There are 8 ways to get from Myrtle Beach to Mesa by plane, bus (Greyhound, Flixbus), bus, train, car, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Myrtle Beach
best- Fly from Myrtle Beach (MYR) to Phoenix (PHX)plane MYR - PHX
7h 36m$172–764Bus
- Take the bus from Myrtle Beach Bus Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to St Louis Bus Stationbus
- Take the bus from St Louis Bus Station to Phoenix Bus Stationbus
2d 4h$377–681Bus, train via New Orleans
- Take the bus from Myrtle Beach Bus Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to New Orleans Bus Stationbus
- Take the train from New Orleans Union Passenger Terminal to Tucson Amtrak Stationtrain
- Take the bus from Tucson Downtown to Tempebus
2d 12h$479–1,083Drive 2,137.1 mi
- Drive from Myrtle Beach to Mesacar 2,137.1 mi
35h 2m$390–564Bus to Florence Regional Airport, fly
- Take the bus from Myrtle Beach Bus Station to Florence Bus Stationbus
- Fly from Florence Regional Airport (FLO) to Phoenix (PHX)plane FLO - PHX
10h 43m$183–785Bus to Wilmington International Airport, fly
- Take the bus from Myrtle Beach Bus Station to Wilmington Cape Fear Public Transitbus
- Fly from Wilmington International Airport (ILM) to Phoenix (PHX)plane ILM - PHX
10h 41m$199–843Bus via Irving (Greyhound)
- Take the bus from Myrtle Beach Bus Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Dallas Bus Stationbus
- Take the bus from Dallas Bus Station to Phoenix Bus Stationbus
2d 5h$364–684Bus, train
- Take the bus from Myrtle Beach Bus Station to Charleston Bus Stationbus
- Take the train from Charleston Amtrak Station to Petersburg Amtrak Stationtrain
- Take the train from Petersburg Amtrak Station to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Flagstafftrain
- Take the bus from Flagstaff Train Station to Phoenix Sky Harbor Airport/44th Street Sky Train Stationbus
2d 21h$685–1,621
Myrtle Beach to Mesa by bus and tram
Questions & Answers
The cheapest way to get from Myrtle Beach to Mesa is to fly which costs $170 - $800 and takes 7h 36m.
The fastest way to get from Myrtle Beach to Mesa is to fly which takes 7h 36m and costs $170 - $800.
No, there is no direct bus from Myrtle Beach station to Mesa. However, there are services departing from Myrtle Beach Bus Station and arriving at University Dr & Mesa Dr via Atlanta Bus Station, Dallas Bus Station, Phoenix Bus Station, Phoenix Sky Harbor Airport/44th Street Sky Train Station and University Dr & Rural Rd. The journey, including transfers, takes approximately 2 days 5h.
The distance between Myrtle Beach and Mesa is 1923 miles. The road distance is 2149.6 miles.
The best way to get from Myrtle Beach to Mesa without a car is to bus which takes 2 days 4h and costs $370 - $700.
It takes approximately 7h 36m to get from Myrtle Beach to Mesa, including transfers.
Myrtle Beach to Mesa bus services, operated by Greyhound USA, depart from Myrtle Beach Bus Station.
The best way to get from Myrtle Beach to Mesa is to fly which takes 7h 36m and costs $170 - $800. Alternatively, you can bus, which costs $370 - $700 and takes 2 days 4h.
Myrtle Beach to Mesa bus services, operated by Greyhound USA, arrive at Atlanta Bus Station.
Mesa is 2h behind Myrtle Beach. It is currently 5:34 PM in Myrtle Beach and 3:34 PM in Mesa.
What companies run services between Myrtle Beach, SC, USA and Mesa, AZ, USA?
Delta and Southwest Airlines fly from Myrtle Beach (MYR) to Phoenix (PHX) 5 times a day. Alternatively, you can take a bus from Myrtle Beach Bus Station to Mesa Dr/Main St via Atlanta Bus Station, St Louis Bus Station, Phoenix, Bus Station (E Buckeye Rd), 24th St Station, Phoenix Sky Harbor Airport/44th Street Sky Train Station, and 44th St/Washington in around 2d 4h.
