There are 9 ways to get from Manzanillo to Santa Ana by plane, train, bus, car, or bus (Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Playa De Oro International Airport to Los Angeles International Airport, train
best- Fly from Playa De Oro International Airport (ZLO) to Los Angeles International Airport (LAX)plane ZLO - LAX
- Take the train from Los Angeles to Santa Anatrain
6h 47m$435–1,289Bus
cheapest- Take the bus from Manzanillo to Tren Ligerobus
- Take the bus from Terminal Sur De Autobuses to Parque Metropolitanobus
- Take the bus from Guadalajara to Santa Anabus
39h 3m$111–266Bus, train via Santa Ana
- Take the bus from Manzanillo to Santa Anabus
- Take the bus from Santa Ana to Mexicalibus
- Take the bus from Mexicali to Tijuanabus
- Take the train from San Diego to Santa Anatrain
31h 49m$256–460Drive 1,606.2 mi
- Drive from Manzanillo to Santa Anacar 1,606.2 mi
30h 56m$294–424Bus to Licenciado Miguel De La Madrid Airport, fly to Tijuana International Airport, bus
- Take the bus from Manzanillo to Colimabus
- Fly from Licenciado Miguel De La Madrid Airport (CLQ) to Tijuana International Airport (TIJ)plane CLQ - TIJ
- Take the bus from Tijuana Aeropuerto, B.C. to Santa Anabus
10h 27m$196–415Bus to Licenciado Gustavo Díaz Ordaz International Airport, fly to John Wayne Airport Orange County
- Take the bus from Manzanillo to Puerto Vallartabus
- Fly from Licenciado Gustavo Díaz Ordaz International Airport (PVR) to John Wayne Airport Orange County (SNA)plane PVR - SNA
10h 12m$160–616Bus, drive, train
- Take the bus from Manzanillo to Santa Anabus
- Drive from Santa Ana to 219 N Arroyo Blvd - Nogalescar
- Take the bus from 219 N Arroyo Blvd - Nogales to 4207 S 6th Ave - Tucsonbus
- Take the train from Tucson Amtrak Station to Los Angelestrain
- Take the train from Los Angeles to Santa Anatrain
33h 12m$491–763Bus, train
- Take the bus from Manzanillo to Tijuanabus
- Take the train from San Diego to Santa Anatrain Pacific Surfliner
47h 1m$272–425Bus via Los Angeles
- Take the bus from Manzanillo to Nueva Central Camionera de Guadalajara Mod 1bus
- Take the bus from Terminal Tlaquepaque to Huntington Parkbus
- Take the bus from Huntington Park to Santa Anabus
2d$222–336
Manzanillo to Santa Ana by bus and foot
Comparing Your Travel Options
The cheapest way to get from Manzanillo to Santa Ana is to bus which costs $110 - $270 and takes 39h 3m.
The fastest way to get from Manzanillo to Santa Ana is to fly and train which takes 6h 47m and costs $430 - $1,300.
No, there is no direct bus from Manzanillo to Santa Ana. However, there are services departing from Parada en Av. Manzanillo 91 and arriving at Santa Ana via Manzanillo, Terminal Sur De Autobuses and Guadalajara. The journey, including transfers, takes approximately 39h 3m.
The distance between Manzanillo and Santa Ana is 1408 miles. The road distance is 1615.6 miles.
The best way to get from Manzanillo to Santa Ana without a car is to bus and train via Santa Ana which takes 31h 49m and costs $250 - $460.
It takes approximately 6h 47m to get from Manzanillo to Santa Ana, including transfers.
Manzanillo to Santa Ana bus services, operated by Autovías La Línea, depart from Manzanillo station.
Manzanillo to Santa Ana bus services, operated by Autovías La Línea, arrive at Tren Ligero station.
Santa Ana is 1h behind Manzanillo. It is currently 12:47 PM in Manzanillo and 11:47 AM in Santa Ana.
Yes, the driving distance between Manzanillo to Santa Ana is 1616 miles. It takes approximately 30h 56m to drive from Manzanillo to Santa Ana.
What companies run services between Manzanillo, Mexico and Santa Ana, CA, USA?
You can take a bus from Parada en Av. Manzanillo 91 to Santa Ana via Parada en Obras Maritimas 42, Manzanillo, Tren Ligero, Terminal Sur De Autobuses, Parque Metropolitano, and Guadalajara in around 39h 3m.
