Rome2Rio

How to get fromSebastian to Florida Keysby bus (Greyhound), car, shuttle, plane, bus or train

Find Transport to Florida Keys

See all options

There are 8 ways to get from Sebastian to Florida Keys by bus (Greyhound), car, shuttle, plane, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus via Fort Pierce South

    best
    1. Take the bus from Sebastian to Fort Piercebus
    2. Take the bus from Fort Pierce to Miami Airportbus
    3. Take the bus from Miami Airport Station to Big Pine Keybus
    10h 21m
    $75–167
  2. Drive 294.5 mi

    cheapest
    1. Drive from Sebastian to Florida Keyscar294.5 mi
    5h 46m
    $54–78
  3. Shuttle to Orlando, fly

    1. Take a shuttle bus from Sebastian, FL - BP to Orlando Airportshuttle
    2. Fly from Orlando (MCO) to Key West International Airport (EYW)planeMCO - EYW
    6h 39m
    $222–712
  4. Bus, train

    1. Take the bus from Sebastian to Fort Piercebus
    2. Take the bus from Fort Pierce to West Palm Beach, FLbus
    3. Take the train from West Palm Beach Station to Miami Airport Stationtrain
    4. Take the bus from Miami Airport Station to Big Pine Keybus
    11h 12m
    $74–168
  5. Bus, shuttle

    1. Take the bus from Sebastian to Miami Airport StationbusGreyhound US0710s
    2. Take a shuttle bus from Miami, FL - International Airport to Summerland Key - Mote Marine LabshuttleTo the Keys
    11h 14m
    $175–242
  6. Bus (Greyhound)

    1. Take the bus from Sebastian to Miami Airport StationbusGreyhound US0710s
    2. Take the bus from Miami Airport Station to Big Pine KeybusGreyhound US0720s
    11h 31m
    $66–92
  7. Bus, bus to Miami International Airport, fly

    1. Take the bus from Sebastian to Fort Piercebus
    2. Take the bus from Fort Pierce to Miami Airportbus
    3. Fly from Miami International Airport (MIA) to Key West International Airport (EYW)planeMIA - EYW
    9h 2m
    $249–692
  8. Bus, bus to Fort Lauderdale–Hollywood International Airport, fly

    1. Take the bus from Sebastian to Fort Piercebus
    2. Take the bus from Fort Pierce to Fort Lauderdale Airportbus
    3. Fly from Fort Lauderdale–Hollywood International Airport (FLL) to Key West International Airport (EYW)planeFLL - EYW
    8h 12m
    $152–567

Orlando (MCO) to Key West International Airport (EYW) flights

Calendar4Weekly Planes
Duration1h 15mAverage Duration
Ticket$112Cheapest Price
See schedules

Questions & Answers

What companies run services between Sebastian, FL, USA and Florida Keys, FL, USA?

You can take a vehicle from Sebastian to Florida Keys via Sebastian, Fort Pierce, Miami Airport, Miami International Airport, Miami, Airport Intermodal Station, Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 10h 21m.

Transport is disrupted due to the Russia-Ukraine war. Read more

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound