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How to get fromKey West to Murrells Inletby plane, bus, train, car, bus (Greyhound, Flixbus) or shuttle

Find Transport to Murrells Inlet

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There are 6 ways to get from Key West to Murrells Inlet by plane, bus, train, car, bus (Greyhound, Flixbus), or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Myrtle Beach

    best
    1. Fly from Key West International Airport (EYW) to Myrtle Beach (MYR)planeEYW - MYR
    4h 45m
    $132–504

  2. Bus, train, drive

    cheapest
    1. Take the bus from N Roosevelt & 4th Street to Big Pine Key - Auto Store / NAPA MM30busLks
    2. Take the bus from Big Pine Key to Miami Airport Stationbus
    3. Take the train from Hollywood Amtrak Station to Kingstree Amtrak Stationtrain
    4. Drive from Kingstree Amtrak Station to Murrells Inletcar
    23h 2m
    $103–282

  3. Bus

    1. Take the bus from N Roosevelt & 3rd Street to Big Pine Key - Auto Store / NAPA MM30busLks
    2. Take the bus from Big Pine Key to Miami Airport Stationbus
    3. Take the bus from Miami Airport Station to Jacksonvillebus
    4. Take the bus from Jacksonville to Florence Bus Stationbus
    5. Take the bus from Florence Bus Station to Myrtle Beach Bus Stationbus
    24h 38m
    $185–364

  4. Drive 820.5 mi

    1. Drive from Key West to Murrells Inletcar820.5 mi
    14h 52m
    $150–217

  5. Fly to Wilmington International Airport, bus

    1. Fly from Key West International Airport (EYW) to Wilmington International Airport (ILM)planeEYW - ILM
    2. Take the bus from Wilmington Cape Fear Public Transit to Myrtle Beach Bus Stationbus
    7h 17m
    $162–539

  6. Shuttle, train, bus

    1. Take a shuttle bus from Key West, FL to Miami, FL - International Airportshuttle
    2. Take the train from Miami Amtrak Station to Charleston Amtrak Stationtrain
    3. Take the bus from Charleston Bus Station to Myrtle Beach Bus Stationbus
    23h 42m
    $327–524

Key West International Airport (EYW) to Myrtle Beach (MYR) flights

Calendar43Weekly Planes
Duration5h 42mAverage Duration
Ticket$83Cheapest Price
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Questions & Answers

What companies run services between Key West, FL, USA and Murrells Inlet, SC, USA?

American Airlines and Delta fly from Key West International Airport (EYW) to Myrtle Beach (MYR) every 4 hours. Alternatively, you can take a bus from N Roosevelt & 3rd Street to Murrells Inlet via Big Pine Key - Auto Store / NAPA MM30, Big Pine Key, Miami Airport Station, Jacksonville, Florence Bus Station, and Myrtle Beach Bus Station in around 24h 38m.

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