- Website
- aa.com
Flights from Playa De Oro International Airport to Los Angeles International Airport
- Ave. Duration
- 3h 35m
- When
- Thursday, Saturday, and Sunday
- Estimated price
- $370–1,200
Flights from Playa De Oro International Airport to Los Angeles International Airport via Dallas/Ft.Worth
- Ave. Duration
- 7h 38m
- When
- Saturday
- Estimated price
- $200–850
Flights from Playa De Oro International Airport to Los Angeles International Airport via Phoenix
- Ave. Duration
- 7h 15m
- When
- Wednesday and Saturday
- Estimated price
- $140–650
- Website
- southwest.com
Flights from Licenciado Gustavo Díaz Ordaz International Airport to John Wayne Airport Orange County
- Ave. Duration
- 3h 10m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $110–550
Flights from Licenciado Gustavo Díaz Ordaz International Airport to John Wayne Airport Orange County via Phoenix
- Ave. Duration
- 6h 5m
- When
- Saturday
- Estimated price
- $120–600
Flights from Licenciado Gustavo Díaz Ordaz International Airport to John Wayne Airport Orange County via Las Vegas
- Ave. Duration
- 6h 35m
- When
- Sunday
- Estimated price
- $130–650
- Website
- aeromexico.com
Flights from Playa De Oro International Airport to Los Angeles International Airport via Mexico City
- Ave. Duration
- 7h 35m
- When
- Every day
- Estimated price
- $170–750
Flights from Licenciado Gustavo Díaz Ordaz International Airport to John Wayne Airport Orange County via Salt Lake City
- Ave. Duration
- 7h 20m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $170–750
- Website
- delta.com
Flights from Playa De Oro International Airport to Los Angeles International Airport via Mexico City
- Ave. Duration
- 7h 35m
- When
- Every day
- Estimated price
- $170–750
Flights from Licenciado Gustavo Díaz Ordaz International Airport to John Wayne Airport Orange County via Salt Lake City
- Ave. Duration
- 7h 20m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $170–750
- Website
- volaris.com
Flights from Licenciado Miguel De La Madrid Airport to Tijuana International Airport
- Ave. Duration
- 2h 54m
- When
- Every day
- Estimated price
- $150–340
- Website
- alaskaair.com
Flights from Playa De Oro International Airport to Los Angeles International Airport
- Ave. Duration
- 3h 35m
- When
- Thursday, Saturday, and Sunday
- Estimated price
- $370–1,200
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Los Angeles to Santa Ana
- Ave. Duration
- 50 min
- Frequency
- Hourly
- Estimated price
- $19–30
- Website
- Amtrak
Train from San Diego to Santa Ana
- Ave. Duration
- 2h 1m
- Frequency
- Hourly
- Estimated price
- $50–80
- Website
- Amtrak
Train from Tucson Amtrak Station to Los Angeles
- Ave. Duration
- 10h 20m
- Frequency
- 6 times a week
- Estimated price
- $270–430
- Website
- Amtrak
Train from Los Angeles to Santa Ana
- Ave. Duration
- 50 min
- Frequency
- Hourly
- Estimated price
- $19–30
- Website
- Amtrak
Train from San Diego to Santa Ana
- Ave. Duration
- 2h 1m
- Frequency
- Hourly
- Estimated price
- $50–80
- Website
- Amtrak
- Phone
- +52 55 4440 3187
- servicioalcliente@geb.mx
- Website
- autobuseselite.com.mx
Bus from Manzanillo to Santa Ana
- Ave. Duration
- 14h 49m
- Frequency
- Once daily
- Estimated price
- $150–230
- Schedules at
- autobuseselite.com.mx
- Book at
- autobuseselite.com.mx
Bus from Santa Ana to Mexicali
- Ave. Duration
- 7h 52m
- Frequency
- 3 times a day
- Estimated price
- $50–80
- Schedules at
- autobuseselite.com.mx
- Book at
- autobuseselite.com.mx
Bus from Manzanillo to Santa Ana
- Ave. Duration
- 14h 49m
- Frequency
- Once daily
- Estimated price
- $150–230
- Schedules at
- autobuseselite.com.mx
- Book at
