There are 7 ways to get from Springfield to Tupelo by bus (Flixbus, Greyhound), car, plane, bus, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Springfield SMTD Transfer Center to Memphis Bus Stationbus FlixBus 2510
- Take the bus from Memphis Bus Station to Tupelobus Greyhound US0610
9h 34m$73–135Drive 436.1 mi
- Drive from Springfield to Tupelocar 436.1 mi
8h 49m$80–115Fly Abraham Lincoln Capital Airport to Memphis, bus
- Fly from Abraham Lincoln Capital Airport (SPI) to Memphis (MEM)plane SPI - MEM
- Take the bus from Memphis Bus Station to Tupelobus
9h 21m$142–659Train, bus
- Take the train from Springfield to St. Louistrain
- Take the bus from St Louis Bus Station to Memphis Bus Stationbus
- Take the bus from Memphis Bus Station to Tupelobus
11h 2m$77–155Train to Lambert–St. Louis International Airport, fly to Tupelo Regional Airport
- Take the train from Springfield to St. Louistrain
- Fly from Lambert–St. Louis International Airport (STL) to Tupelo Regional Airport (TUP)plane STL - TUP
7h 29m$154–822Bus to Nashville, fly to Tupelo Regional Airport
- Take the bus from Springfield SMTD Transfer Center to Nashville Bus Stationbus
- Fly from Nashville (BNA) to Tupelo Regional Airport (TUP)plane BNA - TUP
10h 56m$137–522Train to Lambert–St. Louis International Airport, fly to Jonesboro Municipal Airport, bus
- Take the train from Springfield to St. Louistrain
- Fly from Lambert–St. Louis International Airport (STL) to Jonesboro Municipal Airport (JBR)plane STL - JBR
- Take the bus from Jonesboro to Memphis Bus Stationbus
- Take the bus from Memphis Bus Station to Tupelobus
10h 26m$283–867
Abraham Lincoln Capital Airport (SPI) to Memphis (MEM) flights
Questions & Answers
The cheapest way to get from Springfield to Tupelo is to drive which costs $75 - $120 and takes 8h 49m.
The fastest way to get from Springfield to Tupelo is to train and fly which takes 7h 29m and costs $150 - $850.
The distance between Springfield and Tupelo is 495 miles. The road distance is 438.6 miles.
The best way to get from Springfield to Tupelo without a car is to bus which takes 9h 34m and costs $70 - $140.
It takes approximately 9h 34m to get from Springfield to Tupelo, including transfers.
Yes, the driving distance between Springfield to Tupelo is 439 miles. It takes approximately 8h 49m to drive from Springfield to Tupelo.
There are 34+ hotels available in Tupelo.
What companies run services between Springfield, IL, USA and Tupelo, MS, USA?
You can take a bus from Springfield SMTD Transfer Center to Tupelo via Memphis Bus Station and Tupelo in around 9h 34m.
- Website
- contouraviation.com
Flights from Lambert–St. Louis International Airport to Tupelo Regional Airport via Nashville
- Ave. Duration
- 4h
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $120–750
Flights from Lambert–St. Louis International Airport to Tupelo Regional Airport via Dallas/Ft.Worth
- Ave. Duration
- 5h 54m
- When
- Every day
- Estimated price
- $190–1,000
Flights from Lambert–St. Louis International Airport to Tupelo Regional Airport via Atlanta, Nashville
- Ave. Duration
- 6h 35m
- When
- Every day
- Estimated price
- $170–950
Flights from Lambert–St. Louis International Airport to Tupelo Regional Airport via Chicago Midway, Nashville
- Ave. Duration
- 8h
- When
- Sunday
- Estimated price
- $170–900
Flights from Nashville to Tupelo Regional Airport
- Ave. Duration
- 1h 5m
- When
- Every day
- Estimated price
- $65–260
- Website
- aa.com
Flights from Abraham Lincoln Capital Airport to Memphis via Chicago O'Hare
- Ave. Duration
- 5h 29m
- When
- Every day
- Estimated price
- $100–600
- Website
- iflysouthern.com
Flights from Lambert–St. Louis International Airport to Jonesboro Municipal Airport
- Ave. Duration
- 1h 31m
- When
- Every day
- Estimated price
- $200–700
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Springfield to St. Louis
- Ave. Duration
- 1h 48m
- Frequency
- 5 times a day
- Estimated price
- $15–50
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Springfield SMTD Transfer Center to Memphis Bus Station
- Ave. Duration
- 6h 50m
- Frequency
- 5 times a week
- Estimated price
- $45–95
- Schedules at
- flixbus.com
- Adult
- $45–95
Bus from St Louis Bus Station to Memphis Bus Station
- Ave. Duration
- 4h 45m
- Frequency
- 5 times a week
- Estimated price
- $40–60
- Schedules at
- flixbus.com
Bus from Springfield SMTD Transfer Center to Nashville Bus Station
- Ave. Duration
- 8h
- Frequency
- Once daily
- Estimated price
- $50–120
- Schedules at
- flixbus.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Memphis Bus Station to Tupelo
- Ave. Duration
- 1h 40m
- Frequency
- Twice daily
- Estimated price
- $17–29
- Website
- https://www.greyhound.com/
Bus from St Louis Bus Station to Memphis Bus Station
- Ave. Duration
- 5h 30m
- Frequency
- Once daily
- Estimated price
- $35–65
- Website
- https://www.greyhound.com/
Bus from Jonesboro to Memphis Bus Station
- Ave. Duration
- 1h 35m
- Frequency
- Once daily
- Estimated price
- $27–60
- Website
- https://www.greyhound.com/
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide









