There are 6 ways to get from Naperville to St. Louis by train, plane, bus or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Train to Chicago Midway, fly  •  4 h 14 min

  1. Take the train from Naperville to Chicago Union Station
  2. Fly from Chicago Midway (MDW) to St. Louis (STL) MDW - STL

$127 - $309

Cheapest option

Train, bus  •  7 h 3 min

  1. Take the train from Naperville to Chicago Union Station Bnsf
  2. Take the bus from Chicago, IL to St Louis, MO via St Louis

$32 - $43

4 alternative options

Train to Chicago O'Hare, fly  •  4 h 22 min

  1. Take the train from Naperville to Chicago Union Station
  2. Fly from Chicago O'Hare (ORD) to St. Louis (STL) ORD - STL

$92 - $250

Train  •  7 h 3 min

  1. Take the train from Naperville to Chicago Union Station Bnsf
  2. Take the train from Chicago Union Station Amtrak to St. Louis Gateway Station Amtrak Lincoln Service / ...

$53 - $133

Bus  •  7 h 20 min

  1. Take the bus from Naperville Rt59 to Chicago, Il 4566 / ...
  2. Take the bus from Chicago, Il to St Louis, Mo 1353

$45 - $105

Drive  •  4 h 35 min

  1. Drive from Naperville to St. Louis 275.4 miles

$27 - $40

What companies run services between Naperville, IL, USA and St. Louis, MO, USA?

You can take a train from Naperville to St. Louis via Chicago Union Station and Chicago Union Station Amtrak in around 7 h 3 min. Alternatively, you can take a bus from Naperville to St. Louis via Chicago, Il in around 7 h 20 min.

Airlines
Southwest Airlines
Website
southwest.com
Flights from Chicago Midway to St. Louis
Ave. Duration
1 h 5 min
When
Every day
Estimated price
$160 - $550
United Airlines
Website
united.com
Flights from Chicago O'Hare to St. Louis
Ave. Duration
1 h 21 min
When
Every day
Estimated price
$120 - $650
American Airlines
Website
aa.com
Flights from Chicago O'Hare to St. Louis
Ave. Duration
1 h 10 min
When
Every day
Estimated price
$120 - $550
Train operators
Metra
Phone
+1 312-322-6777
Website
metrarail.com
Train from Naperville to Chicago Union Station
Ave. Duration
33 min
Frequency
Every 2 hours
Estimated price
$2 - $3
Schedules at
metrarail.com
Amtrak
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Chicago Union Station Amtrak to St. Louis Gateway Station Amtrak
Ave. Duration
5 h 30 min
Frequency
Every 4 hours
Estimated price
$50 - $130
Website
amtrak.com
Coach Seat
$50 - $75
Flexi Coach Seat
$90 - $130
Business Coach Seat
$90 - $130
Room
$230 - $320
Bus operators
Greyhound USA
Phone
+1 214-849-8100
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Naperville Rt59 to Chicago, Il
Ave. Duration
1 h 5 min
Frequency
Hourly
Estimated price
$10 - $21
Website
greyhound.com
Economy
$10 - $14
Flexible
$16 - $21
Bus from Chicago, Il to St Louis, Mo
Ave. Duration
5 h 45 min
Frequency
Hourly
Estimated price
$35 - $85
Website
greyhound.com
Economy
$35 - $55
Flexible
$65 - $85

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Questions & Answers

The distance between Naperville and St. Louis is 392 km. The road distance is 441 km.

The cheapest way to get from Naperville to St. Louis is to drive which costs $27 - $40 and takes 4 h 35 min.

The quickest way to get from Naperville to St. Louis is to train and fly which takes 4 h 14 min and costs $120 - $310.

No, there is no direct train from Naperville to St. Louis. However, there are services departing from Naperville and arriving at St. Louis Gateway Station Amtrak via Chicago Union Station Amtrak. The journey, including transfers, takes approximately 7 h 3 min.

No, there is no direct bus from Naperville to St. Louis. However, there are services departing from Naperville Rt59 and arriving at St Louis, Mo via Chicago, Il. The journey, including transfers, takes approximately 7 h 20 min.

It takes approximately 4 h 14 min to get from Naperville to St. Louis, including transfers.