There are 5 ways to get from Key West to Murrells Inlet by plane, bus, train, car, bus (Greyhound, Flixbus), or shuttle
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Key West International Airport (EYW) to Myrtle Beach (MYR)EYW - MYR
4h 51m$127–464Bus, train, drive
cheapest- Take the bus from N Roosevelt & 4th Street to Big Pine Key - Auto Store / NAPA MM30Lks
- Take the bus from Big Pine Key to Miami Airport Station
- Take the train from Hollywood Amtrak Station to Kingstree Station
- Drive from Kingstree Station to Murrells Inlet
23h 2m$106–282Bus
- Take the bus from N Roosevelt & 3rd Street to Big Pine Key - Auto Store / NAPA MM30Lks
- Take the bus from Big Pine Key to Miami Airport Station
- Take the bus from Miami Airport Station to Jacksonville
- Take the bus from Jacksonville to Florence Bus Station
- Take the bus from Florence to Myrtle Beach, SC
24h 42m$167–374Drive 820.5 mi
- Drive from Key West to Murrells Inlet820.5 mi
14h 52m$150–217Shuttle, train, bus
- Take a shuttle bus from Key West, FL to Miami, FL - International Airport
- Take the train from Miami Amtrak Station to Charleston Amtrak Station
- Take the bus from Charleston Bus Station to Myrtle Beach Bus Station
24h 7m$294–529
Key West International Airport (EYW) to Myrtle Beach (MYR) flights
Questions & Answers
The cheapest way to get from Key West to Murrells Inlet is to drive which costs $150 - $220 and takes 14h 52m.
The fastest way to get from Key West to Murrells Inlet is to fly which takes 4h 51m and costs $120 - $470.
The distance between Key West and Murrells Inlet is 672 miles. The road distance is 825.3 miles.
The best way to get from Key West to Murrells Inlet without a car is to bus which takes 24h 42m and costs $160 - $380.
It takes approximately 4h 51m to get from Key West to Murrells Inlet, including transfers.
The best way to get from Key West to Murrells Inlet is to fly which takes 4h 51m and costs $120 - $470. Alternatively, you can bus, which costs $160 - $380 and takes 24h 42m.
Yes, the driving distance between Key West to Murrells Inlet is 825 miles. It takes approximately 14h 52m to drive from Key West to Murrells Inlet.
There are 2885+ hotels available in Murrells Inlet.
What companies run services between Key West, FL, USA and Murrells Inlet, SC, USA?
American Airlines, Delta, and Spirit Airlines fly from Key West International Airport (EYW) to Myrtle Beach (MYR) every 4 hours. Alternatively, you can take a bus from N Roosevelt & 3rd Street to Murrells Inlet via Big Pine Key - Auto Store / NAPA MM30, Big Pine Key, Miami Airport Station, Jacksonville, Florence Bus Station, Florence, and Myrtle Beach, SC in around 24h 42m.
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- Website
- aa.com
Flights from Key West International Airport to Myrtle Beach via Charlotte
- Ave. Duration
- 5h 7m
- When
- Every day
- Estimated price
- $80–410
- Website
- delta.com
Flights from Key West International Airport to Myrtle Beach via Atlanta
- Ave. Duration
- 5h 43m
- When
- Every day
- Estimated price
- $85–430
- Website
- spirit.com
Flights from Key West International Airport to Myrtle Beach via Fort Lauderdale
- Ave. Duration
- 5h 28m
- When
- Thursday, Saturday, and Sunday
- Estimated price
- $75–400
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Hollywood Amtrak Station to Kingstree Station
- Ave. Duration
- 13h 51m
- Frequency
- Once daily
- Estimated price
- $65–220
- Website
- https://www.amtrak.com/home.html
- Coach Seat - Advance Purchase
- $65–180
- Coach Seat short notice purchase
- $90–220
- Business - advance purchase
- $120–500
- Business Class
- $200–500
Train from Miami Amtrak Station to Charleston Amtrak Station
- Ave. Duration
- 13h 15m
- Frequency
- Once daily
- Estimated price
- $85–240
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 305-809-3700
- Website
- cityofkeywest-fl.gov
Bus from N Roosevelt & 4th Street to Big Pine Key - Auto Store / NAPA MM30
- Ave. Duration
- 53 min
- Frequency
- Every 3 hours
- Estimated price
- $2–4
- Schedules at
- https://www.cityofkeywest-fl.gov/595/Schedules-and-Route-Maps
Bus from N Roosevelt & 3rd Street to Big Pine Key - Auto Store / NAPA MM30
- Ave. Duration
- 54 min
- Frequency
- Every 3 hours
- Estimated price
- $2–4
- Schedules at
- https://www.cityofkeywest-fl.gov/595/Schedules-and-Route-Maps
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Big Pine Key to Miami Airport Station
- Ave. Duration
- 3h 35m
- Frequency
- Twice daily
- Estimated price
- $25–35
- Website
- https://www.greyhound.com/
Bus from Miami Airport Station to Jacksonville
- Ave. Duration
- 9h 45m
- Frequency
- Once daily
- Estimated price
- $45–85
- Website
- https://www.greyhound.com/
Bus from Florence to Myrtle Beach, SC
- Ave. Duration
- 1h 40m
- Frequency
- Once daily
- Estimated price
- $15–19
- Website
- https://www.greyhound.com/
Bus from Charleston Bus Station to Myrtle Beach Bus Station
- Ave. Duration
- 2h 25m
- Frequency
- Once daily
- Estimated price
- $11–15
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Miami Airport Station to Jacksonville
- Ave. Duration
- 9h 10m
- Frequency
- Twice daily
- Estimated price
- $45–90
- Schedules at
- flixbus.com
Bus from Jacksonville to Florence Bus Station
- Ave. Duration
- 5h 10m
- Frequency
- Once daily
- Estimated price
- $35–95
- Schedules at
- flixbus.com
- Adult
- $35–95
- Phone
- +1 404-591-2750
- info@southeasternstages.com
- Website
- southeasternstages.com
Bus from Florence to Myrtle Beach, SC
- Ave. Duration
- 1h 25m
- Frequency
- Once daily
- Estimated price
- $25–95
- Schedules at
- southeasternstages.com
- Phone
- +1 (305) 289-9997
- groups@keysshuttle.com
- Website
- keysshuttle.com
Shuttle from Key West, FL to Miami, FL - International Airport
- Ave. Duration
- 4h
- Frequency
- 4 times a day
- Estimated price
- $150–210
- Website
- https://www.keysshuttle.com
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