There are 8 ways to get from Rochester to Santa Ana by plane, train (Amtrak), bus (Flixbus, Greyhound, Amtrak), car, train, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Rochester to John Wayne Airport Orange County
best- Fly from Rochester (ROC) to John Wayne Airport Orange County (SNA)plane ROC - SNA
8h 7m$326–1,355Fly Rochester to Los Angeles International Airport, train
cheapest- Fly from Rochester (ROC) to Los Angeles International Airport (LAX)plane ROC - LAX
- Take the train from Los Angeles to Santa Anatrain
10h 26m$203–805Train (Amtrak)
- Take the train from Rochester to Chicago Union Stationtrain Lake Shore Limited
- Take the train from Chicago Union Station to Fullerton Amtrak Stationtrain Southwest Chief
2d 8h$769–1,761Bus
- Take the bus from Rochester Bus Stop to Buffalobus
- Take the bus from Buffalo, NY to Columbus - Mound Stbus
- Take the bus from Columbus to St Louis Bus Stationbus
- Take the bus from St Louis Bus Station to Los Angeles Union Stationbus
- Take the bus from Los Angeles to Santa Anabus
2d 13h$456–912Drive 2,595.1 mi
- Drive from Rochester to Santa Anacar 2,595.1 mi
41h 25m$474–685Fly Rochester to Long Beach Airport
- Fly from Rochester (ROC) to Long Beach Airport (LGB)plane ROC - LGB
10h 48m$241–1,027Fly Rochester to Ontario International Airport, train
- Fly from Rochester (ROC) to Ontario International Airport (ONT)plane ROC - ONT
- Take the train from San Bernardino Depot to Santa Anatrain
12h 3m$358–1,537Bus to Buffalo Niagara International Airport, fly to Los Angeles International Airport, train
- Take the bus from Rochester Bus Stop to Buffalo Niagara International Airportbus
- Fly from Buffalo Niagara International Airport (BUF) to Los Angeles International Airport (LAX)plane BUF - LAX
- Take the train from Los Angeles to Santa Anatrain
10h 22m$225–949
Rochester to Santa Ana by train and bus (Amtrak)
Questions & Answers
The cheapest way to get from Rochester to Santa Ana is to fly and train which costs $200 - $850 and takes 10h 26m.
The fastest way to get from Rochester to Santa Ana is to fly which takes 8h 7m and costs $320 - $1,400.
No, there is no direct bus from Rochester to Santa Ana. However, there are services departing from Rochester Bus Stop and arriving at Santa Ana via Buffalo, NY, Columbus, St Louis Bus Station and Los Angeles. The journey, including transfers, takes approximately 2 days 13h.
The distance between Rochester and Santa Ana is 2272 miles. The road distance is 2610.2 miles.
The best way to get from Rochester to Santa Ana without a car is to train which takes 2 days 8h and costs $750 - $1,800.
It takes approximately 8h 7m to get from Rochester to Santa Ana, including transfers.
Rochester to Santa Ana bus services, operated by Flixbus USA, depart from Rochester Bus Stop station.
The best way to get from Rochester to Santa Ana is to fly which takes 8h 7m and costs $320 - $1,400. Alternatively, you can train, which costs $750 - $1,800 and takes 2 days 8h, you could also bus, which costs $450 - $950 and takes 2 days 13h.
Rochester to Santa Ana bus services, operated by Flixbus USA, arrive at Buffalo station.
Santa Ana is 3h behind Rochester. It is currently 5:58 AM in Rochester and 2:58 AM in Santa Ana.
What companies run services between Rochester, NY, USA and Santa Ana, CA, USA?
United Airlines, Delta, and American Airlines fly from Rochester (ROC) to John Wayne Airport Orange County (SNA) every 3 hours. Alternatively, you can take a train from Rochester to Main-Civic Center via Chicago Union Station, Fullerton Amtrak Station, Fullerton Trans Ctr Dock 1, and Harbor-East Shuttle Area in around 2d 8h.
