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How to get fromPalermo to Iserniaby ferry, car, bus, train (Trenitalia), plane or train

Find Transport to Isernia

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There are 7 ways to get from Palermo to Isernia by ferry, car, bus, train (Trenitalia), plane, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Ferry, drive

    best
    1. Take the ferry from Port of Palermo to Port of Naplesferry ferry
    2. Drive from Port of Naples to Iserniacar car
    9h 56m
    €57–77

  2. Bus

    cheapest
    1. Take the bus from Palermo Terminal Bus to Napoli, Autostazione Metroparkbus bus Itabus
    2. Take the bus from Napoli, Autostazione Metropark to Iserniabus bus 6
    13h 30m
    €23–36

  3. Bus via Caserta

    1. Take the bus from Palermo Via Tommaso Fazello to Caserta Viale Vittorio Venetobus bus Autoservizi Salemi S202
    2. Take the bus from Caserta Terminal Bus to Iserniabus bus 433
    12h 4m
    €31–51

  4. Train

    1. Take the train from Palermo Centrale to Napoli Centraletrain train Ic
    2. Take the train from Napoli Centrale to Iserniatrain train Re
    12h 18m
    €30–100

  5. Fly Palermo Airport to Naples Airport, train

    1. Fly from Palermo Airport (PMO) to Naples Airport (NAP)plane plane PMO - NAP
    2. Take the train from Napoli Centrale to Iserniatrain train
    6h 4m
    €36–143

  6. Fly Palermo Airport to Fiumicino International Airport, train

    1. Fly from Palermo Airport (PMO) to Fiumicino International Airport (FCO)plane plane PMO - FCO
    2. Take the train from Roma Termini to Iserniatrain train
    6h 44m
    €53–188

  7. Bus to Catania–Fontanarossa Airport, fly to Naples Airport, train

    1. Take the bus from Palermo Via Tommaso Fazello to Catania Fontanarossa Airport Departure Terminalbus bus
    2. Fly from Catania–Fontanarossa Airport (CTA) to Naples Airport (NAP)plane plane CTA - NAP
    3. Take the train from Napoli Centrale to Iserniatrain train
    8h
    €43–167

Palermo to Isernia by bus

Calendar7Weekly Buses
Duration12h 4mAverage Duration
Ticket€31Cheapest Price
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Questions & Answers

What companies run services between Palermo, Italy and Isernia, Italy?

You can take a bus from Palermo Via Tommaso Fazello to Isernia via Caserta Viale Vittorio Veneto and Caserta Terminal Bus in around 12h 4m. Alternatively, you can take a train from Palermo Centrale to Isernia via Napoli Centrale in around 12h 18m.

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