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There are 6 ways to get from Naperville to St. Louis by train, plane, bus or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Train to Chicago O'Hare, fly  •  4 h 15 min

  1. Take the train from Naperville to Chicago Union Station
  2. Fly from Chicago O'Hare (ORD) to St. Louis (STL) ORD - STL

$97 - $256

Cheapest option

Train, bus  •  7 h 55 min

  1. Take the train from Naperville to Chicago Union Station Bnsf
  2. Take the bus from Chicago, IL to St. Louis via St Louis

$38 - $51

4 alternative options

Train to Chicago Midway, fly  •  4 h 12 min

  1. Take the train from Naperville to Chicago Union Station
  2. Fly from Chicago Midway (MDW) to St. Louis (STL) MDW - STL

$132 - $315

Train  •  7 h 4 min

  1. Take the train from Naperville to Chicago Union Station Bnsf
  2. Take the train from Chicago Union Station to St. Louis Gateway Station Lincoln Service / ...

$57 - $138

Bus  •  7 h 50 min

  1. Take the bus from Naperville Rt59 to Chicago, Il 4566 / ...
  2. Take the bus from Chicago, Il to St Louis, Mo 1353 / ...

$45 - $105

Drive  •  4 h 35 min

  1. Drive from Naperville to St. Louis 275.4 miles

$27 - $40

Questions & Answers

The cheapest way to get from Naperville to St. Louis is to drive which costs $27 - $40 and takes 4 h 35 min.

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The quickest way to get from Naperville to St. Louis is to train and fly which costs $130 - $320 and takes 4 h 12 min.

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No, there is no direct bus from Naperville to St. Louis. However, there are services departing from Naperville Rt59 and arriving at St Louis, Mo via Chicago, Il. The journey, including transfers, takes approximately 7 h 50 min.

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No, there is no direct train from Naperville to St. Louis station. However, there are services departing from Naperville and arriving at St. Louis Gateway Station via Chicago Union Station. The journey, including transfers, takes approximately 7 h 4 min.

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The distance between Naperville and St. Louis is 245 miles. The road distance is 275.4 miles.

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The best way to get from Naperville to St. Louis without a car is to train which takes 7 h 4 min and costs $55 - $140.

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It takes approximately 4 h 15 min to get from Naperville to St. Louis, including transfers.

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Naperville to St. Louis bus services, operated by Greyhound USA, depart from Naperville Rt59 station.

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Naperville to St. Louis train services, operated by Metra, depart from Naperville station.

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The best way to get from Naperville to St. Louis is to train which takes 7 h 4 min and costs $55 - $140. Alternatively, you can bus, which costs $45 - $110 and takes 7 h 50 min.

Mode details

Map of how to get from Naperville to St. Louis.
Launch map view
  • Distance: 245 miles
  • Duration: 4 h 15 min

What companies run services between Naperville, IL, USA and St. Louis, MO, USA?

You can take a train from Naperville to St. Louis via Chicago Union Station in around 7 h 4 min. Alternatively, you can take a bus from Naperville to St. Louis via Chicago, Il in around 7 h 50 min.

Airlines
Southwest Airlines
Website
southwest.com
Flights from Chicago Midway to St. Louis
Ave. Duration
1 h 7 min
When
Every day
Estimated price
$160 - $550
United Airlines
Website
united.com
Flights from Chicago O'Hare to St. Louis
Ave. Duration
1 h 23 min
When
Every day
Estimated price
$120 - $650
American Airlines
Website
aa.com
Flights from Chicago O'Hare to St. Louis
Ave. Duration
1 h 10 min
When
Every day
Estimated price
$120 - $550
Train operators
Metra
Phone
+1 312-322-6777
Website
metrarail.com
Train from Naperville to Chicago Union Station
Ave. Duration
34 min
Frequency
Hourly
Estimated price
$6 - $8
Schedules at
metrarail.com
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 215-856-7924
Website
amtrak.com
Train from Chicago Union Station to St. Louis Gateway Station
Ave. Duration
5 h 30 min
Frequency
Every 4 hours
Estimated price
$50 - $130
Website
amtrak.com
Coach Seat
$50 - $75
Flexi Coach Seat
$90 - $130
Business Coach Seat
$90 - $130
Room
$230 - $320
Bus operators
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Naperville Rt59 to Chicago, Il
Ave. Duration
1 h 5 min
Frequency
Twice daily
Estimated price
$10 - $21
Website
greyhound.com
Economy
$10 - $14
Flexible
$16 - $21
Bus from Chicago, Il to St Louis, Mo
Ave. Duration
5 h 45 min
Frequency
Every 4 hours
Estimated price
$35 - $85
Website
greyhound.com
Economy
$35 - $55
Flexible
$65 - $85

Want to know more about travelling around United States

Rome2rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

More Questions & Answers

The quickest flight from Chicago O'Hare Airport to St. Louis Airport is the direct flight which takes 1 h 5 min.

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Naperville to St. Louis bus services, operated by Greyhound USA, arrive at St Louis, Mo station.

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Naperville to St. Louis train services, operated by Amtrak, arrive at St. Louis Gateway Station.

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Yes, the driving distance between Naperville to St. Louis is 275 miles. It takes approximately 4 h 35 min to drive from Naperville to St. Louis.

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American Airlines and United Airlines offer flights from Chicago O'Hare Airport to St. Louis Airport.

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Book your Naperville to St. Louis bus tickets online with Greyhound and Greyhound.

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There are 198+ hotels available in St. Louis. Prices start at $69 USD per night.

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