There are 8 ways to get from Milwaukee to Lexington by bus, plane, car, bus (Flixbus, Greyhound), train, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus to Chicago O'Hare International Airport, fly to Louisville International Airport, drive
best- Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus
- Fly from Chicago O'Hare International Airport (ORD) to Louisville International Airport (SDF)plane ORD - SDF
- Drive from Louisville-Airport-SDF to Lexingtoncar
5h 49m$249–609Bus to Chicago O'Hare International Airport, fly to Blue Grass Airport
cheapest- Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus
- Fly from Chicago O'Hare International Airport (ORD) to Blue Grass Airport (LEX)plane ORD - LEX
6h 39m$77–320Bus
- Take the bus from Milwaukee Intermodal Station to Chicago Bus Stationbus FlixBus 2548 / ...
- Take the bus from Chicago Bus Station to Lexington Bus Stopbus Greyhound US0120
12h 22m$97–207Train, bus
- Take the train from Milwaukee to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Indianapolistrain
- Take the bus from Indianapolis Union Station to Lexington Bus Stopbus
12h 25m$119–210Drive 450.7 mi
- Drive from Milwaukee to Lexingtoncar 450.7 mi
8h 11m$83–119Fly General Mitchell International Airport to Blue Grass Airport
- Fly from General Mitchell International Airport (MKE) to Blue Grass Airport (LEX)plane MKE - LEX
7h 22m$84–632Train to Chicago Midway International Airport, fly to Louisville International Airport, drive
- Take the train from Milwaukee to Chicago Union Stationtrain
- Fly from Chicago Midway International Airport (MDW) to Louisville International Airport (SDF)plane MDW - SDF
- Drive from Louisville-Airport-SDF to Lexingtoncar
6h 13m$113–614Bus via Chicago O'Hare Airport (ORD)
- Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus Wisconsin Coach Lines
- Take the bus from Chicago to Lexington Bus Stopbus Greyhound US0120
13h 39m$103–166
Chicago O'Hare International Airport (ORD) to Louisville International Airport (SDF) flights
Questions & Answers
The cheapest way to get from Milwaukee to Lexington is to drive which costs $80 - $120 and takes 8h 11m.
The fastest way to get from Milwaukee to Lexington is to bus and fly and drive which takes 5h 49m and costs $240 - $650.
The distance between Milwaukee and Lexington is 451 miles. The road distance is 453.3 miles.
The best way to get from Milwaukee to Lexington without a car is to bus which takes 12h 22m and costs $95 - $210.
It takes approximately 5h 49m to get from Milwaukee to Lexington, including transfers.
The best way to get from Milwaukee to Lexington is to bus which takes 12h 22m and costs $95 - $210. Alternatively, you can fly, which costs $80 - $650 and takes 7h 22m.
Lexington is 1h ahead of Milwaukee. It is currently 2:36 AM in Milwaukee and 3:36 AM in Lexington.
Yes, the driving distance between Milwaukee to Lexington is 453 miles. It takes approximately 8h 11m to drive from Milwaukee to Lexington.
There are 118+ hotels available in Lexington.
What companies run services between Milwaukee, WI, USA and Lexington, KY, USA?
You can take a bus from Milwaukee Intermodal Station to Lexington via Chicago Bus Station and Lexington Bus Stop in around 12h 22m. Alternatively, Delta, United Airlines, and American Airlines fly from General Mitchell International Airport (MKE) to Blue Grass Airport (LEX) every 3 hours.
- Website
- united.com
Flights from Chicago O'Hare International Airport to Louisville International Airport
- Ave. Duration
- 1h 38m
- When
- Every day
- Estimated price
- $55–380
Flights from General Mitchell International Airport to Blue Grass Airport via Chicago O'Hare International Airport
- Ave. Duration
- 4h 7m
- When
- Every day
- Estimated price
- $80–550
Flights from Chicago O'Hare International Airport to Blue Grass Airport
- Ave. Duration
- 1h 34m
- When
- Every day
- Estimated price
- $40–280
- Website
- aa.com
Flights from Chicago O'Hare International Airport to Louisville International Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- $55–380
Flights from General Mitchell International Airport to Blue Grass Airport via Charlotte
- Ave. Duration
- 5h 40m
- When
- Every day
- Estimated price
- $130–700
Flights from General Mitchell International Airport to Blue Grass Airport via Chicago O'Hare International Airport
- Ave. Duration
- 5h 25m
- When
- Saturday
- Estimated price
- $80–550
Flights from General Mitchell International Airport to Blue Grass Airport via Philadelphia
- Ave. Duration
- 6h 30m
- When
- Every day
- Estimated price
- $150–750
Flights from Chicago O'Hare International Airport to Blue Grass Airport
- Ave. Duration
- 1h 28m
- When
- Every day
- Estimated price
- $40–280
- Website
- delta.com
Flights from General Mitchell International Airport to Blue Grass Airport via Detroit
- Ave. Duration
- 4h 58m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $95–600
Flights from General Mitchell International Airport to Blue Grass Airport via Atlanta
- Ave. Duration
- 5h 1m
- When
- Every day
- Estimated price
- $130–700
- Website
- southwest.com
Flights from Chicago Midway International Airport to Louisville International Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- $75–550
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Milwaukee to Chicago Union Station
- Ave. Duration
- 1h 29m
- Frequency
- Every 4 hours
- Estimated price
- $22–40
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to Indianapolis
- Ave. Duration
- 4h 54m
- Frequency
- 3 times a week
- Estimated price
- $30–65
- Website
- https://www.amtrak.com/home.html
- Phone
- (866) 912 6224
- questions@coachusa.com
- Website
- coachusa.com
Bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departures
- Ave. Duration
- 1h 50m
- Frequency
- Every 2 hours
- Estimated price
- $35–38
- Schedules at
- coachusa.com
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Milwaukee Intermodal Station to Chicago Bus Station
- Ave. Duration
- 2h 15m
- Frequency
- 3 times a day
- Estimated price
- $19–35
- Schedules at
- flixbus.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Milwaukee Intermodal Station to Chicago Bus Station
- Ave. Duration
- 1h 45m
- Frequency
- 3 times a day
- Estimated price
- $19–55
- Website
- https://www.greyhound.com/
Bus from Chicago Bus Station to Lexington Bus Stop
- Ave. Duration
- 8h 55m
- Frequency
- Once daily
- Estimated price
- $50–120
- Website
- https://www.greyhound.com/
Bus from Indianapolis Union Station to Lexington Bus Stop
- Ave. Duration
- 3h 50m
- Frequency
- Once daily
- Estimated price
- $40–75
- Website
- https://www.greyhound.com/
Bus from Chicago to Lexington Bus Stop
- Ave. Duration
- 8h 30m
- Frequency
- Once daily
- Estimated price
- $50–100
- Website
- https://www.greyhound.com/
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