- autobuseselite.com.mx
Bus from Manzanillo to Tijuana
- Ave. Duration
- 37h 42m
- Frequency
- Once daily
- Estimated price
- $200–310
- Schedules at
- autobuseselite.com.mx
- Book at
- autobuseselite.com.mx
- Phone
- +52 644 410 2444
- atencionaclientes@tufesa.com.mx
- Website
- tufesa.com.mx
Bus from Santa Ana to Mexicali
- Ave. Duration
- 7h 20m
- Frequency
- Every 4 hours
- Estimated price
- $35–67
- Schedules at
- tufesa.com.mx
- Book at
- tufesa.com.mx
- Plus
- $35–55
- Titanium
- $40–55
Bus from Terminal Tlaquepaque to Huntington Park
- Ave. Duration
- 38h
- Frequency
- 3 times a day
- Estimated price
- $180–267
- Schedules at
- tufesa.com.mx
- Book at
- tufesa.com.mx
- Plus
- $180–260
- Titanium
- $205–215
- Phone
- +52 55 4440 3187
- servicioalcliente@geb.mx
- Website
- chihuahuenses.com.mx
Bus from Santa Ana to Mexicali
- Ave. Duration
- 7h 50m
- Frequency
- 4 times a day
- Estimated price
- $55–100
- Schedules at
- chihuahuenses.com.mx
- Book at
- chihuahuenses.com.mx
- Phone
- +52 664 299 0487
- servicios@acnautobuses.com
- Website
- acnautobuses.com
Bus from Santa Ana to Mexicali
- Ave. Duration
- 9h
- Frequency
- Once daily
- Estimated price
- $45–65
- Schedules at
- acnautobuses.com
- Book at
- acnautobuses.com
Bus from Guadalajara to Santa Ana
- Ave. Duration
- 32h 35m
- Frequency
- Once daily
- Estimated price
- $80–200
- Schedules at
- acnautobuses.com
- Book at
- acnautobuses.com
- Phone
- +52 664 104 7400
- servicioalcliente@geb.mx
- Website
- abc.com.mx
Bus from Mexicali to Tijuana
- Ave. Duration
- 2h 5m
- Frequency
- Every 3 hours
- Estimated price
- $19–35
- Schedules at
- abc.com.mx
- Book at
- abc.com.mx
- Phone
- 800 622 22 22
- buzondeatencion@gho.mx
- Website
- Autovías
Bus from Manzanillo to Colima
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- $10–22
- Website
- Autovías
Bus from Manzanillo to Tren Ligero
- Ave. Duration
- 3h 40m
- Frequency
- Hourly
- Estimated price
- $30–65
- Website
- Autovías
- Phone
- +1 866 691 9732
- eplasales@eplalimo.com
- Website
- Limousine Express
Bus from Tijuana Aeropuerto, B.C. to Santa Ana
- Ave. Duration
- 2h 30m
- Frequency
- 5 times a day
- Estimated price
- $30–45
- Website
- Limousine Express
- One Way
- $30–45
Bus from Huntington Park to Santa Ana
- Ave. Duration
- 1h 20m
- Frequency
- 4 times a day
- Estimated price
- $25–40
- Website
- Limousine Express
- One Way
- $25–40
Bus from Manzanillo to Puerto Vallarta
- Ave. Duration
- 3h 30m
- Frequency
- Every 4 hours
- Estimated price
- $20–29
- Schedules at
- Autocamiones del Pacifico
- Phone
- +1 800-923-1799
- contactus@omexusa.net
- Website
- Omnibus Express
Bus from 219 N Arroyo Blvd - Nogales to 4207 S 6th Ave - Tucson
- Ave. Duration
- 1h
- Frequency
- 3 times a day
- Estimated price
- $40–55
- Schedules at
- Omnibus Express
- Phone
- +52 33 3942 5700
- Website
- Siteur
Bus from Terminal Sur De Autobuses to Parque Metropolitano
- Ave. Duration
- 21 min
- Frequency
- Every 10 minutes
- Estimated price
- $1
- Schedules at
- Siteur
- Phone
- +52 477 710 0060
- Website
- primeraplus.com.mx
Bus from Manzanillo to Nueva Central Camionera de Guadalajara Mod 1
- Ave. Duration
- 4h 30m
- Frequency
- Hourly
- Estimated price
- $35–55
- Schedules at
- primeraplus.com.mx
- Book at
- primeraplus.com.mx
Bus from Huntington Park to Santa Ana
- Ave. Duration
- 1h
- Frequency
- Twice daily
- Estimated price
- $19–28
- Schedules at
- CBX Cross Border Express
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Huntington Park to Santa Ana
- Ave. Duration
- 1h 15m
- Frequency
- Twice daily
- Estimated price
- $7–11
- Schedules at
- Flixbus USA
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