There are 6 ways to get from Natchez to Tupelo by car, train, bus, plane, or taxi
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Drive, train, bus
best- Drive from Natchez to Brookhaven Amtrak Station
- Take the train from Brookhaven Amtrak Station to Jackson
- Take the bus from Jackson to Memphis Bus Station
- Take the bus from Memphis Bus Station to Tupelo
10h 15m$80–229Drive 265.6 mi
cheapest- Drive from Natchez to Tupelo265.6 mi
6h 20m$49–70Fly Natchez to Memphis, bus
- Fly from Natchez (HEZ) to Memphis (MEM)HEZ - MEM
- Take the bus from Memphis Bus Station to Tupelo
8h 18m$155–656Taxi to Alexandria International Airport, fly to Tupelo Regional Airport
- Take the taxi from Natchez to Alexandria International Airport (AEX)
- Fly from Alexandria International Airport (AEX) to Tupelo Regional Airport (TUP)AEX - TUP
6h 19m$138–596Drive to Baton Rouge Metropolitan Airport, fly to Tupelo Regional Airport
- Drive from Natchez to Baton Rouge Metropolitan Airport (BTR)
- Fly from Baton Rouge Metropolitan Airport (BTR) to Tupelo Regional Airport (TUP)BTR - TUP
6h 32m$126–592Taxi to Monroe Regional Airport, fly to Tupelo Regional Airport
- Take the taxi from Natchez to Monroe Regional Airport (MLU)
- Fly from Monroe Regional Airport (MLU) to Tupelo Regional Airport (TUP)MLU - TUP
6h 35m$133–596
Natchez (HEZ) to Memphis (MEM) flights
Questions & Answers
The cheapest way to get from Natchez to Tupelo is to drive which costs $45 - $70 and takes 6h 20m.
The fastest way to get from Natchez to Tupelo is to taxi and fly which takes 6h 19m and costs $130 - $600.
The distance between Natchez and Tupelo is 435 miles. The road distance is 267.2 miles.
It takes approximately 10h 15m to get from Natchez to Tupelo, including transfers.
Yes, the driving distance between Natchez to Tupelo is 267 miles. It takes approximately 6h 20m to drive from Natchez to Tupelo.
There are 40+ hotels available in Tupelo.
What companies run services between Natchez, MS, USA and Tupelo, MS, USA?
There is no direct connection from Natchez to Tupelo. However, you can drive to Brookhaven Amtrak Station, take the train to Jackson, walk to Jackson, take the bus to Memphis Bus Station, take the bus to Tupelo, then take the taxi to Tupelo. Alternatively, you can drive from Natchez to Tupelo in around 6h 20m.
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- Website
- contouraviation.com
Flights from Alexandria International Airport to Tupelo Regional Airport via Dallas/Ft.Worth
- Ave. Duration
- 7h 13m
- When
- Every day
- Estimated price
- $160–850
Flights from Alexandria International Airport to Tupelo Regional Airport via Atlanta, Nashville
- Ave. Duration
- 6h 34m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $100–550
Flights from Alexandria International Airport to Tupelo Regional Airport via Dallas/Ft.Worth, Nashville
- Ave. Duration
- 7h 38m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $110–600
Flights from Alexandria International Airport to Tupelo Regional Airport via Houston, Nashville
- Ave. Duration
- 7h 5m
- When
- Monday to Saturday
- Estimated price
- $110–550
Flights from Baton Rouge Metropolitan Airport to Tupelo Regional Airport via Dallas/Ft.Worth
- Ave. Duration
- 7h 15m
- When
- Every day
- Estimated price
- $170–950
Flights from Baton Rouge Metropolitan Airport to Tupelo Regional Airport via Atlanta, Nashville
- Ave. Duration
- 7h 17m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $95–550
Flights from Baton Rouge Metropolitan Airport to Tupelo Regional Airport via Houston, Nashville
- Ave. Duration
- 8h 14m
- When
- Every day
- Estimated price
- $110–600
Flights from Monroe Regional Airport to Tupelo Regional Airport via Dallas/Ft.Worth
- Ave. Duration
- 7h 28m
- When
- Every day
- Estimated price
- $160–850
Flights from Monroe Regional Airport to Tupelo Regional Airport via Atlanta, Nashville
- Ave. Duration
- 6h 19m
- When
- Monday to Friday
- Estimated price
- $95–550
Flights from Monroe Regional Airport to Tupelo Regional Airport via Dallas/Ft.Worth, Nashville
- Ave. Duration
- 7h 58m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $110–600
- Website
- united.com
Flights from Natchez to Memphis via Houston
- Ave. Duration
- 5h 46m
- When
- Every day
- Estimated price
- $95–550
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Brookhaven Amtrak Station to Jackson
- Ave. Duration
- 1h 32m
- Frequency
- Once daily
- Estimated price
- $7–60
- Website
- https://www.amtrak.com/home.html
- Coach Seat - Advance Purchase
- $16–27
- Coach Seat short notice purchase
- $7–60
- Business - advance purchase
- $9–80
- Business Class
- $16–170
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Jackson to Memphis Bus Station
- Ave. Duration
- 3h 25m
- Frequency
- Once daily
- Estimated price
- $30–80
- Website
- https://www.greyhound.com/
Bus from Memphis Bus Station to Tupelo
- Ave. Duration
- 1h 45m
- Frequency
- Twice daily
- Estimated price
- $21–60
- Website
- https://www.greyhound.com/
- Ave. Duration
- 1h 57m
- Estimated price
- $22–26
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