There are 3 ways to get from Naples to Isernia by train (Trenitalia), bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Naples to Isernia by train (Trenitalia)
Comparing Your Travel Options
The cheapest way to get from Naples to Isernia is to bus which costs €4 - €15 and takes 2h 9m.
The fastest way to get from Naples to Isernia is to drive which takes 1h 24m and costs €19 - €28.
Yes, there is a direct bus departing from Napoli P.zza Garibaldi and arriving at Isernia. Services depart three times a day, and operate every day. The journey takes approximately 2h 9m.
Yes, there is a direct train departing from Napoli Centrale and arriving at Isernia. Services depart four times a day, and operate every day. The journey takes approximately 2h 5m.
The distance between Naples and Isernia is 130 km. The road distance is 106.3 km.
The best way to get from Naples to Isernia without a car is to train which takes 2h 5m and costs €15 - €22.
The train from Napoli Centrale to Isernia takes 2h 5m including transfers and departs four times a day.
Naples to Isernia bus services, operated by FlixBus, depart from Napoli P.zza Garibaldi station.
Naples to Isernia train services, operated by Trenitalia, depart from Napoli Centrale station.
The best way to get from Naples to Isernia is to train which takes 2h 5m and costs €15 - €22. Alternatively, you can bus, which costs €4 - €15 and takes 2h 9m.
What companies run services between Naples, Italy and Isernia, Italy?
Trenitalia operates a train from Napoli Centrale to Isernia 4 times a day. Tickets cost €15–22 and the journey takes 2h 5m. Alternatively, FlixBus operates a bus from Napoli P.zza Garibaldi to Isernia 3 times a day. Tickets cost €9–15 and the journey takes 2h 9m. Società Autocooperative Trasporti Italiani S.p.A. also services this route 3 times a day.
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Napoli Centrale to Isernia
- Ave. Duration
- 2h 5m
- Frequency
- 4 times a day
- Estimated price
- €15–22
- Website
- Trenitalia
Rome2Rio's guide to FlixBus
Contact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- Flixbus
Bus from Napoli P.zza Garibaldi to Isernia
- Ave. Duration
- 2h 9m
- Frequency
- 3 times a day
- Estimated price
- €9–15
- Website
- Flixbus
- Phone
- 0865.221788
- info@satiautobus.com
- Website
- satiautobus.com
Bus from Napoli P.zza Garibaldi to Isernia
- Ave. Duration
- 1h 50m
- Frequency
- 3 times a day
- Estimated price
- €4–10
- Schedules at
- satiautobus.com
Want to know more about travelling around Italy
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Italy Travel Guides
Read the travel guide
Want to know more about Flixbus?
Read the travel guide
Booking & Getting There
Naples to Isernia bus services, operated by FlixBus, arrive at Isernia station.
Naples to Isernia train services, operated by Trenitalia, arrive at Isernia station.
Yes, the driving distance between Naples to Isernia is 106 km. It takes approximately 1h 24m to drive from Naples to Isernia.
Book your Naples to Isernia train tickets online with Omio.
Book your Naples to Isernia bus tickets online with Omio and FlixBus.
There are 454+ hotels available in Isernia.









