There are 8 ways to get from Sebastian to Florida Keys by bus (Greyhound), car, shuttle, plane, bus, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus via Fort Pierce South
best- Take the bus from Sebastian to Fort Pierce
- Take the bus from Fort Pierce to Miami Airport
- Take the bus from Miami Airport Station to Big Pine Key
10h 21m$75–167Drive 294.5 mi
cheapest- Drive from Sebastian to Florida Keys294.5 mi
5h 46m$54–78Shuttle to Orlando, fly
- Take a shuttle bus from Sebastian, FL - BP to Orlando Airport
- Fly from Orlando (MCO) to Key West International Airport (EYW)MCO - EYW
6h 39m$222–712Bus, train
- Take the bus from Sebastian to Fort Pierce
- Take the bus from Fort Pierce to West Palm Beach, FL
- Take the train from West Palm Beach Station to Miami Airport Station
- Take the bus from Miami Airport Station to Big Pine Key
11h 12m$74–168Bus, shuttle
- Take the bus from Sebastian to Miami Airport StationGreyhound US0710s
- Take a shuttle bus from Miami, FL - International Airport to Summerland Key - Mote Marine LabTo the Keys
11h 14m$175–242Bus (Greyhound)
- Take the bus from Sebastian to Miami Airport StationGreyhound US0710s
- Take the bus from Miami Airport Station to Big Pine KeyGreyhound US0720s
11h 31m$66–92Bus, bus to Miami International Airport, fly
- Take the bus from Sebastian to Fort Pierce
- Take the bus from Fort Pierce to Miami Airport
- Fly from Miami International Airport (MIA) to Key West International Airport (EYW)MIA - EYW
9h 2m$249–692Bus, bus to Fort Lauderdale–Hollywood International Airport, fly
- Take the bus from Sebastian to Fort Pierce
- Take the bus from Fort Pierce to Fort Lauderdale Airport
- Fly from Fort Lauderdale–Hollywood International Airport (FLL) to Key West International Airport (EYW)FLL - EYW
8h 12m$152–567
Orlando (MCO) to Key West International Airport (EYW) flights
Questions & Answers
The cheapest way to get from Sebastian to Florida Keys is to drive which costs $50 - $80 and takes 5h 46m.
The fastest way to get from Sebastian to Florida Keys is to drive which takes 5h 46m and costs $50 - $80.
The distance between Sebastian and Florida Keys is 308 miles. The road distance is 296.2 miles.
The best way to get from Sebastian to Florida Keys without a car is to bus via Fort Pierce South which takes 10h 21m and costs $75 - $170.
It takes approximately 10h 21m to get from Sebastian to Florida Keys, including transfers.
Yes, the driving distance between Sebastian to Florida Keys is 296 miles. It takes approximately 5h 46m to drive from Sebastian to Florida Keys.
There are 117+ hotels available in Florida Keys.
What companies run services between Sebastian, FL, USA and Florida Keys, FL, USA?
You can take a vehicle from Sebastian to Florida Keys via Sebastian, Fort Pierce, Miami Airport, Miami International Airport, Miami, Airport Intermodal Station, Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 10h 21m.
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- Website
- aa.com
Flights from Miami International Airport to Key West International Airport
- Ave. Duration
- 1h 6m
- When
- Every day
- Estimated price
- $30–250
- Website
- flybreeze.com
Flights from Orlando to Key West International Airport
- Ave. Duration
- 1h 15m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $110–600
- Website
- spirit.com
Flights from Fort Lauderdale–Hollywood International Airport to Key West International Airport
- Ave. Duration
- 50 min
- When
- Thursday, Saturday, and Sunday
- Estimated price
- $55–220
- Phone
- +1 800-874-7245
- Website
- tri-rail.com
Train from West Palm Beach Station to Miami Airport Station
- Ave. Duration
- 1h 49m
- Frequency
- Hourly
- Estimated price
- $5–11
- Website
- https://www.tri-rail.com
- Weekend | Holiday
- $5
- Weekday
- $8–11
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Sebastian to Fort Pierce
- Ave. Duration
- 40 min
- Frequency
- Once daily
- Estimated price
- $22–50
- Website
- https://www.greyhound.com/
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 35m
- Frequency
- Twice daily
- Estimated price
- $21–30
- Website
- https://www.greyhound.com/
Bus from Fort Pierce to West Palm Beach, FL
- Ave. Duration
- 1h 5m
- Frequency
- Twice daily
- Estimated price
- $15–22
- Website
- https://www.greyhound.com/
Bus from Sebastian to Miami Airport Station
- Ave. Duration
- 5h 15m
- Frequency
- Once daily
- Estimated price
- $28–40
- Website
- https://www.greyhound.com/
- Phone
- +1 877 733 0724
- Website
- redcoachusa.com
Bus from Fort Pierce to Miami Airport
- Ave. Duration
- 2h 20m
- Frequency
- 3 times a day
- Estimated price
- $15–65
- Website
- https://www.redcoachusa.com
- Web
- $15–65
Bus from Fort Pierce to West Palm Beach, FL
- Ave. Duration
- 55 min
- Frequency
- 3 times a day
- Estimated price
- $9–55
- Website
- https://www.redcoachusa.com
- Web
- $9–55
Bus from Fort Pierce to Fort Lauderdale Airport
- Ave. Duration
- 1h 40m
- Frequency
- Once daily
- Estimated price
- $13–60
- Website
- https://www.redcoachusa.com
- Web
- $13–60
- Phone
- +1 772-343-0217
- Website
- smartshuttleline.com
Shuttle from Sebastian, FL - BP to Orlando Airport
- Ave. Duration
- 1h 22m
- Frequency
- 4 times a day
- Estimated price
- $60–75
- Schedules at
- smartshuttleline.com
- one passenger
- $60–75
- Phone
- +1 (305) 289-9997
- groups@keysshuttle.com
- Website
- keysshuttle.com
Shuttle from Miami, FL - International Airport to Summerland Key - Mote Marine Lab
- Ave. Duration
- 3h 30m
- Frequency
- 4 times a day
- Estimated price
- $130–180
- Website
- https://www.keysshuttle.com
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