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How to get fromKnoxville to Murrells Inletby plane, bus (Greyhound, Flixbus) or car

Find Transport to Murrells Inlet

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There are 3 ways to get from Knoxville to Murrells Inlet by plane, bus (Greyhound, Flixbus), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Mcghee Tyson Airport (TYS) to Myrtle Beach (MYR)plane plane TYS - MYR
    3h 45m
    $152–497
  2. Drive 409.1 mi

    cheapest
    1. Drive from Knoxville to Murrells Inletcar car 409.1 mi
    7h 49m
    $75–108
  3. Bus

    1. Take the bus from Knoxville to Nashvillebus bus Nyc
    2. Take the bus from Nashville Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Myrtle Beach Bus Stationbus bus
    19h 33m
    $263–424

Mcghee Tyson Airport (TYS) to Myrtle Beach (MYR) flights

Calendar71Weekly Planes
Duration4h 7mAverage Duration
Ticket$57Cheapest Price
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Questions & Answers

What companies run services between Knoxville, TN, USA and Murrells Inlet, SC, USA?

Delta, American Airlines, and Southwest Airlines fly from Mcghee Tyson Airport (TYS) to Myrtle Beach (MYR) every 3 hours. Alternatively, you can take a vehicle from Knoxville to Murrells Inlet via Knoxville, Nashville, Charlotte Pike & Lellyett St Eb, Central 5Th Ave - Bay 1, Central 4Th Ave - Bay 13, Fulton Station Outbound, Nashville Bus Station, Atlanta Bus Station, and Myrtle Beach Bus Station in around 19h 33m.

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