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How to get fromNaperville to St. Louisby train (Amtrak), bus (Flixbus), car, train or plane

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There are 6 ways to get from Naperville to St. Louis by train (Amtrak), bus (Flixbus), car, train, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Naperville to Chicago Union Stationtrain train Bnsf
    2. Take the train from Chicago Union Station to St. Louistrain train Lincoln Service / ...
    6h 50m
    $40–206

  2. Bus

    1. Take the bus from Oakbrook Mall to Illinois Terminalbus bus Chicago to Champaign via shopping SB / ...
    2. Take the bus from Champaign Intermodal Trans Ctr to St Louis Bus Stationbus bus FlixBus N2521 / ...
    9h 7m
    $78–114

  3. Drive 273.8 mi

    1. Drive from Naperville to St. Louiscar car 273.8 mi
    4h 36m
    $50–73

  4. Train to Chicago Midway International Airport, fly

    1. Take the train from Naperville to Chicago Union Stationtrain train
    2. Fly from Chicago Midway International Airport (MDW) to Lambert–St. Louis International Airport (STL)plane plane MDW - STL
    4h 57m
    $95–614

  5. Train to Chicago O'Hare International Airport, fly

    1. Take the train from Naperville to Chicago Union Stationtrain train
    2. Fly from Chicago O'Hare International Airport (ORD) to Lambert–St. Louis International Airport (STL)plane plane ORD - STL
    5h 12m
    $210–504

  6. Train, train to General Mitchell International Airport, fly

    1. Take the train from Naperville to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Milwaukeetrain train
    3. Fly from General Mitchell International Airport (MKE) to Lambert–St. Louis International Airport (STL)plane plane MKE - STL
    7h 10m
    $152–929

Naperville to St. Louis by train

Calendar38Weekly Trains
Duration6h 50mAverage Duration
Ticket$40Cheapest Price
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Questions & Answers

What companies run services between Naperville, IL, USA and St. Louis, MO, USA?

You can take a train from Naperville to St. Louis via Chicago Union Station in around 6h 50m. Alternatively, you can take a bus from Washington St & Ogden Ave to St Louis Bus Station via Yorktown Center, Oakbrook Mall, Illinois Terminal, and Champaign Intermodal Trans Ctr in around 9h 7m.

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