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How to get fromMobile to Florida Keysby plane, bus (Greyhound), car, bus or shuttle

Find Transport to Florida Keys

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There are 8 ways to get from Mobile to Florida Keys by plane, bus (Greyhound), car, bus, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Mobile Regional Airport to Key West International Airport

    best
    1. Fly from Mobile Regional Airport (MOB) to Key West International Airport (EYW)planeMOB - EYW
    10h 42m
    $148–575

  2. Bus

    1. Take the bus from Mobile to MiamibusHouston
    2. Take the bus from Miami Airport Station to Big Pine KeybusGreyhound US0720s
    21h 50m
    $166–221

  3. Drive 843.3 mi

    1. Drive from Mobile to Florida Keyscar843.3 mi
    14h 55m
    $154–223

  4. Bus to Pensacola International Airport, fly to Key West International Airport

    1. Take the bus from Mobile Bus Station to Pensacola Airportbus
    2. Fly from Pensacola International Airport (PNS) to Key West International Airport (EYW)planePNS - EYW
    10h 39m
    $402–977

  5. Bus to Destin–Fort Walton Beach Airport, fly to Miami International Airport, shuttle

    1. Take the bus from Mobile to Crestviewbus
    2. Fly from Destin–Fort Walton Beach Airport (VPS) to Miami International Airport (MIA)planeVPS - MIA
    3. Take a shuttle bus from Miami, FL - International Airport to Big Pine Key, FLshuttle
    10h 25m
    $286–630

  6. Bus to Pensacola International Airport, fly to Miami International Airport, shuttle

    1. Take the bus from Mobile Bus Station to Pensacola Airportbus
    2. Fly from Pensacola International Airport (PNS) to Miami International Airport (MIA)planePNS - MIA
    3. Take a shuttle bus from Miami, FL - International Airport to Big Pine Key, FLshuttle
    11h 1m
    $307–722

  7. Bus to Gulfport-Biloxi Regional Airport, fly to Key West International Airport

    1. Take the bus from Mobile to Gulfportbus
    2. Fly from Gulfport-Biloxi Regional Airport (GPT) to Key West International Airport (EYW)planeGPT - EYW
    11h 9m
    $266–797

  8. Bus to Pensacola International Airport, fly to Fort Lauderdale–Hollywood International Airport, shuttle

    1. Take the bus from Mobile Bus Station to Pensacola Airportbus
    2. Fly from Pensacola International Airport (PNS) to Fort Lauderdale–Hollywood International Airport (FLL)planePNS - FLL
    3. Take a shuttle bus from Fort Lauderdale, FL - International Airport to Big Pine Key, FLshuttle
    11h 28m
    $257–502

Mobile Regional Airport (MOB) to Key West International Airport (EYW) flights

Calendar47Weekly Planes
Duration5h 46mAverage Duration
Ticket$101Cheapest Price
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Questions & Answers

What companies run services between Mobile, AL, USA and Florida Keys, FL, USA?

Delta, American Airlines, and United Airlines fly from Mobile Regional Airport (MOB) to Key West International Airport (EYW) every 4 hours. Alternatively, you can take a bus from Mobile to Florida Keys via Miami, Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 21h 50m.

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