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How to get fromIowa to Key Westby plane, bus, train, shuttle or car

Find Transport to Key West

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There are 7 ways to get from Iowa to Key West by plane, bus, train, shuttle, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Des Moines

    best
    1. Fly from Des Moines (DSM) to Key West International Airport (EYW)plane plane DSM - EYW
    6h 32m
    $279–1,234

  2. Fly from Quad City International Airport

    cheapest
    1. Fly from Quad City International Airport (MLI) to Key West International Airport (EYW)plane plane MLI - EYW
    6h 46m
    $143–665

  3. Bus, train, shuttle

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus
    2. Take the train from Chicago Union Station to Miami Amtrak Stationtrain train
    3. Take a shuttle bus from Miami, FL - International Airport to Key West, FLshuttle bus
    2d 13h
    $448–772

  4. Bus, train

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus
    2. Take the bus from Chicago Bus Station to Newark Penn Stationbus bus
    3. Take the train from Newark Penn Station to Miami Amtrak Stationtrain train
    4. Take the bus from Miami Airport Station to Big Pine Keybus bus
    5. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus bus Lks
    2d 15h
    $346–727

  5. Drive 1,679.3 mi

    1. Drive from Des Moines to Key Westcar car 1,679.3 mi
    30h 19m
    $307–443

  6. Fly from Waterloo Municipal Airport

    1. Fly from Waterloo Municipal Airport (ALO) to Key West International Airport (EYW)plane plane ALO - EYW
    6h 8m
    $170–735

  7. Fly from Omaha

    1. Fly from Omaha (OMA) to Key West International Airport (EYW)plane plane OMA - EYW
    7h 53m
    $244–1,116

Des Moines (DSM) to Key West International Airport (EYW) flights

Calendar34Weekly Planes
Duration7h 10mAverage Duration
Ticket$258Cheapest Price
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Questions & Answers

What companies run services between Iowa, USA and Key West, FL, USA?

American Airlines and Delta fly from Des Moines (DSM) to Key West International Airport (EYW) 5 times a day.

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