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How to get fromMuscatine to St. Louisby car, bus, train, taxi or plane

Find Transport to St. Louis

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There are 4 ways to get from Muscatine to St. Louis by car, bus, train, taxi, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive, bus, train (Amtrak)

    best
    1. Drive from Muscatine to Galesburg Amtrak Stationcar car
    2. Take the bus from Galesburg Amtrak Station to Springfieldbus bus
    3. Take the train from Springfield to St. Louistrain train
    6h 39m

  2. Drive 233.8 mi

    cheapest
    1. Drive from Muscatine to St. Louiscar car 233.8 mi
    5h 33m
    $43–62

  3. Taxi, fly

    1. Take the taxi from Muscatine to Moline-Airport-MLItaxi taxi
    2. Fly from Quad City International Airport (MLI) to Lambert–St. Louis International Airport (STL)plane plane MLI - STL
    5h 10m
    $162–640

  4. Drive, bus

    1. Drive from Muscatine to Galesburg Amtrak Stationcar car
    2. Take the bus from Galesburg Amtrak Station to Springfieldbus bus
    3. Take the bus from Springfield SMTD Transfer Center to St Louis Bus Stationbus bus
    6h 57m

Quad City International Airport (MLI) to Lambert–St. Louis International Airport (STL) flights

Calendar56Weekly Planes
Duration5h 27mAverage Duration
Ticket$85Cheapest Price
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Questions & Answers

What companies run services between Muscatine, IA, USA and St. Louis, MO, USA?

There is no direct connection from Muscatine to St. Louis. However, you can drive to Galesburg Amtrak Station, take the bus to Springfield, walk to Springfield, then take the train to St. Louis. Alternatively, you can drive from Muscatine to St. Louis in around 5h 33m.

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