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How to get fromPalermo to Iserniaby ferry, car, train, bus, plane, or train (Trenitalia)

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There are 10 ways to get from Palermo to Isernia by ferry, car, train, bus, plane, or train (Trenitalia)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Ferry, drive

    best
    1. Take the ferry from Port of Palermo to Naples Beverelloferry ferry
    2. Drive from Naples Beverello to Iserniacar car
    9h 58m
    €46–77

  2. Bus via Caserta

    cheapest
    1. Take the bus from Palermo Terminal Bus to Caserta pzza Garibaldibus bus Autoservizi Salemi S202
    2. Take the bus from Caserta Terminal Bus to Iserniabus bus 433
    12h 4m
    €37–54

  3. Train, ferry

    1. Take the train from Palermo Centrale to Messina Centraletrain train Re
    2. Take the ferry from Messina Marittima to Villa S.Giovanniferry ferry M1 / ...
    3. Take the train from Villa S.Giovanni to Napoli Afragolatrain train Fr
    4. Take the train from Napoli Afragola to Iserniatrain train Re
    11h 24m

  4. Fly Palermo Airport to Naples Airport, train

    1. Fly from Palermo Airport (PMO) to Naples Airport (NAP)plane plane PMO - NAP
    2. Take the train from Caserta to Iserniatrain train
    6h 26m
    €43–179

  5. Train (Trenitalia)

    1. Take the train from Palermo Centrale to Napoli Centraletrain train Ic
    2. Take the train from Napoli Centrale to Iserniatrain train Re
    12h 11m
    €86–170

  6. Bus

    1. Take the bus from Palermo Piazza Cairoli to Casello - A1 Ingresso Caianellobus bus
    2. Take the bus from Casello - A1 Ingresso Caianello to Iserniabus bus 6
    17h 54m

  7. Fly Palermo Airport to Fiumicino International Airport, train

    1. Fly from Palermo Airport (PMO) to Fiumicino International Airport (FCO)plane plane PMO - FCO
    2. Take the train from Roma Termini to Iserniatrain train
    6h 39m
    €51–163

  8. Bus to Trapani Airport, fly to Fiumicino International Airport, train

    1. Take the bus from Palermo Via Belgio/Via dei Nebrodi to Trapani Birgi Airportbus bus
    2. Fly from Trapani Airport (TPS) to Fiumicino International Airport (FCO)plane plane TPS - FCO
    3. Take the train from Roma Termini to Iserniatrain train
    7h 25m
    €74–226

  9. Bus to Catania–Fontanarossa Airport, fly to Naples Airport, train

    1. Take the bus from Palermo Via Tommaso Fazello to Catania Fontanarossa Airport Departure Terminalbus bus
    2. Fly from Catania–Fontanarossa Airport (CTA) to Naples Airport (NAP)plane plane CTA - NAP
    3. Take the train from Caserta to Iserniatrain train
    8h 22m
    €53–200

  10. Bus to Trapani Airport, fly to Abruzzo Airport, bus

    1. Take the bus from Palermo Via Belgio/Via dei Nebrodi to Trapani Birgi Airportbus bus
    2. Fly from Trapani Airport (TPS) to Abruzzo Airport (PSR)plane plane TPS - PSR
    3. Take the bus from Pescara to Iserniabus bus
    8h 36m
    €55–251

Palermo Airport (PMO) to Naples Airport (NAP) flights

Calendar25Weekly Planes
Duration1h 1mAverage Duration
Ticket€19Cheapest Price
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Questions & Answers

Map of how to get from Palermo to Isernia.ExpandLaunch map view
  • Distance: 418.2 km
  • Duration: 9h 58m

What companies run services between Palermo, Italy and Isernia, Italy?

You can take a bus from Palermo Terminal Bus to Isernia via Caserta pzza Garibaldi and Caserta Terminal Bus in around 12h 4m. Alternatively, you can take a train from Palermo Centrale to Isernia via Napoli Centrale in around 12h 11m.

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