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How to get fromSanta Ana to Key Westby plane, train, bus, ferry or car

Find Transport to Key West

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There are 5 ways to get from Santa Ana to Key West by plane, train, bus, ferry, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from John Wayne Airport Orange County

    best
    1. Fly from John Wayne Airport Orange County (SNA) to Key West International Airport (EYW)planeSNA - EYW
    7h 43m
    $248–945

  2. Train, bus, ferry

    1. Take the train from Santa Ana to Los Angelestrain
    2. Take the train from Los Angeles to Houstontrain
    3. Take the bus from Houston - Harrisburg Blvd to Fort Myersbus
    4. Take the ferry from Fort Myers Beach, FL to Key West, FLferry
    2d 16h
    $571–1,821

  3. Drive 2,815.9 mi

    1. Drive from Santa Ana to Key Westcar2,815.9 mi
    46h 46m
    $514–743

  4. Train to Los Angeles International Airport, fly

    1. Take the train from Santa Ana to L.A. Union Stationtrain
    2. Fly from Los Angeles International Airport (LAX) to Key West International Airport (EYW)planeLAX - EYW
    9h 30m
    $280–987

  5. Train to San Diego International Airport, fly

    1. Take the train from Santa Ana to San Diego Old Town Transportation Centertrain
    2. Fly from San Diego International Airport (SAN) to Key West International Airport (EYW)planeSAN - EYW
    10h 30m
    $288–1,144

John Wayne Airport Orange County (SNA) to Key West International Airport (EYW) flights

Calendar13Weekly Planes
Duration10hAverage Duration
Ticket$216Cheapest Price
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Questions & Answers

What companies run services between Santa Ana, CA, USA and Key West, FL, USA?

Delta and American Airlines fly from John Wayne Airport Orange County (SNA) to Key West International Airport (EYW) twice daily.

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