There are 3 ways to get from Knoxville to Murrells Inlet by plane, car, shuttle, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Mcghee Tyson Airport (TYS) to Myrtle Beach (MYR)plane TYS - MYR
3h 58m$162–577Drive 409.1 mi
cheapest- Drive from Knoxville to Murrells Inletcar 409.1 mi
7h 49m$75–108Drive, shuttle, bus
- Drive from Knoxville to Hot Springscar
- Take a shuttle bus from Hot Springs to Black Bear Resort
- Take a shuttle bus from Black Bear Resort to Boone
- Take the bus from ASU Peacock Hall Boone to Charlotte Airportbus
- Take the bus from Charlotte Bus Station to Wilmington Cape Fear Public Transitbus
- Take the bus from Wilmington Cape Fear Public Transit to Myrtle Beach Bus Stationbus
18h 57m$457–555
Mcghee Tyson Airport (TYS) to Myrtle Beach (MYR) flights
Questions & Answers
The cheapest way to get from Knoxville to Murrells Inlet is to drive which costs $70 - $110 and takes 7h 49m.
The fastest way to get from Knoxville to Murrells Inlet is to fly which takes 3h 58m and costs $160 - $600.
The distance between Knoxville and Murrells Inlet is 350 miles. The road distance is 411.5 miles.
It takes approximately 3h 58m to get from Knoxville to Murrells Inlet, including transfers.
Yes, the driving distance between Knoxville to Murrells Inlet is 411 miles. It takes approximately 7h 49m to drive from Knoxville to Murrells Inlet.
There are 3079+ hotels available in Murrells Inlet.
What companies run services between Knoxville, TN, USA and Murrells Inlet, SC, USA?
Delta, American Airlines, and Southwest Airlines fly from Mcghee Tyson Airport (TYS) to Myrtle Beach (MYR) every 4 hours.
- Website
- aa.com
Flights from Mcghee Tyson Airport to Myrtle Beach via Charlotte
- Ave. Duration
- 4h 38m
- When
- Every day
- Estimated price
- $65–460
Flights from Mcghee Tyson Airport to Myrtle Beach via Reagan Washington
- Ave. Duration
- 5h 34m
- When
- Monday to Friday
- Estimated price
- $100–600
- Website
- delta.com
Flights from Mcghee Tyson Airport to Myrtle Beach via Atlanta
- Ave. Duration
- 4h 3m
- When
- Every day
- Estimated price
- $75–490
- Website
- southwest.com
Flights from Mcghee Tyson Airport to Myrtle Beach via Nashville
- Ave. Duration
- 5h 45m
- When
- Thursday and Friday
- Estimated price
- $90–550
Flights from Mcghee Tyson Airport to Myrtle Beach via Baltimore
- Ave. Duration
- 7h 10m
- When
- Monday, Thursday, and Friday
- Estimated price
- $110–600
- Phone
- +1-423-725-5988
- Website
- blackbearresorttn.com
Shuttle from Hot Springs to Black Bear Resort
- Ave. Duration
- 1h 30m
- Frequency
- On demand
- Estimated price
- $136
- Website
- https://blackbearresorttn.com/Shuttle-Service.html
Shuttle from Black Bear Resort to Boone
- Ave. Duration
- 1h
- Frequency
- On demand
- Estimated price
- $86
- Website
- https://blackbearresorttn.com/Shuttle-Service.html
- Phone
- +1 828-327-2340
- reservations@hickoryhop.com
- Website
- hickoryhop.com
Bus from ASU Peacock Hall Boone to Charlotte Airport
- Ave. Duration
- 2h 30m
- Frequency
- Every 4 hours
- Estimated price
- $90–110
- Schedules at
- hickoryhop.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Charlotte Bus Station to Wilmington Cape Fear Public Transit
- Ave. Duration
- 6h 40m
- Frequency
- Once daily
- Estimated price
- $40–80
- Website
- https://www.greyhound.com/
Bus from Wilmington Cape Fear Public Transit to Myrtle Beach Bus Station
- Ave. Duration
- 1h 35m
- Frequency
- Once daily
- Estimated price
- $12–24
- Website
- https://www.greyhound.com/
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