- Website
- delta.com
Flights from Rochester to John Wayne Airport Orange County via Atlanta
- Ave. Duration
- 9h 21m
- When
- Every day
- Estimated price
- $330–1,400
Flights from Rochester to John Wayne Airport Orange County via New York JFK
- Ave. Duration
- 8h 49m
- When
- Every day
- Estimated price
- $340–1,500
Flights from Rochester to Los Angeles International Airport via Detroit
- Ave. Duration
- 8h 5m
- When
- Every day
- Estimated price
- $170–750
Flights from Rochester to Los Angeles International Airport via Atlanta
- Ave. Duration
- 9h 5m
- When
- Every day
- Estimated price
- $190–850
Flights from Rochester to Ontario International Airport via Atlanta
- Ave. Duration
- 8h 31m
- When
- Every day
- Estimated price
- $380–1,600
Flights from Buffalo Niagara International Airport to Los Angeles International Airport via Minneapolis
- Ave. Duration
- 7h 8m
- When
- Every day
- Estimated price
- $210–900
Flights from Buffalo Niagara International Airport to Los Angeles International Airport via Detroit
- Ave. Duration
- 7h 58m
- When
- Every day
- Estimated price
- $200–900
- Website
- united.com
Flights from Rochester to John Wayne Airport Orange County via Chicago O'Hare
- Ave. Duration
- 8h 9m
- When
- Every day
- Estimated price
- $280–1,300
Flights from Rochester to John Wayne Airport Orange County via Newark
- Ave. Duration
- 12h 7m
- When
- Every day
- Estimated price
- $330–1,400
Flights from Rochester to Los Angeles International Airport via Chicago O'Hare
- Ave. Duration
- 8h 4m
- When
- Every day
- Estimated price
- $170–750
Flights from Rochester to Los Angeles International Airport via Washington Dulles
- Ave. Duration
- 9h 4m
- When
- Every day
- Estimated price
- $190–800
Flights from Rochester to Ontario International Airport via Chicago O'Hare
- Ave. Duration
- 8h 7m
- When
- Every day
- Estimated price
- $330–1,500
Flights from Buffalo Niagara International Airport to Los Angeles International Airport via Denver
- Ave. Duration
- 7h 31m
- When
- Every day
- Estimated price
- $200–900
- Website
- southwest.com
Flights from Rochester to Los Angeles International Airport via Chicago Midway
- Ave. Duration
- 7h 37m
- When
- Every day
- Estimated price
- $170–750
Flights from Rochester to Los Angeles International Airport via Baltimore
- Ave. Duration
- 8h 17m
- When
- Tuesday, Wednesday, and Sunday
- Estimated price
- $190–850
Flights from Rochester to Long Beach Airport via Chicago Midway
- Ave. Duration
- 7h 35m
- When
- Monday, Thursday, and Friday
- Estimated price
- $220–1,000
Flights from Rochester to Long Beach Airport via Chicago Midway, Denver
- Ave. Duration
- 9h 35m
- When
- Monday to Friday
- Estimated price
- $220–1,000
Flights from Rochester to Long Beach Airport via Chicago Midway, Phoenix
- Ave. Duration
- 12h 45m
- When
- Saturday
- Estimated price
- $230–1,000
Flights from Rochester to Ontario International Airport via Chicago Midway
- Ave. Duration
- 8h 25m
- When
- Every day
- Estimated price
- $330–1,500
Flights from Rochester to Ontario International Airport via Baltimore
- Ave. Duration
- 12h 10m
- When
- Every day
- Estimated price
- $370–1,600
Flights from Buffalo Niagara International Airport to Los Angeles International Airport via Chicago Midway
- Ave. Duration
- 7h 21m
- When
- Tuesday, Wednesday, and Sunday
- Estimated price
- $200–900
Flights from Buffalo Niagara International Airport to Los Angeles International Airport via Dallas
- Ave. Duration
- 7h 25m
- When
- Saturday
- Estimated price
- $220–950
Flights from Buffalo Niagara International Airport to Los Angeles International Airport via Phoenix
- Ave. Duration
- 7h 30m
- When
- Sunday
- Estimated price
- $210–900
Flights from Buffalo Niagara International Airport to Los Angeles International Airport via Las Vegas
