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How to get fromIowa to Key Westby plane, bus, train, shuttle or car

Find Transport to Key West

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There are 9 ways to get from Iowa to Key West by plane, bus, train, shuttle, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Des Moines

    best
    1. Fly from Des Moines (DSM) to Key West International Airport (EYW)plane plane DSM - EYW
    5h 50m
    $259–1,134

  2. Fly from Quad City International Airport

    cheapest
    1. Fly from Quad City International Airport (MLI) to Key West International Airport (EYW)plane plane MLI - EYW
    9h 4m
    $143–665

  3. Bus, train, shuttle

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus
    2. Take the train from Chicago Union Station to Miami Amtrak Stationtrain train
    3. Take a shuttle bus from Miami, FL - International Airport to Key West, FLshuttle bus
    2d 13h
    $398–947

  4. Bus, train via Newark

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus
    2. Take the bus from Chicago Bus Station to Newark Penn Stationbus bus
    3. Take the train from Newark Penn Station to Miami Amtrak Stationtrain train
    4. Take the bus from Miami Airport Station to Big Pine Keybus bus
    5. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus bus Lks
    2d 15h
    $357–1,073

  5. Drive 1,679.3 mi

    1. Drive from Des Moines to Key Westcar car 1,679.3 mi
    30h 19m
    $307–443

  6. Fly from Waterloo Municipal Airport

    1. Fly from Waterloo Municipal Airport (ALO) to Key West International Airport (EYW)plane plane ALO - EYW
    8h 31m
    $170–735

  7. Bus to The Eastern Iowa Airport, fly

    1. Take the bus from Court St Transportation Center to GTC Bay 9bus bus
    2. Fly from The Eastern Iowa Airport (CID) to Key West International Airport (EYW)plane plane CID - EYW
    9h 38m

  8. Fly from Omaha

    1. Fly from Omaha (OMA) to Key West International Airport (EYW)plane plane OMA - EYW
    8h 18m
    $254–1,216

  9. Bus, train

    1. Take the bus from Des Moines to St. Paulbus bus
    2. Take the train from St. Paul-Minneapolis to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Miami Amtrak Stationtrain train
    4. Take the bus from Miami Airport Station to Big Pine Keybus bus
    5. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus bus Lks
    2d 19h
    $310–1,003

Des Moines (DSM) to Key West International Airport (EYW) flights

Calendar27Weekly Planes
Duration6h 33mAverage Duration
Ticket$237Cheapest Price
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Questions & Answers

What companies run services between Iowa, USA and Key West, FL, USA?

American Airlines and Delta fly from Des Moines (DSM) to Key West International Airport (EYW) 4 times a day.

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