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How to get fromSeattle to St. Louisby plane, bus (Flixbus, Greyhound), train (Amtrak), car, bus or train

Find Transport to St. Louis

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There are 6 ways to get from Seattle to St. Louis by plane, bus (Flixbus, Greyhound), train (Amtrak), car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Seattle-Tacoma International Airport

    best
    1. Fly from Seattle-Tacoma International Airport (SEA) to Lambert–St. Louis International Airport (STL)planeSEA - STL
    6h 25m
    $192–810

  2. Bus

    1. Take the bus from Seattle Bus Station to Spokane Stationbus
    2. Take the bus from Spokane to Billingsbus
    3. Take the bus from Billings, MT to Cheyenne, WYbus
    4. Take the bus from Cheyenne to Denver Union Stationbus
    5. Take the bus from Denver Union Station to St Louis Bus Stationbus
    47h 5m
    $327–699

  3. Train (Amtrak)

    1. Take the train from Seattle to Chicago Union StationtrainEmpire Builder
    2. Take the train from Chicago Union Station to St. LouistrainLincoln Service / ...
    2d 3h
    $276–2,253

  4. Drive 2,078.8 mi

    1. Drive from Seattle to St. Louiscar2,078.8 mi
    32h 55m
    $380–548

  5. Bus to Bellingham International Airport, fly

    1. Take the bus from Seattle, WA - Convention centre to Bellingham Airportbus
    2. Fly from Bellingham International Airport (BLI) to Lambert–St. Louis International Airport (STL)planeBLI - STL
    9h 35m
    $243–939

  6. Train to Portland International Airport, fly

    1. Take the train from Seattle to Portlandtrain
    2. Fly from Portland International Airport (PDX) to Lambert–St. Louis International Airport (STL)planePDX - STL
    9h 45m
    $287–1,183

Seattle to St. Louis by bus

Calendar1Weekly Buses
Duration47h 5mAverage Duration
Ticket$327Cheapest Price
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Questions & Answers

What companies run services between Seattle, WA, USA and St. Louis, MO, USA?

Alaska Airlines, Inc., Southwest Airlines, and two other airlines fly from Seattle-Tacoma International Airport (SEA) to Lambert–St. Louis International Airport (STL) every 2 hours. Alternatively, you can take a bus from Seattle Bus Station to St Louis Bus Station via Spokane, Billings, Billings, MT, Cheyenne, and Denver Union Station in around 47h 5m.

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