There are 7 ways to get from Charlotte to Key West by plane, bus (Flixbus, Greyhound), train, bus, car, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Charlotte Douglas International Airport
best- Fly from Charlotte Douglas International Airport (CLT) to Key West International Airport (EYW)plane CLT - EYW
3h 49m$123–475Fly from Concord
cheapest- Fly from Concord (USA) to Key West International Airport (EYW)plane USA - EYW
6h 55m$103–375Bus
- Take the bus from Charlotte Bus Station to Orlando Bus Stationbus
- Take the bus from Orlando Bus Station to Miami Airport Stationbus
- Take the bus from Miami Airport Station to Big Pine Keybus
- Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus Lks
22h 44m$114–279Train, bus
- Take the train from Charlotte Amtrak Station to Carytrain
- Take the train from Cary to Miami Amtrak Stationtrain
- Take the bus from Miami Airport Station to Big Pine Keybus
- Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus Lks
32h 59m$155–414Drive 882.8 mi
- Drive from Charlotte to Key Westcar 882.8 mi
15h 24m$162–233Bus to Greenville–Spartanburg International Airport, fly
- Take the bus from Charlotte, NC to Greenville, SCbus
- Fly from Greenville–Spartanburg International Airport (GSP) to Key West International Airport (EYW)plane GSP - EYW
6h 40m$206–766Bus via Macon
- Take the bus from Charlotte Bus Station to Macon Bus Stationbus
- Take the bus from Macon Bus Station to Miami Airport Stationbus
- Take the bus from Miami Airport Station to Big Pine Keybus
- Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus Lks
31h 1m$187–296
Charlotte to Key West by bus and foot
Questions & Answers
The cheapest way to get from Charlotte to Key West is to bus which costs $110 - $280 and takes 22h 44m.
The fastest way to get from Charlotte to Key West is to fly which takes 3h 49m and costs $120 - $480.
No, there is no direct bus from Charlotte station to Key West. However, there are services departing from Charlotte Bus Station and arriving at N Roosevelt & 3rd Street via Orlando Bus Station, Miami Airport Station and Big Pine Key - CVS / MM30. The journey, including transfers, takes approximately 22h 44m.
The distance between Charlotte and Key West is 753 miles. The road distance is 888 miles.
The best way to get from Charlotte to Key West without a car is to bus which takes 22h 44m and costs $110 - $280.
It takes approximately 3h 49m to get from Charlotte to Key West, including transfers.
Charlotte to Key West bus services, operated by Flixbus USA, depart from Charlotte Bus Station.
The best way to get from Charlotte to Key West is to fly which takes 3h 49m and costs $120 - $480. Alternatively, you can bus, which costs $110 - $280 and takes 22h 44m.
Charlotte to Key West bus services, operated by Flixbus USA, arrive at Orlando Bus Station.
Yes, the driving distance between Charlotte to Key West is 888 miles. It takes approximately 15h 24m to drive from Charlotte to Key West.
What companies run services between Charlotte, NC, USA and Key West, FL, USA?
American Airlines and Delta fly from Charlotte Douglas International Airport (CLT) to Key West International Airport (EYW) every 3 hours. Alternatively, you can take a bus from Charlotte Bus Station to N Roosevelt & 3rd Street via Orlando Bus Station, Miami Airport Station, Big Pine Key, and Big Pine Key - CVS / MM30 in around 22h 44m.
- Website
- aa.com
Flights from Charlotte Douglas International Airport to Key West International Airport
- Ave. Duration
- 2h 21m
- When
- Every day
- Estimated price
- $85–470
Flights from Charlotte Douglas International Airport to Key West International Airport via Miami
- Ave. Duration
- 4h 36m
- When
- Every day
- Estimated price
- $90–470
Flights from Greenville–Spartanburg International Airport to Key West International Airport via Miami
- Ave. Duration
- 4h 23m
- When
- Every day
- Estimated price
- $120–650
Flights from Greenville–Spartanburg International Airport to Key West International Airport via Charlotte Douglas International Airport
- Ave. Duration
- 5h 13m
- When
- Every day
- Estimated price
- $120–650
- Website
- delta.com
Flights from Charlotte Douglas International Airport to Key West International Airport via Atlanta
- Ave. Duration
- 4h 52m
- When
- Every day
- Estimated price
- $95–500
Flights from Greenville–Spartanburg International Airport to Key West International Airport via Atlanta
- Ave. Duration
- 4h 58m
- When
- Every day
- Estimated price
- $120–650
- Website
- allegiantair.com
Flights from Concord to Key West International Airport via St. Petersburg
- Ave. Duration
- 5h 22m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $60–320
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Charlotte Amtrak Station to Cary
- Ave. Duration
- 3h 1m
- Frequency
- 5 times a day
- Estimated price
- $30–45
- Website
- https://www.amtrak.com/home.html
Train from Cary to Miami Amtrak Station
- Ave. Duration
- 21h 58m
- Frequency
- Once daily
- Estimated price
- $75–300
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Charlotte Bus Station to Orlando Bus Station
- Ave. Duration
- 10h 15m
- Frequency
- Twice daily
- Estimated price
- $60–170
- Schedules at
- flixbus.com
Bus from Orlando Bus Station to Miami Airport Station
- Ave. Duration
- 4h 50m
- Frequency
- Every 2 hours
- Estimated price
- $27–65
- Schedules at
- flixbus.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Orlando Bus Station to Miami Airport Station
- Ave. Duration
- 6h 30m
- Frequency
- 3 times a day
- Estimated price
- $28–55
- Website
- https://www.greyhound.com/
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 35m
- Frequency
- 3 times a day
- Estimated price
- $22–40
- Website
- https://www.greyhound.com/
Bus from Macon Bus Station to Miami Airport Station
- Ave. Duration
- 15h 45m
- Frequency
- Once daily
- Estimated price
- $60–140
- Website
- https://www.greyhound.com/
- Phone
- +1 305-809-3700
- Website
- cityofkeywest-fl.gov
Bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Street
- Ave. Duration
- 1h 9m
- Frequency
- Every 3 hours
- Estimated price
- $2–4
- Schedules at
- https://www.cityofkeywest-fl.gov/595/Schedules-and-Route-Maps
- Phone
- +1 646-630-7186
- help@wandacoach.com
- Website
- wandacoach.com
Bus from Charlotte, NC to Greenville, SC
- Ave. Duration
- 1h 20m
- Frequency
- 3 times a day
- Estimated price
- $35–55
- Website
- https://www.wandacoach.com
- Book at
- https://www.gotobus.com/wanda-travel/
- Phone
- +1 404-591-2750
- info@southeasternstages.com
- Website
- southeasternstages.com
Bus from Charlotte Bus Station to Macon Bus Station
- Ave. Duration
- 7h 25m
- Frequency
- Once daily
- Estimated price
- $100–115
- Schedules at
- southeasternstages.com
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