There are 5 ways to get from Perugia to Isernia by bus, train (Trenitalia), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus via Rome
best- Take the bus from Perugia to Roma, Autostazione Tiburtina538 / ...
- Take the bus from Roma, Autostazione Tiburtina to IserniaRome Tiburtina
5h 30m€16–61Bus
cheapest- Take the bus from Perugia - Piazza Partigiani to Cassino
- Take the bus from Casello - A1 Ingresso Caianello to Isernia6
7h 8m€7–10Train
- Take the train from Perugia to Roma Termini4735 / ...
- Take the train from Roma Termini to IserniaRe
6h 13m€23–47Drive 324.7 km
- Drive from Perugia to Isernia324.7 km
3h 24m€51–73Train via Foligno
- Take the train from Foligno to Roma Tiburtina4153 / ...
- Take the train from Roma Tiburtina to IserniaRe
6h 34m€24–52
Perugia to Isernia by bus
Questions & Answers
The cheapest way to get from Perugia to Isernia is to bus which costs €6 - €10 and takes 7h 8m.
The fastest way to get from Perugia to Isernia is to drive which takes 3h 24m and costs €50 - €75.
No, there is no direct bus from Perugia to Isernia. However, there are services departing from Perugia and arriving at Isernia via Roma, Autostazione Tiburtina. The journey, including transfers, takes approximately 5h 30m.
No, there is no direct train from Perugia to Isernia. However, there are services departing from Perugia and arriving at Isernia via Roma Termini. The journey, including transfers, takes approximately 6h 13m.
The distance between Perugia and Isernia is 343 km. The road distance is 324.7 km.
The best way to get from Perugia to Isernia without a car is to bus via Rome which takes 5h 30m and costs €15 - €65.
It takes approximately 5h 30m to get from Perugia to Isernia, including transfers.
Perugia to Isernia bus services, operated by FlixBus, depart from Perugia station.
Perugia to Isernia train services, operated by Trenitalia S.p.A., depart from Foligno station.
The best way to get from Perugia to Isernia is to bus via Rome which takes 5h 30m and costs €15 - €65. Alternatively, you can train, which costs €22 - €50 and takes 6h 13m.
What companies run services between Perugia, Italy and Isernia, Italy?
You can take a bus from Perugia to Isernia via Roma, Autostazione Tiburtina in around 5h 30m. Alternatively, you can take a train from Perugia to Isernia via Roma Termini in around 6h 13m.
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Perugia to Roma Termini
- Ave. Duration
- 3h 5m
- Frequency
- 5 times a day
- Estimated price
- €21–35
- Website
- https://www.trenitalia.com/en.html
Train from Roma Termini to Isernia
- Ave. Duration
- 2h 8m
- Frequency
- 5 times a day
- Estimated price
- €11–17
- Website
- https://www.trenitalia.com/en.html
Train from Foligno to Roma Tiburtina
- Ave. Duration
- 1h 43m
- Frequency
- Every 2 hours
- Estimated price
- €15–26
- Website
- https://www.trenitalia.com/en.html
Train from Roma Tiburtina to Isernia
- Ave. Duration
- 2h 14m
- Frequency
- 6 times a week
- Estimated price
- €11–17
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Perugia to Roma Termini
- Ave. Duration
- 2h 20m
- Frequency
- 6 times a week
- Estimated price
- €11–27
- Website
- https://www.trenitalia.com/en.html
Train from Foligno to Roma Tiburtina
- Ave. Duration
- 1h 48m
- Frequency
- 3 times a day
- Estimated price
- €9–21
- Website
- https://www.trenitalia.com/en.html
Rome2Rio's guide to FlixBus
Contact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Perugia to Roma, Autostazione Tiburtina
- Ave. Duration
- 2h 20m
- Frequency
- Every 4 hours
- Estimated price
- €8–26
- Website
- https://www.flixbus.co.uk
Bus from Roma, Autostazione Tiburtina to Isernia
- Ave. Duration
- 2h 10m
- Frequency
- Once daily
- Estimated price
- €12–35
- Website
- https://www.flixbus.co.uk
- Phone
- +39 075 5009641
- info@sulga.it
- Website
- sulga.it
Bus from Perugia to Roma, Autostazione Tiburtina
- Ave. Duration
- 2h 30m
- Frequency
- 4 times a day
- Estimated price
- €22–26
- Schedules at
- sulga.it
- 2nd Class
- €22–26
- Phone
- +39 080 3112335
- info@marinobus.it
- Website
- marinobus.it
Bus from Perugia to Roma, Autostazione Tiburtina
- Ave. Duration
- 2h 40m
- Frequency
- Once daily
- Estimated price
- €18–25
- Website
- https://marinobus.it/en/
Bus from Perugia to Roma, Autostazione Tiburtina
- Ave. Duration
- 3h 15m
- Frequency
- 3 times a week
- Estimated price
- €7–12
- Schedules at
- autolineefederico.it
- Phone
- 0971 54673
- info@autolineeliscio.it
- Website
- autolineeliscio.it
Bus from Perugia to Roma, Autostazione Tiburtina
- Ave. Duration
- 2h 40m
- Frequency
- Twice a week
- Estimated price
- €10–15
- Schedules at
- autolineeliscio.it
- Phone
- +39 0972 24590
- booking@autolineemoretti.it
- Website
- autolineemoretti.it
Bus from Perugia to Roma, Autostazione Tiburtina
- Ave. Duration
- 2h 45m
- Frequency
- 3 times a week
- Estimated price
- €12–14
- Schedules at
- autolineemoretti.it
- Phone
- +39 0874 64744
- info@atm-molise.it
- Website
- atm-molise.it
Bus from Roma, Autostazione Tiburtina to Isernia
- Ave. Duration
- 2h 10m
- Frequency
- 3 times a day
- Estimated price
- €8–13
- Schedules at
- atm-molise.it
- Phone
- +39 089 233 899
- salerno@autolineecurcio.it
- Website
- autolineecurcio.it
Bus from Perugia - Piazza Partigiani to Cassino
- Ave. Duration
- 3h 35m
- Frequency
- Once daily
- Estimated price
- €2
- Website
- https://www.autolineecurcio.it/
- Phone
- 0865.221788
- info@satiautobus.com
- Website
- satiautobus.com
Bus from Casello - A1 Ingresso Caianello to Isernia
- Ave. Duration
- 55 min
- Frequency
- 3 times a day
- Estimated price
- €2–3
- Schedules at
- satiautobus.com
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More Questions & Answers
Perugia to Isernia bus services, operated by FlixBus, arrive at Roma, Autostazione Tiburtina station.
Perugia to Isernia train services, operated by Trenitalia S.p.A., arrive at Roma Tiburtina station.
Yes, the driving distance between Perugia to Isernia is 325 km. It takes approximately 3h 24m to drive from Perugia to Isernia.
Book your Perugia to Isernia train tickets online with Omio.
Book your Perugia to Isernia bus tickets online with Omio and FlixBus.
There are 422+ hotels available in Isernia.