Take the bus from Appleton Transit Center to Chicago Bus Stationbus bus FlixBus 2550
    2. Take the bus from Chicago Bus Station to St Louis Bus Stationbus bus FlixBus 2510 / ...
    11h 25m
    $66–118

  3. Bus, train

    1. Take the bus from Appleton Transit Center to Chicago Bus Stationbus bus FlixBus 2550
    2. Take the train from Chicago Union Station to St. Louistrain train Lincoln Service / ...
    10h 25m
    $106–223

  4. Drive 443.4 mi

    1. Drive from Appleton to St. Louiscar car 443.4 mi
    7h 33m
    $81–117

  5. Fly from Green Bay

    1. Fly from Green Bay (GRB) to Lambert–St. Louis International Airport (STL)plane plane GRB - STL
    5h 55m
    $129–595

  6. Bus to General Mitchell International Airport, fly

    1. Take the bus from Appleton to Milwaukee Airportbus bus
    2. Fly from General Mitchell International Airport (MKE) to Lambert–St. Louis International Airport (STL)plane plane MKE - STL
    6h 8m
    $138–878

  7. Bus, train via Milwaukee

    1. Take the bus from Appleton to Milwaukeebus bus
    2. Take the train from Milwaukee to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to St. Louistrain train
    10h 50m
    $118–258

Appleton to St. Louis by bus, foot, and train

Calendar5Weekly Services
Duration10h 25mAverage Duration
Ticket$106Cheapest Price
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Questions & Answers

What companies run services between Appleton, WI, USA and St. Louis, MO, USA?

United Airlines, American Airlines, and Delta fly from Appleton International Airport (ATW) to Lambert–St. Louis International Airport (STL) hourly. Alternatively, you can take a bus from Appleton Transit Center to St Louis Bus Station via Chicago Bus Station in around 11h 25m.

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