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How to get fromSeattle to St. Louisby plane, bus (Flixbus, Greyhound), train (Amtrak), car, bus or train

Find Transport to St. Louis

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There are 7 ways to get from Seattle to St. Louis by plane, bus (Flixbus, Greyhound), train (Amtrak), car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Seattle-Tacoma International Airport

    best
    1. Fly from Seattle-Tacoma International Airport (SEA) to Lambert–St. Louis International Airport (STL)plane plane SEA - STL
    6h 27m
    $239–1,109

  2. Bus

    1. Take the bus from Seattle Bus Station to Spokane Stationbus bus
    2. Take the bus from Spokane to Billingsbus bus
    3. Take the bus from Billings, MT to Cheyenne, WYbus bus
    4. Take the bus from Cheyenne to Denver Union Stationbus bus
    5. Take the bus from Denver Union Station to St Louis Bus Stationbus bus
    47h 5m
    $339–797

  3. Train (Amtrak)

    1. Take the train from Seattle to Chicago Union Stationtrain train Empire Builder
    2. Take the train from Chicago Union Station to St. Louistrain train Lincoln Service / ...
    2d 3h
    $248–764

  4. Drive 2,078.8 mi

    1. Drive from Seattle to St. Louiscar car 2,078.8 mi
    33h 3m
    $380–548

  5. Bus to Bellingham International Airport, fly

    1. Take the bus from Seattle, WA - Convention centre to Bellingham Airportbus bus
    2. Fly from Bellingham International Airport (BLI) to Lambert–St. Louis International Airport (STL)plane plane BLI - STL
    10h 27m
    $293–1,239

  6. Fly from Paine Field County Airport

    1. Fly from Paine Field County Airport (PAE) to Lambert–St. Louis International Airport (STL)plane plane PAE - STL
    9h 10m
    $320–1,329

  7. Train to Portland International Airport, fly

    1. Take the train from Seattle to Portlandtrain train
    2. Fly from Portland International Airport (PDX) to Lambert–St. Louis International Airport (STL)plane plane PDX - STL
    9h 44m
    $357–1,581

Seattle to St. Louis by bus

Calendar1Weekly Buses
Duration47h 5mAverage Duration
Ticket$339Cheapest Price
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Questions & Answers

What companies run services between Seattle, WA, USA and St. Louis, MO, USA?

Alaska Airlines, Inc., Southwest Airlines, and two other airlines fly from Seattle-Tacoma International Airport (SEA) to Lambert–St. Louis International Airport (STL) every 4 hours. Alternatively, you can take a bus from Seattle Bus Station to St Louis Bus Station via Spokane, Billings, Billings, MT, Cheyenne, and Denver Union Station in around 47h 5m.

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