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How to get fromIowa to Key Westby plane, bus, train, shuttle, or car

Find Transport to Key West

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There are 7 ways to get from Iowa to Key West by plane, bus, train, shuttle, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Des Moines

    best
    1. Fly from Des Moines (DSM) to Key West International Airport (EYW)plane plane DSM - EYW
    5h 15m
    $169–684

  2. Fly from Quad City International Airport

    cheapest
    1. Fly from Quad City International Airport (MLI) to Key West International Airport (EYW)plane plane MLI - EYW
    7h 35m
    $103–415

  3. Bus, train, shuttle

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus
    2. Take the train from Chicago Union Station to Miami Amtrak Stationtrain train
    3. Take a shuttle bus from Miami, FL - International Airport to Key West, FLshuttle bus
    2d 13h
    $850–1,643

  4. Bus, train via Newark

    1. Take the bus from Des Moines to Indianapolis Union Stationbus bus
    2. Take the bus from Indianapolis to Newark Penn Stationbus bus
    3. Take the train from Newark Penn Station to Miami Amtrak Stationtrain train
    4. Take the bus from Miami Airport Station to Big Pine Keybus bus
    5. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus bus Lks
    2d 14h
    $608–1,228

  5. Drive 1,668.2 mi

    1. Drive from Des Moines to Key Westcar car 1,668.2 mi
    30h 46m
    $305–440

  6. Fly from Waterloo Municipal Airport

    1. Fly from Waterloo Municipal Airport (ALO) to Key West International Airport (EYW)plane plane ALO - EYW
    9h 9m
    $130–465

  7. Bus, train

    1. Take the bus from Des Moines to Galesburgbus bus
    2. Take the train from Galesburg Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Miami Amtrak Stationtrain train
    4. Take the bus from Miami Airport Station to Big Pine Keybus bus
    5. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus bus Lks
    2d 15h
    $723–1,538

Des Moines (DSM) to Key West International Airport (EYW) flights

Calendar45Weekly Planes
Duration6h 43mAverage Duration
Ticket$144Cheapest Price
See schedules

Questions & Answers

Map of how to get from Iowa to Key West.ExpandLaunch map view
  • Distance: 1,366.1 mi
  • Duration: 5h 15m

What companies run services between Iowa, USA and Key West, FL, USA?

Delta, Allegiant Air, and two other airlines fly from Des Moines (DSM) to Key West International Airport (EYW) every 4 hours.

Airlines
Train operators
Bus operators

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