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How to get fromMobile to Florida Keysby plane, bus (Greyhound), car, bus or shuttle

Find Transport to Florida Keys

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There are 8 ways to get from Mobile to Florida Keys by plane, bus (Greyhound), car, bus, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Mobile Regional Airport to Key West International Airport

    best
    1. Fly from Mobile Regional Airport (MOB) to Key West International Airport (EYW)plane plane MOB - EYW
    10h 56m
    $155–611

  2. Drive 843.3 mi

    cheapest
    1. Drive from Mobile to Florida Keyscar car 843.3 mi
    15h 5m
    $154–223

  3. Bus

    1. Take the bus from Mobile to Miamibus bus Houston
    2. Take the bus from Miami Airport Station to Big Pine Keybus bus Greyhound US0720s
    21h 50m
    $166–221

  4. Bus to Pensacola International Airport, fly to Key West International Airport

    1. Take the bus from Mobile Bus Station to Pensacola Airportbus bus
    2. Fly from Pensacola International Airport (PNS) to Key West International Airport (EYW)plane plane PNS - EYW
    10h 24m
    $243–972

  5. Bus to Pensacola International Airport, fly to Miami International Airport, shuttle

    1. Take the bus from Mobile Bus Station to Pensacola Airportbus bus
    2. Fly from Pensacola International Airport (PNS) to Miami International Airport (MIA)plane plane PNS - MIA
    3. Take a shuttle bus from Miami, FL - International Airport to Big Pine Key, FLshuttle bus
    10h 56m
    $308–787

  6. Bus to Gulfport-Biloxi Regional Airport, fly to Key West International Airport

    1. Take the bus from Mobile to Gulfportbus bus
    2. Fly from Gulfport-Biloxi Regional Airport (GPT) to Key West International Airport (EYW)plane plane GPT - EYW
    10h 52m
    $266–847

  7. Bus to Destin–Fort Walton Beach Airport, fly to Miami International Airport, shuttle

    1. Take the bus from Mobile to Crestviewbus bus
    2. Fly from Destin–Fort Walton Beach Airport (VPS) to Miami International Airport (MIA)plane plane VPS - MIA
    3. Take a shuttle bus from Miami, FL - International Airport to Big Pine Key, FLshuttle bus
    10h 21m
    $286–650

  8. Bus to Pensacola International Airport, fly to Fort Lauderdale–Hollywood International Airport, shuttle

    1. Take the bus from Mobile Bus Station to Pensacola Airportbus bus
    2. Fly from Pensacola International Airport (PNS) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane PNS - FLL
    3. Take a shuttle bus from Fort Lauderdale, FL - International Airport to Big Pine Key, FLshuttle bus
    11h 28m
    $258–507

Mobile Regional Airport (MOB) to Key West International Airport (EYW) flights

Calendar43Weekly Planes
Duration6h 2mAverage Duration
Ticket$107Cheapest Price
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Questions & Answers

What companies run services between Mobile, AL, USA and Florida Keys, FL, USA?

Delta, American Airlines, and United Airlines fly from Mobile Regional Airport (MOB) to Key West International Airport (EYW) every 4 hours. Alternatively, you can take a bus from Mobile to Florida Keys via Miami, Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 21h 50m.

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