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How to get fromMobile to St. Louisby bus, plane, bus (Flixbus), train, car, taxi or bus (Greyhound, Flixbus)

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There are 9 ways to get from Mobile to St. Louis by bus, plane, bus (Flixbus), train, car, taxi, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Pensacola International Airport, fly to Lambert–St. Louis International Airport

    best
    1. Take the bus from Mobile Bus Station to Pensacola Airportbus bus
    2. Fly from Pensacola International Airport (PNS) to Lambert–St. Louis International Airport (STL)plane plane PNS - STL
    6h 15m
    $139–756

  2. Bus

    cheapest
    1. Take the bus from Mobile Bus Station to New Orleans Bus Stationbus bus Greyhound US0602
    2. Take the bus from New Orleans Bus Station to St Louis Bus Stationbus bus Greyhound US1173
    19h 57m
    $88–162

  3. Bus via Sandy Springs

    1. Take the bus from Mobile to Atlantabus bus Houston
    2. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus FlixBus N2521
    18h 54m
    $172–327

  4. Bus, train

    1. Take the bus from Mobile Bus Station to New Orleans Bus Stationbus bus
    2. Take the train from New Orleans Union Passenger Terminal to Carbondaletrain train
    3. Take the bus from Carbondale to St. Louisbus bus
    21h 42m
    $131–267

  5. Drive 642.5 mi

    1. Drive from Mobile to St. Louiscar car 642.5 mi
    11h 56m
    $118–170

  6. Fly Mobile Regional Airport to Lambert–St. Louis International Airport

    1. Fly from Mobile Regional Airport (MOB) to Lambert–St. Louis International Airport (STL)plane plane MOB - STL
    8h 55m
    $125–646

  7. Bus to Destin–Fort Walton Beach Airport, fly to Midamerica St. Louis Airport

    1. Take the bus from Mobile to Crestviewbus bus
    2. Fly from Destin–Fort Walton Beach Airport (VPS) to Midamerica St. Louis Airport (BLV)plane plane VPS - BLV
    6h 7m
    $185–518

  8. Bus to Gulfport-Biloxi Regional Airport, fly to Lambert–St. Louis International Airport

    1. Take the bus from Mobile to Gulfportbus bus
    2. Fly from Gulfport-Biloxi Regional Airport (GPT) to Lambert–St. Louis International Airport (STL)plane plane GPT - STL
    8h 50m
    $242–881

  9. Bus, taxi to Northwest Florida Beaches International Airport, fly to Lambert–St. Louis International Airport

    1. Take the bus from Love's Travel Stop - Loxley to Whataburger - Defuniak Springsbus bus
    2. Take the taxi from Whataburger - Defuniak Springs to Northwest Florida Beaches International Airport (ECP)taxi taxi
    3. Fly from Northwest Florida Beaches International Airport (ECP) to Lambert–St. Louis International Airport (STL)plane plane ECP - STL
    7h 32m
    $299–943

Mobile to St. Louis by bus and train

Calendar7Weekly Services
Duration21h 42mAverage Duration
Ticket$131Cheapest Price
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Questions & Answers

What companies run services between Mobile, AL, USA and St. Louis, MO, USA?

You can take a bus from Mobile to St Louis Bus Station via Mobile, Atlanta, Doraville Station, Garnett Station, and Atlanta Bus Station in around 18h 54m. Alternatively, Delta, United Airlines, and American Airlines fly from Mobile Regional Airport (MOB) to Lambert–St. Louis International Airport (STL) every 2 hours.

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