- Website
- delta.com
Flights from Myrtle Beach to Phoenix via Atlanta
- Ave. Duration
- 7h 26m
- When
- Every day
- Estimated price
- $160–750
Flights from Wilmington International Airport to Phoenix via Atlanta
- Ave. Duration
- 8h 13m
- When
- Every day
- Estimated price
- $170–800
Flights from Wilmington International Airport to Phoenix via Minneapolis
- Ave. Duration
- 8h 17m
- When
- Saturday and Sunday
- Estimated price
- $200–900
- Website
- aa.com
Flights from Florence Regional Airport to Phoenix via Charlotte
- Ave. Duration
- 7h 26m
- When
- Every day
- Estimated price
- $160–750
Flights from Wilmington International Airport to Phoenix via Charlotte
- Ave. Duration
- 7h 28m
- When
- Every day
- Estimated price
- $170–800
Flights from Wilmington International Airport to Phoenix via Dallas/Ft.Worth
- Ave. Duration
- 7h 40m
- When
- Every day
- Estimated price
- $180–800
- Website
- southwest.com
Flights from Myrtle Beach to Phoenix via Nashville
- Ave. Duration
- 7h 51m
- When
- Monday to Saturday
- Estimated price
- $170–750
Flights from Myrtle Beach to Phoenix via Dallas
- Ave. Duration
- 8h 10m
- When
- Sunday
- Estimated price
- $170–750
Flights from Myrtle Beach to Phoenix via Houston Hobby Apt
- Ave. Duration
- 8h 15m
- When
- Saturday
- Estimated price
- $170–800
Flights from Myrtle Beach to Phoenix via Kansas City
- Ave. Duration
- 9h 45m
- When
- Saturday
- Estimated price
- $170–800
Flights from Myrtle Beach to Phoenix via St. Louis
- Ave. Duration
- 10h 20m
- When
- Saturday
- Estimated price
- $170–800
- Website
- united.com
Flights from Wilmington International Airport to Phoenix via Denver
- Ave. Duration
- 7h 21m
- When
- Saturday
- Estimated price
- $190–850
- Website
- suncountry.com
Flights from Wilmington International Airport to Phoenix via Minneapolis
- Ave. Duration
- 8h 12m
- When
- Thursday
- Estimated price
- $200–900
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from New Orleans Union Passenger Terminal to Tucson Amtrak Station
- Ave. Duration
- 37h
- Frequency
- 3 times a week
- Estimated price
- $330–800
- Website
- https://www.amtrak.com/home.html
Train from Charleston Amtrak Station to Petersburg Amtrak Station
- Ave. Duration
- 6h 16m
- Frequency
- Twice daily
- Estimated price
- $80–190
- Website
- https://www.amtrak.com/home.html
Train from Petersburg Amtrak Station to Chicago Union Station
- Ave. Duration
- 21h 50m
- Frequency
- Once daily
- Estimated price
- $200–470
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to Flagstaff
- Ave. Duration
- 31h 44m
- Frequency
- Twice daily
- Estimated price
- $370–900
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Myrtle Beach Bus Station to Atlanta Bus Station
- Ave. Duration
- 8h 55m
- Frequency
- Once daily
- Estimated price
- $60–110
- Website
- https://www.greyhound.com/
Bus from St Louis Bus Station to Phoenix Bus Station
- Ave. Duration
- 30h
- Frequency
- Twice daily
- Estimated price
- $250–460
- Website
- https://www.greyhound.com/
Bus from Atlanta Bus Station to New Orleans Bus Station
- Ave. Duration
- 9h 15m
- Frequency
- 3 times a day
- Estimated price
- $75–150
- Website
- https://www.greyhound.com/
Bus from Myrtle Beach Bus Station to Florence Bus Station
- Ave. Duration
- 1h 40m
- Frequency
- Once daily
- Estimated price
- $11–21
- Website
- https://www.greyhound.com/
Bus from Myrtle Beach Bus Station to Wilmington Cape Fear Public Transit
- Ave. Duration
- 1h 40m
- Frequency
- Once daily
- Estimated price
- $12–23
- Website
- https://www.greyhound.com/
Bus from Atlanta Bus Station to Dallas Bus Station
- Ave. Duration
- 17h 55m
- Frequency
- 3 times a day
- Estimated price
- $130–250
- Website
- https://www.greyhound.com/
Bus from Dallas Bus Station to Phoenix Bus Station
- Ave. Duration
- 21h 10m
- Frequency
- Twice daily
- Estimated price
- $170–320
- Website
- https://www.greyhound.com/
Bus from Myrtle Beach Bus Station to Charleston Bus Station
- Ave. Duration
- 2h 25m
- Frequency
- Once daily
- Estimated price
- $16–30
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Atlanta Bus Station to St Louis Bus Station
- Ave. Duration
- 10h 40m
- Frequency
- Once daily
- Estimated price
- $65–110
- Schedules at
- flixbus.com
Bus from Tucson Downtown to Tempe
- Ave. Duration
- 1h 50m
- Frequency
- 5 times a day
- Estimated price
- $12–22
- Schedules at
- flixbus.com
Bus from Flagstaff Train Station to Phoenix Sky Harbor Airport/44th Street Sky Train Station
- Ave. Duration
- 2h 25m
- Frequency
- Once daily
- Estimated price
- $17–30
- Schedules at
- flixbus.com
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
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More Questions & Answers
Yes, the driving distance between Myrtle Beach to Mesa is 2150 miles. It takes approximately 35h 2m to drive from Myrtle Beach to Mesa.
There are 2691+ hotels available in Mesa.








