There are 9 ways to get from Missouri to Florida Keys by plane, bus (Greyhound, Flixbus), train, bus, car, or shuttle
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Springfield-Branson National Airport to Key West International Airport
best- Fly from Springfield-Branson National Airport (SGF) to Key West International Airport (EYW)plane SGF - EYW
7h 45m$183–533Fly Lambert–St. Louis International Airport to Key West International Airport
cheapest- Fly from Lambert–St. Louis International Airport (STL) to Key West International Airport (EYW)plane STL - EYW
8h 58m$174–556Bus
- Take the bus from Kansas City Bus Station to St Louis Bus Stationbus
- Take the bus from St Louis Bus Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Miami Airport Stationbus
- Take the bus from Miami Airport Station to Big Pine Keybus
37h 20m$253–433Train, bus
- Take the train from Kansas City to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Miami Amtrak Stationtrain
- Take the bus from Miami Airport Station to Big Pine Keybus
2d 14h$1,383–2,231Drive 1,537.5 mi
- Drive from Kansas City to Florida Keyscar 1,537.5 mi
28h 28m$281–406Fly Kansas City to Key West International Airport
- Fly from Kansas City (MCI) to Key West International Airport (EYW)plane MCI - EYW
9h 32m$207–744Fly Lambert–St. Louis International Airport to Miami International Airport, shuttle
- Fly from Lambert–St. Louis International Airport (STL) to Miami International Airport (MIA)plane STL - MIA
- Take a shuttle bus from Miami, FL - International Airport to Big Pine Key, FL
9h 36m$654–1,086Fly Lambert–St. Louis International Airport to Fort Lauderdale–Hollywood International Airport, shuttle
- Fly from Lambert–St. Louis International Airport (STL) to Fort Lauderdale–Hollywood International Airport (FLL)plane STL - FLL
- Take a shuttle bus from Fort Lauderdale, FL - International Airport to Big Pine Key, FL
10h 16m$674–1,306Bus, shuttle
- Take the bus from Kansas City to Texarkanabus
- Take the bus from Texarkana to Houston Bus Stationbus
- Take the bus from Houston - Harrisburg Blvd to Miamibus
- Take a shuttle bus from Miami, FL - International Airport to Summerland Key - Mote Marine Lab
2d$522–691
Missouri to Florida Keys by bus and foot
Comparing Your Travel Options
The cheapest way to get from Missouri to Florida Keys is to bus which costs $250 - $440 and takes 37h 20m.
The fastest way to get from Missouri to Florida Keys is to fly which takes 7h 45m and costs $180 - $550.
No, there is no direct bus from Missouri station to Florida Keys. However, there are services departing from Kansas City Bus Station and arriving at Sugarloaf Key - Lower - Sugarloaf Lodge via St Louis Bus Station, Atlanta Bus Station, Miami Airport Station and Big Pine Key - CVS / MM30. The journey, including transfers, takes approximately 37h 20m.
The distance between Missouri and Florida Keys is 1149 miles. The road distance is 1546.5 miles.
The best way to get from Missouri to Florida Keys without a car is to bus which takes 37h 20m and costs $250 - $440.
It takes approximately 7h 45m to get from Missouri to Florida Keys, including transfers.
Missouri to Florida Keys bus services, operated by Greyhound USA, depart from Kansas City Bus Station.
The best way to get from Missouri to Florida Keys is to fly which takes 7h 45m and costs $180 - $550. Alternatively, you can bus, which costs $250 - $440 and takes 37h 20m.
Missouri to Florida Keys bus services, operated by Greyhound USA, arrive at St Louis Bus Station.
Yes, the driving distance between Missouri to Florida Keys is 1546 miles. It takes approximately 28h 28m to drive from Missouri to Florida Keys.
What companies run services between Missouri, USA and Florida Keys, FL, USA?
Delta, American Airlines, and United Airlines fly from Springfield-Branson National Airport (SGF) to Key West International Airport (EYW) 4 times a day. Alternatively, you can take a bus from Kansas City Bus Station to Florida Keys via St Louis Bus Station, Atlanta Bus Station, Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 37h 20m.
