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How to get fromIowa to Key Westby plane, bus (Flixbus, Greyhound), bus, train or car

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There are 8 ways to get from Iowa to Key West by plane, bus (Flixbus, Greyhound), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Des Moines

    best
    1. Fly from Des Moines (DSM) to Key West International Airport (EYW)planeDSM - EYW
    5h 16m
    $239–1,034
  2. Fly from Quad City International Airport

    cheapest
    1. Fly from Quad City International Airport (MLI) to Key West International Airport (EYW)planeMLI - EYW
    6h 59m
    $133–615
  3. Bus

    1. Take the bus from Des Moines to Champaignbus
    2. Take the bus from Champaign Intermodal Trans Ctr to Atlanta Bus Stationbus
    3. Take the bus from Atlanta Bus Station to Miami Airport Stationbus
    4. Take the bus from Miami Airport Station to Big Pine Keybus
    5. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd StreetbusLks
    44h 26m
    $254–562
  4. Bus, train

    1. Take the bus from Des Moines to Chicagobus
    2. Take the train from Chicago Union Station to Miami Amtrak Stationtrain
    3. Take the bus from Miami Airport Station to Big Pine Keybus
    4. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd StreetbusLks
    2d 13h
    $353–977
  5. Drive 1,679.3 mi

    1. Drive from Des Moines to Key Westcar1,679.3 mi
    30h 2m
    $307–443
  6. Fly from The Eastern Iowa Airport

    1. Fly from The Eastern Iowa Airport (CID) to Key West International Airport (EYW)planeCID - EYW
    7h
    $153–653
  7. Fly from Waterloo Municipal Airport

    1. Fly from Waterloo Municipal Airport (ALO) to Key West International Airport (EYW)planeALO - EYW
    6h 19m
    $160–685
  8. Fly from Omaha

    1. Fly from Omaha (OMA) to Key West International Airport (EYW)planeOMA - EYW
    8h 24m
    $244–1,116

Iowa to Key West by bus and foot

Calendar7Weekly Services
Duration44h 26mAverage Duration
Ticket$254Cheapest Price
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Questions & Answers

What companies run services between Iowa, USA and Key West, FL, USA?

Delta, United Airlines, and two other airlines fly from Des Moines (DSM) to Key West International Airport (EYW) every 4 hours. Alternatively, you can take a bus from Des Moines to N Roosevelt & 3rd Street via Champaign, Champaign Intermodal Trans Ctr, Atlanta Bus Station, Miami Airport Station, Big Pine Key, and Big Pine Key - CVS / MM30 in around 44h 26m.

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