There are 6 ways to get from Myrtle Beach to Tupelo by plane, car, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Golden Triangle Regional Airport, drive
best- Fly from Myrtle Beach (MYR) to Golden Triangle Regional Airport (GTR)plane MYR - GTR
- Drive from Golden Triangle Regional Airport (GTR) to Tupelocar
8h 22m$81–379Bus (Greyhound)
- Take the bus from Myrtle Beach Bus Station to Atlanta Bus Stationbus Greyhound US0641
- Take the bus from Atlanta Bus Station to Tupelobus Greyhound US0610
15h 44m$102–202Drive 624.8 mi
- Drive from Myrtle Beach to Tupelocar 624.8 mi
11h 9m$114–165Fly to Huntsville International Airport-Carl T Jones Field, drive
- Fly from Myrtle Beach (MYR) to Huntsville International Airport-Carl T Jones Field (HSV)plane MYR - HSV
- Drive from Huntsville International Airport-Carl T Jones Field (HSV) to Tupelocar
5h 49m$108–497Fly to Tupelo Regional Airport
- Fly from Myrtle Beach (MYR) to Tupelo Regional Airport (TUP)plane MYR - TUP
7h 12m$126–632Bus via Columbia
- Take the bus from Myrtle Beach, SC to Columbiabus
- Take the bus from Columbia to Atlantabus
- Take the bus from Atlanta Bus Station to Tupelobus
16h 5m$165–341
Myrtle Beach (MYR) to Golden Triangle Regional Airport (GTR) flights
Questions & Answers
The cheapest way to get from Myrtle Beach to Tupelo is to drive which costs $110 - $170 and takes 11h 9m.
The fastest way to get from Myrtle Beach to Tupelo is to fly and drive which takes 5h 49m and costs $100 - $500.
The distance between Myrtle Beach and Tupelo is 625 miles. The road distance is 628.5 miles.
The best way to get from Myrtle Beach to Tupelo without a car is to bus which takes 15h 44m and costs $100 - $210.
It takes approximately 8h 22m to get from Myrtle Beach to Tupelo, including transfers.
The best way to get from Myrtle Beach to Tupelo is to bus which takes 15h 44m and costs $100 - $210. Alternatively, you can fly, which costs $120 - $650 and takes 7h 12m.
Tupelo is 1h behind Myrtle Beach. It is currently 5:49 PM in Myrtle Beach and 4:49 PM in Tupelo.
Yes, the driving distance between Myrtle Beach to Tupelo is 628 miles. It takes approximately 11h 9m to drive from Myrtle Beach to Tupelo.
There are 33+ hotels available in Tupelo.
What companies run services between Myrtle Beach, SC, USA and Tupelo, MS, USA?
You can take a bus from Myrtle Beach Bus Station to Tupelo via Atlanta Bus Station and Tupelo in around 15h 44m. Alternatively, Southwest Airlines, Corporate Flight Management Inc, and two other airlines fly from Myrtle Beach (MYR) to Tupelo Regional Airport (TUP) once daily.
- Website
- delta.com
Flights from Myrtle Beach to Golden Triangle Regional Airport via Atlanta
- Ave. Duration
- 8h 35m
- When
- Every day
- Estimated price
- $60–350
Flights from Myrtle Beach to Huntsville International Airport-Carl T Jones Field via Atlanta
- Ave. Duration
- 4h 10m
- When
- Every day
- Estimated price
- $75–450
- Website
- aa.com
Flights from Myrtle Beach to Huntsville International Airport-Carl T Jones Field via Charlotte
- Ave. Duration
- 4h 53m
- When
- Every day
- Estimated price
- $75–460
Flights from Myrtle Beach to Huntsville International Airport-Carl T Jones Field via Chicago O'Hare
- Ave. Duration
- 5h 41m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $130–650
Flights from Myrtle Beach to Huntsville International Airport-Carl T Jones Field via Reagan Washington
- Ave. Duration
- 6h 40m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $110–600
- Website
- contouraviation.com
Flights from Myrtle Beach to Tupelo Regional Airport via Nashville
- Ave. Duration
- 9h 15m
- When
- Sunday
- Estimated price
- $100–600
Flights from Myrtle Beach to Tupelo Regional Airport via Charlotte, Nashville
- Ave. Duration
- 8h 12m
- When
- Every day
- Estimated price
- $100–600
Flights from Myrtle Beach to Tupelo Regional Airport via Atlanta, Nashville
- Ave. Duration
- 9h 12m
- When
- Sunday
- Estimated price
- $100–600
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Myrtle Beach Bus Station to Atlanta Bus Station
- Ave. Duration
- 8h 55m
- Frequency
- Once daily
- Estimated price
- $40–70
- Website
- https://www.greyhound.com/
Bus from Atlanta Bus Station to Tupelo
- Ave. Duration
- 5h 45m
- Frequency
- Twice daily
- Estimated price
- $50–120
- Website
- https://www.greyhound.com/
- Phone
- +1 404-591-2750
- info@southeasternstages.com
- Website
- southeasternstages.com
Bus from Myrtle Beach, SC to Columbia
- Ave. Duration
- 3h 45m
- Frequency
- Once daily
- Estimated price
- $45–100
- Schedules at
- southeasternstages.com
Bus from Columbia to Atlanta
- Ave. Duration
- 4h 31m
- Frequency
- 4 times a day
- Estimated price
- $60–110
- Schedules at
- southeasternstages.com
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