- Ave. Duration
- 7h 45m
- When
- Monday, Thursday, and Friday
- Estimated price
- $200–900
Flights from Buffalo Niagara International Airport to Los Angeles International Airport via Denver
- Ave. Duration
- 8h 20m
- When
- Saturday
- Estimated price
- $200–900
- Website
- aa.com
Flights from Rochester to John Wayne Airport Orange County via Chicago O'Hare
- Ave. Duration
- 10h 51m
- When
- Every day
- Estimated price
- $280–1,300
Flights from Rochester to John Wayne Airport Orange County via Charlotte
- Ave. Duration
- 10h 44m
- When
- Every day
- Estimated price
- $330–1,400
Flights from Rochester to Los Angeles International Airport via Chicago O'Hare
- Ave. Duration
- 8h 58m
- When
- Every day
- Estimated price
- $170–750
Flights from Rochester to Los Angeles International Airport via Reagan Washington
- Ave. Duration
- 9h 37m
- When
- Every day
- Estimated price
- $190–850
Flights from Rochester to Ontario International Airport via Charlotte
- Ave. Duration
- 9h 57m
- When
- Every day
- Estimated price
- $380–1,600
- Website
- jetblue.com
Flights from Buffalo Niagara International Airport to Los Angeles International Airport
- Ave. Duration
- 5h 24m
- When
- Every day
- Estimated price
- $200–900
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Rochester to Chicago Union Station
- Ave. Duration
- 11h 43m
- Frequency
- Twice daily
- Estimated price
- $160–360
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to Fullerton Amtrak Station
- Ave. Duration
- 42h 44m
- Frequency
- Twice daily
- Estimated price
- $600–1,400
- Website
- https://www.amtrak.com/home.html
Train from Los Angeles to Santa Ana
- Ave. Duration
- 50 min
- Frequency
- Every 2 hours
- Estimated price
- $9–22
- Website
- https://www.amtrak.com/home.html
- Phone
- (800) 371-LINK (5465)
- Website
- metrolinktrains.com
Train from San Bernardino Depot to Santa Ana
- Ave. Duration
- 1h 16m
- Frequency
- 3 times a day
- Estimated price
- $3–5
- Website
- https://metrolinktrains.com
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Rochester Bus Stop to Buffalo
- Ave. Duration
- 1h 20m
- Frequency
- Every 3 hours
- Estimated price
- $9–17
- Schedules at
- flixbus.com
Bus from Rochester Bus Stop to Buffalo Niagara International Airport
- Ave. Duration
- 1h 10m
- Frequency
- Every 4 hours
- Estimated price
- $8–15
- Schedules at
- flixbus.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Rochester Bus Stop to Buffalo
- Ave. Duration
- 1h 25m
- Frequency
- 4 times a day
- Estimated price
- $12–24
- Website
- https://www.greyhound.com/
Bus from Columbus to St Louis Bus Station
- Ave. Duration
- 9h 5m
- Frequency
- 3 times a day
- Estimated price
- $70–140
- Website
- https://www.greyhound.com/
Bus from St Louis Bus Station to Los Angeles Union Station
- Ave. Duration
- 38h 45m
- Frequency
- Twice daily
- Estimated price
- $330–650
- Website
- https://www.greyhound.com/
- Phone
- +1 888-378-3823
- info@baronsbus.com
- Website
- baronsbus.com
Bus from Buffalo, NY to Columbus - Mound St
- Ave. Duration
- 7h 5m
- Frequency
- Once daily
- Estimated price
- $35–80
- Website
- https://baronsbus.com
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Los Angeles to Santa Ana
- Ave. Duration
- 1h 5m
- Frequency
- Once daily
- Estimated price
- $11–18
- Website
- https://www.amtrak.com/home.html
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Need to know: Greyhound
Read the travel guide
More Questions & Answers
Yes, the driving distance between Rochester to Santa Ana is 2610 miles. It takes approximately 41h 25m to drive from Rochester to Santa Ana.
Book your Rochester to Santa Ana bus tickets online with Omio.
There are 2932+ hotels available in Santa Ana.












