There are 6 ways to get from Memphis to St. Louis by bus, train, car or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Bus  •  5 h 50 min

  1. Take the bus from Memphis, TN to St Louis, MO via St Louis / ...

$27 - $80

5 alternative options

Train, bus  •  7 h 2 min

  1. Take the train from Memphis Central Station to Carbondale Amtrak City Of New Orleans
  2. Take the bus from Carbondale to St Louis, Mo 4700 / ...

$59 - $142

Drive  •  4 h 38 min

  1. Drive from Memphis to St. Louis 285.3 miles

$27 - $45

Fly from Memphis  •  6 h 12 min

  1. Fly from Memphis (MEM) to St. Louis (STL) MEM - STL

$195 - $955

Bus to Jonesboro, fly  •  4 h 47 min

  1. Take the bus from Memphis, Tn to Jonesboro, Ar
  2. Fly from Jonesboro (JBR) to St. Louis (STL) JBR - STL

$91 - $193

Bus to Little Rock, fly  •  6 h 52 min

  1. Take the bus from Memphis, Tn to Little Rock, Ar
  2. Fly from Little Rock (LIT) to St. Louis (STL) LIT - STL

$216 - $951

Questions & Answers

The cheapest way to get from Memphis to St. Louis is to drive which costs $27 - $45 and takes 4 h 38 min.

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The quickest way to get from Memphis to St. Louis is to drive which costs $27 - $45 and takes 4 h 38 min.

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The distance between Memphis and St. Louis is 242 miles. The road distance is 285.3 miles.

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The bus from Memphis, TN to St Louis, MO takes 5 h 50 min including transfers and departs every four hours.

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Yes, there is a direct bus departing from Memphis, TN and arriving at St Louis, MO. Services depart every four hours, and operate every day. The journey takes approximately 5 h 50 min.

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What companies run services between Memphis, TN, USA and St. Louis, MO, USA?

Megabus operates a bus from Memphis to St. Louis once daily. Tickets cost $27 - $40 and the journey takes 5 h 50 min. Greyhound USA also services this route every 4 hours. Alternatively, American Airlines, Southwest Airlines and three other airlines fly from Memphis to St. Louis hourly.

Airlines
Southwest Airlines
Website
southwest.com
Flights from Memphis to St. Louis via Houston Hobby Apt
Ave. Duration
4 h 7 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$260 - $1,000
Flights from Memphis to St. Louis via Chicago Midway
Ave. Duration
4 h 37 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$210 - $900
Flights from Memphis to St. Louis via Baltimore
Ave. Duration
5 h 5 min
When
Sunday
Estimated price
$290 - $1,100
Flights from Memphis to St. Louis via Orlando
Ave. Duration
5 h 10 min
When
Sunday
Estimated price
$300 - $1,100
Flights from Little Rock to St. Louis
Ave. Duration
1 h 6 min
When
Every day
Estimated price
$190 - $900
American Airlines
Website
aa.com
Flights from Memphis to St. Louis via Chicago O'Hare
Ave. Duration
4 h 29 min
When
Every day
Estimated price
$200 - $950
Flights from Memphis to St. Louis via Dallas/Ft.Worth
Ave. Duration
4 h 19 min
When
Every day
Estimated price
$220 - $1,000
Flights from Memphis to St. Louis via Charlotte
Ave. Duration
4 h 48 min
When
Every day
Estimated price
$230 - $1,000
Delta
Website
delta.com
Flights from Memphis to St. Louis via Atlanta
Ave. Duration
4 h 36 min
When
Every day
Estimated price
$190 - $950
Flights from Memphis to St. Louis via Detroit
Ave. Duration
4 h 41 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$210 - $1,000
Flights from Memphis to St. Louis via Minneapolis
Ave. Duration
4 h 51 min
When
Saturday
Estimated price
$210 - $1,000
United Airlines
Website
united.com
Flights from Memphis to St. Louis via Chicago O'Hare
Ave. Duration
4 h 38 min
When
Every day
Estimated price
$210 - $1,000
Air Choice One
Website
airchoiceone.com
Flights from Jonesboro to St. Louis
Ave. Duration
1 h 30 min
When
Every day
Estimated price
$65 - $150
Train operators
Amtrak
Rome2rio's guide to Amtrak
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Memphis Central Station to Carbondale Amtrak
Ave. Duration
4 h 31 min
Frequency
Once daily
Estimated price
$40 - $110
Website
amtrak.com
Coach Seat
$40 - $65
Flexi Coach Seat
$75 - $110
Business Coach Seat
$70 - $110
Room
$200 - $280
Bus operators
Greyhound USA
Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Memphis, Tn to St Louis, Mo
Ave. Duration
5 h 40 min
Frequency
Every 4 hours
Estimated price
$30 - $80
Website
greyhound.com
Economy
$30 - $50
Flexible
$60 - $80
Bus from Carbondale to St Louis, Mo
Ave. Duration
2 h 5 min
Frequency
Hourly
Estimated price
$16 - $40
Website
greyhound.com
Economy
$16 - $24
Flexible
$29 - $40
Bus from Memphis, Tn to Jonesboro, Ar
Ave. Duration
1 h 30 min
Frequency
Hourly
Estimated price
$13 - $30
Website
greyhound.com
Economy
$13 - $20
Flexible
$23 - $30
Bus from Memphis, Tn to Little Rock, Ar
Ave. Duration
2 h 25 min
Frequency
Every 20 minutes
Estimated price
$19 - $45
Website
greyhound.com
Economy
$19 - $29
Flexible
$35 - $45

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