- Website
- southwest.com
Flights from Lambert–St. Louis International Airport to Miami International Airport
- Ave. Duration
- 2h 40m
- When
- Every day
- Estimated price
- $100–500
Flights from Lambert–St. Louis International Airport to Miami International Airport via Nashville
- Ave. Duration
- 5h 16m
- When
- Monday, Thursday, Friday, Sunday, and Saturday
- Estimated price
- $100–550
Flights from Lambert–St. Louis International Airport to Miami International Airport via Orlando
- Ave. Duration
- 5h 18m
- When
- Sunday, Monday, Thursday, Friday, Tuesday, and Wednesday
- Estimated price
- $100–550
Flights from Lambert–St. Louis International Airport to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 2h 48m
- When
- Every day
- Estimated price
- $110–600
Flights from Lambert–St. Louis International Airport to Fort Lauderdale–Hollywood International Airport via Tampa
- Ave. Duration
- 4h 52m
- When
- Sunday and Saturday
- Estimated price
- $110–600
Flights from Lambert–St. Louis International Airport to Fort Lauderdale–Hollywood International Airport via Orlando
- Ave. Duration
- 4h 25m
- When
- Sunday
- Estimated price
- $110–600
Flights from Lambert–St. Louis International Airport to Fort Lauderdale–Hollywood International Airport via Nashville
- Ave. Duration
- 5h 3m
- When
- Monday, Thursday, Friday, Tuesday, Wednesday, and Sunday
- Estimated price
- $110–600
- Website
- delta.com
Flights from Springfield-Branson National Airport to Key West International Airport via Atlanta
- Ave. Duration
- 5h 16m
- When
- Every day
- Estimated price
- $90–420
Flights from Lambert–St. Louis International Airport to Key West International Airport via Atlanta
- Ave. Duration
- 5h 10m
- When
- Every day
- Estimated price
- $95–460
Flights from Kansas City to Key West International Airport via Atlanta
- Ave. Duration
- 5h 27m
- When
- Every day
- Estimated price
- $130–650
Flights from Lambert–St. Louis International Airport to Fort Lauderdale–Hollywood International Airport via Atlanta
- Ave. Duration
- 4h 48m
- When
- Every day
- Estimated price
- $110–600
- Website
- aa.com
Flights from Springfield-Branson National Airport to Key West International Airport via Miami International Airport
- Ave. Duration
- 5h 3m
- When
- Saturday
- Estimated price
- $90–420
Flights from Springfield-Branson National Airport to Key West International Airport via Dallas/Ft.Worth
- Ave. Duration
- 5h 16m
- When
- Every day
- Estimated price
- $100–460
Flights from Springfield-Branson National Airport to Key West International Airport via Charlotte
- Ave. Duration
- 6h 14m
- When
- Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $100–460
Flights from Lambert–St. Louis International Airport to Key West International Airport via Dallas/Ft.Worth
- Ave. Duration
- 5h 42m
- When
- Every day
- Estimated price
- $120–550
Flights from Lambert–St. Louis International Airport to Key West International Airport via Charlotte
- Ave. Duration
- 5h 57m
- When
- Every day
- Estimated price
- $100–500
Flights from Lambert–St. Louis International Airport to Key West International Airport via Miami International Airport
- Ave. Duration
- 6h 57m
- When
- Tuesday
- Estimated price
- $100–480
Flights from Kansas City to Key West International Airport via Dallas/Ft.Worth
- Ave. Duration
- 6h 6m
- When
- Every day
- Estimated price
- $140–650
Flights from Kansas City to Key West International Airport via Miami International Airport
- Ave. Duration
- 6h 56m
- When
- Tuesday
- Estimated price
- $130–650
Flights from Kansas City to Key West International Airport via Charlotte
- Ave. Duration
- 7h 14m
- When
- Tuesday
- Estimated price
- $140–650
Flights from Lambert–St. Louis International Airport to Miami International Airport
- Ave. Duration
- 2h 47m
- When
- Every day
- Estimated price
- $100–500
- Website
- united.com
Flights from Springfield-Branson National Airport to Key West International Airport via Chicago O'Hare
- Ave. Duration
- 7h 1m
- When
- Saturday
- Estimated price
- $110–500
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Kansas City to Chicago Union Station
- Ave. Duration
- 7h 41m
- Frequency
- Twice daily
- Estimated price
- $240–370
- Website
- Amtrak
Train from Chicago Union Station to Miami Amtrak Station
- Ave. Duration
- 46h 29m
- Frequency
- Once daily
- Estimated price
- $1,100–1,800
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- Greyhound
Bus from Kansas City Bus Station to St Louis Bus Station
- Ave. Duration
- 4h
- Frequency
- 4 times a day
- Estimated price
- $40–65
- Website
- Greyhound
Bus from St Louis Bus Station to Atlanta Bus Station
- Ave. Duration
- 11h 40m
- Frequency
- Once daily
- Estimated price
- $95–150
- Website
- Greyhound
Bus from Atlanta Bus Station to Miami Airport Station
- Ave. Duration
- 17h 20m
- Frequency
- Once daily
- Estimated price
- $120–180
- Website
- Greyhound
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 40m
- Frequency
- 3 times a day
- Estimated price
- $22–35
- Website
- Greyhound
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 40m
- Frequency
- 3 times a day
- Estimated price
- $22–35
- Website
- Greyhound
Bus from Texarkana to Houston Bus Station
- Ave. Duration
- 8h
- Frequency
- Once daily
- Estimated price
- $60–90
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from St Louis Bus Station to Atlanta Bus Station
- Ave. Duration
- 10h
- Frequency
- 5 times a week
- Estimated price
- $85–130
- Schedules at
- Flixbus USA
Bus from Atlanta Bus Station to Miami Airport Station
- Ave. Duration
- 13h 30m
- Frequency
- Once daily
- Estimated price
- $100–160
- Schedules at
- Flixbus USA
- Phone
- +1 (305) 289-9997
- groups@keysshuttle.com
- Website
- Keys Shuttle
Shuttle from Miami, FL - International Airport to Big Pine Key, FL
- Ave. Duration
- 3h
- Frequency
- 3 times a day
- Estimated price
- $150–180
- Website
- Keys Shuttle
Shuttle from Fort Lauderdale, FL - International Airport to Big Pine Key, FL
- Ave. Duration
- 3h 30m
- Frequency
- 3 times a day
- Estimated price
- $170–200
- Website
- Keys Shuttle
Shuttle from Miami, FL - International Airport to Summerland Key - Mote Marine Lab
- Ave. Duration
- 3h 30m
- Frequency
- 3 times a day
- Estimated price
- $150–180
- Website
- Keys Shuttle
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Kansas City to Texarkana
- Ave. Duration
- 8h 55m
- Frequency
- Twice daily
- Estimated price
- $110–160
- Book at
- Jefferson Lines
- Adult
- $110–160
- Phone
- +1 800-923-1799
- contactus@omexusa.net
- Website
- Omnibus Express
Bus from Houston - Harrisburg Blvd to Miami
- Ave. Duration
- 24h 14m
- Frequency
- Once daily
- Estimated price
- $180–240
- Schedules at
- Omnibus Express
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