There are 6 ways to get from Clemson to St. Louis by taxi, plane, bus (Flixbus), train (Amtrak), car, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Taxi to Greenville–Spartanburg International Airport, fly
best- Take the taxi from Clemson to Greenville–Spartanburg International Airport (GSP)taxi
- Fly from Greenville–Spartanburg International Airport (GSP) to Lambert–St. Louis International Airport (STL)plane GSP - STL
5h 23m$244–884Drive 619.4 mi
cheapest- Drive from Clemson to St. Louiscar 619.4 mi
11h 14m$113–164Bus
- Take the bus from Anderson, SC to Atlantabus Nyc
- Take the bus from Atlanta Bus Station to St Louis Bus Stationbus FlixBus N2521
14h 30m$131–277Train (Amtrak)
- Take the train from Clemson Amtrak Station to Charlottesvilletrain
- Take the train from Charlottesville to Chicago Union Stationtrain
- Take the train from Chicago Union Station to St. Louistrain
37h 7m$241–1,153Drive to Asheville Regional Airport, fly
- Drive from Clemson to Asheville-Airport-AVLcar
- Fly from Asheville Regional Airport (AVL) to Lambert–St. Louis International Airport (STL)plane AVL - STL
6h 9m$126–622Bus to Hartsfield-Jackson Atlanta International Airport, fly
- Take the bus from Anderson, SC to Atlantabus
- Fly from Hartsfield-Jackson Atlanta International Airport (ATL) to Lambert–St. Louis International Airport (STL)plane ATL - STL
6h 29m$284–600
Clemson to St. Louis by train (Amtrak)
Questions & Answers
The cheapest way to get from Clemson to St. Louis is to drive which costs $110 - $170 and takes 11h 14m.
The fastest way to get from Clemson to St. Louis is to taxi and fly which takes 5h 23m and costs $240 - $900.
No, there is no direct train from Clemson station to St. Louis. However, there are services departing from Clemson Amtrak Station and arriving at St. Louis via Charlottesville and Chicago Union Station. The journey, including transfers, takes approximately 37h 7m.
The distance between Clemson and St. Louis is 584 miles. The road distance is 623 miles.
The best way to get from Clemson to St. Louis without a car is to bus which takes 14h 30m and costs $130 - $280.
It takes approximately 5h 23m to get from Clemson to St. Louis, including transfers.
Clemson to St. Louis train services, operated by Amtrak, depart from Clemson Amtrak Station.
The best way to get from Clemson to St. Louis is to bus which takes 14h 30m and costs $130 - $280. Alternatively, you can train, which costs $240 - $1,200 and takes 37h 7m.
St. Louis is 1h behind Clemson. It is currently 10:45 PM in Clemson and 9:45 PM in St. Louis.
Clemson to St. Louis train services, operated by Amtrak, arrive at Charlottesville station.
What companies run services between Clemson, SC, USA and St. Louis, MO, USA?
You can take a vehicle from Clemson to St Louis Bus Station via Anderson, SC, Atlanta, Buford Hwy @ Mcelroy Rd, Doraville Station, Doraville Station, Garnett Station, and Atlanta Bus Station in around 14h 30m. Alternatively, you can take a train from Clemson Amtrak Station to St. Louis via Charlottesville and Chicago Union Station in around 37h 7m.
- Website
- delta.com
Flights from Greenville–Spartanburg International Airport to Lambert–St. Louis International Airport via Hartsfield-Jackson Atlanta International Airport
- Ave. Duration
- 4h 22m
- When
- Every day
- Estimated price
- $140–800
Flights from Asheville Regional Airport to Lambert–St. Louis International Airport via Hartsfield-Jackson Atlanta International Airport
- Ave. Duration
- 4h 38m
- When
- Every day
- Estimated price
- $110–600
Flights from Hartsfield-Jackson Atlanta International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 43m
- When
- Every day
- Estimated price
- $85–550
- Website
- aa.com
Flights from Greenville–Spartanburg International Airport to Lambert–St. Louis International Airport via Charlotte
- Ave. Duration
- 5h 14m
- When
- Every day
- Estimated price
- $140–800
Flights from Greenville–Spartanburg International Airport to Lambert–St. Louis International Airport via Chicago O'Hare
- Ave. Duration
- 5h 31m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $160–900
Flights from Asheville Regional Airport to Lambert–St. Louis International Airport via Chicago O'Hare
- Ave. Duration
- 4h 25m
- When
- Wednesday
- Estimated price
- $120–650
Flights from Asheville Regional Airport to Lambert–St. Louis International Airport via Charlotte
- Ave. Duration
- 5h 11m
- When
- Every day
- Estimated price
- $110–650
Flights from Asheville Regional Airport to Lambert–St. Louis International Airport via Reagan Washington
- Ave. Duration
- 8h 33m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $150–750
- Website
- southwest.com
Flights from Greenville–Spartanburg International Airport to Lambert–St. Louis International Airport via Nashville
- Ave. Duration
- 5h
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $130–750
Flights from Greenville–Spartanburg International Airport to Lambert–St. Louis International Airport via Baltimore
- Ave. Duration
- 5h
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $200–1,000
Flights from Hartsfield-Jackson Atlanta International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 47m
- When
- Every day
- Estimated price
- $85–550
Flights from Hartsfield-Jackson Atlanta International Airport to Lambert–St. Louis International Airport via Nashville
- Ave. Duration
- 4h 3m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $85–550
- Website
- united.com
Flights from Greenville–Spartanburg International Airport to Lambert–St. Louis International Airport via Chicago O'Hare
- Ave. Duration
- 5h 16m
- When
- Every day
- Estimated price
- $160–900
Flights from Asheville Regional Airport to Lambert–St. Louis International Airport via Chicago O'Hare
- Ave. Duration
- 5h 26m
- When
- Every day
- Estimated price
- $120–650
- Website
- flyfrontier.com
Flights from Hartsfield-Jackson Atlanta International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 51m
- When
- Monday, Wednesday, Friday, and Saturday
- Estimated price
- $85–550
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Clemson Amtrak Station to Charlottesville
- Ave. Duration
- 9h 13m
- Frequency
- Once daily
- Estimated price
- $75–160
- Website
- https://www.amtrak.com/home.html
Train from Charlottesville to Chicago Union Station
- Ave. Duration
- 21h 8m
- Frequency
- 3 times a week
- Estimated price
- $130–800
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to St. Louis
- Ave. Duration
- 4h 46m
- Frequency
- 5 times a day
- Estimated price
- $35–200
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 646-630-7186
- help@wandacoach.com
- Website
- wandacoach.com
Bus from Anderson, SC to Atlanta
- Ave. Duration
- 1h 30m
- Frequency
- 3 times a day
- Estimated price
- $35–55
- Website
- https://www.wandacoach.com
- Book at
- https://www.gotobus.com/wanda-travel/
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Atlanta Bus Station to St Louis Bus Station
- Ave. Duration
- 10h 40m
- Frequency
- Once daily
- Estimated price
- $60–180
- Schedules at
- flixbus.com
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
More Questions & Answers
Yes, the driving distance between Clemson to St. Louis is 623 miles. It takes approximately 11h 14m to drive from Clemson to St. Louis.
Book your Clemson to St. Louis train tickets online with Omio.
There are 353+ hotels available in St. Louis.






