Rome2Rio

How to get fromKey West to Murrells Inletby plane, bus, train, car, or shuttle

Find Transport to Murrells Inlet

See all options

There are 6 ways to get from Key West to Murrells Inlet by plane, bus, train, car, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Myrtle Beach

    best
    1. Fly from Key West International Airport (EYW) to Myrtle Beach (MYR)plane plane EYW - MYR
    4h 51m
    $432–614

  2. Fly to Florence Regional Airport, drive

    cheapest
    1. Fly from Key West International Airport (EYW) to Florence Regional Airport (FLO)plane plane EYW - FLO
    2. Drive from Florence Regional Airport (FLO) to Murrells Inletcar car
    7h 5m
    $95–404

  3. Bus, train, drive

    1. Take the bus from N Roosevelt & 4th Street to Big Pine Key - Auto Store / NAPA MM30bus bus Lks
    2. Take the bus from Big Pine Key to Miami Airport Stationbus bus
    3. Take the train from Hollywood Amtrak Station to Kingstree Stationtrain train
    4. Drive from Kingstree Station to Murrells Inletcar car
    23h 3m
    $236–507

  4. Drive 820.6 mi

    1. Drive from Key West to Murrells Inletcar car 820.6 mi
    15h 1m
    $150–217

  5. Fly to Wilmington International Airport, bus

    1. Fly from Key West International Airport (EYW) to Wilmington International Airport (ILM)plane plane EYW - ILM
    2. Take the bus from Wilmington Cape Fear Public Transit to Myrtle Beach Bus Stationbus bus
    7h 59m
    $148–501

  6. Shuttle, train, bus

    1. Take a shuttle bus from Key West, FL to Miami, FL - International Airportshuttle bus
    2. Take the train from Miami Amtrak Station to Charleston Amtrak Stationtrain train
    3. Take the bus from Charleston Bus Station to Myrtle Beach Bus Stationbus bus
    23h 47m
    $418–704

Key West International Airport (EYW) to Myrtle Beach (MYR) flights

Calendar27Weekly Planes
Duration4h 49mAverage Duration
Ticket$73Cheapest Price
See schedules

Questions & Answers

What companies run services between Key West, FL, USA and Murrells Inlet, SC, USA?

American Airlines and Delta fly from Key West International Airport (EYW) to Myrtle Beach (MYR) 4 times a day.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Trips from Key West

Trips to Murrells Inlet

Popular routes