There are 5 ways to get from Key West to Murrells Inlet by plane, bus, train, car, or shuttle
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Myrtle Beach
best- Fly from Key West International Airport (EYW) to Myrtle Beach (MYR)plane EYW - MYR
5h 7m$142–554Bus, train, drive
- Take the bus from N Roosevelt & 4th Street to Big Pine Key - Auto Store / NAPA MM30bus Lks
- Take the bus from Big Pine Key to Miami Airport Stationbus
- Take the train from Hollywood Amtrak Station to Kingstree Stationtrain
- Drive from Kingstree Station to Murrells Inletcar
22h 58m$228–512Drive 820.5 mi
- Drive from Key West to Murrells Inletcar 820.5 mi
15h 1m$150–217Fly to Wilmington International Airport, bus
- Fly from Key West International Airport (EYW) to Wilmington International Airport (ILM)plane EYW - ILM
- Take the bus from Wilmington Cape Fear Public Transit to Myrtle Beach Bus Stationbus
7h 33m$199–812Shuttle, train, bus
- Take a shuttle bus from Key West, FL to Miami, FL - International Airport
- Take the train from Miami Amtrak Station to Charleston Amtrak Stationtrain
- Take the bus from Charleston Bus Station to Myrtle Beach Bus Stationbus
24h 7m$410–709
Key West International Airport (EYW) to Myrtle Beach (MYR) flights
Questions & Answers
The cheapest way to get from Key West to Murrells Inlet is to drive which costs $150 - $220 and takes 15h 1m.
The fastest way to get from Key West to Murrells Inlet is to fly which takes 5h 7m and costs $140 - $600.
The distance between Key West and Murrells Inlet is 672 miles. The road distance is 825.3 miles.
The best way to get from Key West to Murrells Inlet without a car is to shuttle and train and bus which takes 24h 7m and costs $410 - $750.
It takes approximately 5h 7m to get from Key West to Murrells Inlet, including transfers.
Yes, the driving distance between Key West to Murrells Inlet is 825 miles. It takes approximately 15h 1m to drive from Key West to Murrells Inlet.
There are 8961+ hotels available in Murrells Inlet.
What companies run services between Key West, FL, USA and Murrells Inlet, SC, USA?
Delta and American Airlines fly from Key West International Airport (EYW) to Myrtle Beach (MYR) 5 times a day.
- Website
- aa.com
Flights from Key West International Airport to Myrtle Beach via Charlotte
- Ave. Duration
- 5h 45m
- When
- Every day
- Estimated price
- $90–490
Flights from Key West International Airport to Wilmington International Airport via Miami
- Ave. Duration
- 5h 39m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $120–700
Flights from Key West International Airport to Wilmington International Airport via Charlotte
- Ave. Duration
- 5h 17m
- When
- Every day
- Estimated price
- $140–750
Flights from Key West International Airport to Wilmington International Airport via Reagan Washington
- Ave. Duration
- 7h 13m
- When
- Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $180–900
- Website
- delta.com
Flights from Key West International Airport to Myrtle Beach via Atlanta
- Ave. Duration
- 5h 35m
- When
- Every day
- Estimated price
- $95–500
Flights from Key West International Airport to Wilmington International Airport via Atlanta
- Ave. Duration
- 5h 54m
- When
- Every day
- Estimated price
- $150–800
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Hollywood Amtrak Station to Kingstree Station
- Ave. Duration
- 13h 51m
- Frequency
- Once daily
- Estimated price
- $190–440
- Website
- https://www.amtrak.com/home.html
Train from Miami Amtrak Station to Charleston Amtrak Station
- Ave. Duration
- 13h 15m
- Frequency
- Once daily
- Estimated price
- $180–410
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 305-809-3700
- Website
- cityofkeywest-fl.gov
Bus from N Roosevelt & 4th Street to Big Pine Key - Auto Store / NAPA MM30
- Ave. Duration
- 53 min
- Frequency
- Every 3 hours
- Estimated price
- $2–4
- Schedules at
- https://www.cityofkeywest-fl.gov/595/Schedules-and-Route-Maps
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Big Pine Key to Miami Airport Station
- Ave. Duration
- 3h 30m
- Frequency
- 3 times a day
- Estimated price
- $22–45
- Website
- https://www.greyhound.com/
Bus from Wilmington Cape Fear Public Transit to Myrtle Beach Bus Station
- Ave. Duration
- 1h 35m
- Frequency
- Once daily
- Estimated price
- $13–25
- Website
- https://www.greyhound.com/
Bus from Charleston Bus Station to Myrtle Beach Bus Station
- Ave. Duration
- 2h 25m
- Frequency
- Once daily
- Estimated price
- $17–35
- Website
- https://www.greyhound.com/
- Phone
- +1 (305) 289-9997
- groups@keysshuttle.com
- Website
- keysshuttle.com
Shuttle from Key West, FL to Miami, FL - International Airport
- Ave. Duration
- 4h
- Frequency
- 3 times a day
- Estimated price
- $170–200
- Website
- https://www.keysshuttle.com
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