There are 6 ways to get from Memphis to St. Louis by bus, train, car or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Bus  •  5 h 30 min

  1. Take the bus from Memphis, TN to St. Louis 1143

$27 - $80

5 alternative options

Train, bus  •  7 h 2 min

  1. Take the train from Memphis Central Station to Carbondale Amtrak City Of New Orleans
  2. Take the bus from Carbondale to St Louis, Mo 4700 / ...

$59 - $142

Drive  •  4 h 38 min

  1. Drive from Memphis to St. Louis 285.3 miles

$27 - $45

Bus to Jonesboro, fly  •  4 h 47 min

  1. Take the bus from Memphis, Tn to Jonesboro, Ar
  2. Fly from Jonesboro (JBR) to St. Louis (STL) JBR - STL

$91 - $193

Fly from Memphis  •  6 h 1 min

  1. Fly from Memphis (MEM) to St. Louis (STL) MEM - STL

$195 - $955

Bus to Little Rock, fly  •  6 h 27 min

  1. Take the bus from Memphis, Tn to Little Rock, Ar
  2. Fly from Little Rock (LIT) to St. Louis (STL) LIT - STL

$216 - $951

Questions & Answers

Yes, there is a direct bus departing from Memphis, TN and arriving at St. Louis. Services depart every three hours, and operate every day. The journey takes approximately 5 h 30 min.

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The distance between Memphis and St. Louis is 242 miles. The road distance is 285.3 miles.

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The best way to get from Memphis to St. Louis without a car is to bus which takes 5 h 30 min and costs .

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The bus from Memphis, TN to St. Louis takes 5 h 30 min including transfers and departs every three hours.

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Memphis to St. Louis bus services, operated by Megabus, depart from Memphis, TN station.

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The best way to get from Memphis to St. Louis is to bus which takes 5 h 30 min and costs . Alternatively, you can fly, which costs and takes 6 h 1 min.

Mode details

The quickest flight from Jonesboro Airport to St. Louis Airport is the direct flight which takes 1 h 30 min.

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Memphis to St. Louis bus services, operated by Megabus, arrive at St. Louis station.

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Yes, the driving distance between Memphis to St. Louis is 285 miles. It takes approximately 4 h 38 min to drive from Memphis to St. Louis.

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Air Choice One offers flights from Jonesboro Airport to St. Louis Airport.

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Map of how to get from Memphis to St. Louis.
Launch map view
  • Distance: 241.8 miles
  • Duration: 5 h 30 min

What companies run services between Memphis, TN, USA and St. Louis, MO, USA?

Megabus operates a bus from Memphis to St. Louis twice daily. Tickets cost $27 - $40 and the journey takes 5 h 30 min. Greyhound USA also services this route every 4 hours. Alternatively, Southwest Airlines, United Airlines and three other airlines fly from Memphis to St. Louis hourly.

Airlines
Delta
Website
delta.com
Flights from Memphis to St. Louis via Atlanta
Ave. Duration
4 h 33 min
When
Every day
Estimated price
$190 - $950
Flights from Memphis to St. Louis via Detroit
Ave. Duration
4 h 35 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$210 - $1,000
Flights from Memphis to St. Louis via Minneapolis
Ave. Duration
4 h 51 min
When
Every day
Estimated price
$210 - $1,000
Southwest Airlines
Website
southwest.com
Flights from Memphis to St. Louis via Chicago Midway
Ave. Duration
3 h 47 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$210 - $900
Flights from Memphis to St. Louis via Dallas
Ave. Duration
3 h 55 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$240 - $950
Flights from Little Rock to St. Louis
Ave. Duration
1 h 10 min
When
Every day
Estimated price
$190 - $900
American Airlines
Website
aa.com
Flights from Memphis to St. Louis via Dallas/Ft.Worth
Ave. Duration
4 h 27 min
When
Every day
Estimated price
$220 - $1,000
Flights from Memphis to St. Louis via Charlotte
Ave. Duration
4 h 59 min
When
Every day
Estimated price
$230 - $1,000
United Airlines
Website
united.com
Flights from Memphis to St. Louis via Chicago O'Hare
Ave. Duration
4 h 11 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$210 - $1,000
Flights from Memphis to St. Louis via Houston
Ave. Duration
4 h 45 min
When
Every day
Estimated price
$240 - $1,100
Air Choice One
Website
airchoiceone.com
Flights from Jonesboro to St. Louis
Ave. Duration
1 h 30 min
When
Every day
Estimated price
$65 - $150
Train operators
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Memphis Central Station to Carbondale Amtrak
Ave. Duration
4 h 31 min
Frequency
Once daily
Estimated price
$40 - $110
Website
amtrak.com
Coach Seat
$40 - $65
Flexi Coach Seat
$75 - $110
Business Coach Seat
$70 - $110
Room
$200 - $280
Bus operators
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Memphis, Tn to St Louis, Mo
Ave. Duration
5 h 40 min
Frequency
Every 4 hours
Estimated price
$30 - $80
Website
greyhound.com
Economy
$30 - $50
Flexible
$60 - $80
Bus from Carbondale to St Louis, Mo
Ave. Duration
2 h 5 min
Frequency
Hourly
Estimated price
$16 - $40
Website
greyhound.com
Economy
$16 - $24
Flexible
$29 - $40
Bus from Memphis, Tn to Jonesboro, Ar
Ave. Duration
1 h 30 min
Frequency
Hourly
Estimated price
$13 - $30
Website
greyhound.com
Economy
$13 - $20
Flexible
$23 - $30
Bus from Memphis, Tn to Little Rock, Ar
Ave. Duration
2 h 25 min
Frequency
Every 15 minutes
Estimated price
$19 - $45
Website
greyhound.com
Economy
$19 - $29
Flexible
$35 - $45

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More Questions & Answers

Book your Memphis to St. Louis bus tickets online with Greyhound.

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There are 193+ hotels available in St. Louis. Prices start at $70 USD per night.

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The best way to get from Memphis to Memphis Airport is to line 280 bus which takes 23 min and costs .

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