There are 4 ways to get from Knoxville to Murrells Inlet by plane, car, shuttle, bus, or bus (Greyhound, Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Mcghee Tyson Airport (TYS) to Myrtle Beach (MYR)plane TYS - MYR
4h 9m$162–537Drive 409.1 mi
cheapest- Drive from Knoxville to Murrells Inletcar 409.1 mi
7h 49m$75–108Drive, shuttle, bus
- Drive from Knoxville to Hot Springscar
- Take a shuttle bus from Hot Springs to Black Bear Resort
- Take a shuttle bus from Black Bear Resort to Boone
- Take the bus from ASU Peacock Hall Boone to Charlotte Airportbus
- Take the bus from Charlotte Bus Station to Camdenbus
- Take the bus from Camden to Myrtle Beach Bus Stationbus
15h 38m$428–509Bus
- Take the bus from Knoxville to Nashvillebus Nyc
- Take the bus from Nashville Bus Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Myrtle Beach Bus Stationbus
19h 11m$253–409
Mcghee Tyson Airport (TYS) to Myrtle Beach (MYR) flights
Questions & Answers
The cheapest way to get from Knoxville to Murrells Inlet is to drive which costs $70 - $110 and takes 7h 49m.
The fastest way to get from Knoxville to Murrells Inlet is to fly which takes 4h 9m and costs $160 - $550.
The distance between Knoxville and Murrells Inlet is 350 miles. The road distance is 411.5 miles.
The best way to get from Knoxville to Murrells Inlet without a car is to bus which takes 19h 11m and costs $250 - $410.
It takes approximately 4h 9m to get from Knoxville to Murrells Inlet, including transfers.
The best way to get from Knoxville to Murrells Inlet is to fly which takes 4h 9m and costs $160 - $550. Alternatively, you can bus, which costs $250 - $410 and takes 19h 11m.
Yes, the driving distance between Knoxville to Murrells Inlet is 411 miles. It takes approximately 7h 49m to drive from Knoxville to Murrells Inlet.
There are 3186+ hotels available in Murrells Inlet.
What companies run services between Knoxville, TN, USA and Murrells Inlet, SC, USA?
Delta, American Airlines, and Southwest Airlines fly from Mcghee Tyson Airport (TYS) to Myrtle Beach (MYR) every 3 hours. Alternatively, you can take a vehicle from Knoxville to Murrells Inlet via Knoxville, Nashville, Charlotte Pike & Lellyett St Eb, Central 5Th Ave - Bay 1, Central 4Th Ave - Bay 13, Fulton Station Outbound, Nashville Bus Station, Atlanta Bus Station, and Myrtle Beach Bus Station in around 19h 11m.
- Website
- aa.com
Flights from Mcghee Tyson Airport to Myrtle Beach via Charlotte
- Ave. Duration
- 4h 1m
- When
- Every day
- Estimated price
- $65–420
Flights from Mcghee Tyson Airport to Myrtle Beach via Reagan Washington
- Ave. Duration
- 6h 29m
- When
- Every day
- Estimated price
- $110–600
- Website
- delta.com
Flights from Mcghee Tyson Airport to Myrtle Beach via Atlanta
- Ave. Duration
- 4h 4m
- When
- Every day
- Estimated price
- $80–460
- Website
- southwest.com
Flights from Mcghee Tyson Airport to Myrtle Beach via Nashville
- Ave. Duration
- 5h 45m
- When
- Saturday
- Estimated price
- $95–550
Flights from Mcghee Tyson Airport to Myrtle Beach via Baltimore
- Ave. Duration
- 5h 55m
- When
- Saturday
- Estimated price
- $110–600
- Phone
- +1-423-725-5988
- Website
- blackbearresorttn.com
Shuttle from Hot Springs to Black Bear Resort
- Ave. Duration
- 1h 30m
- Frequency
- On demand
- Estimated price
- $136
- Website
- https://blackbearresorttn.com/Shuttle-Service.html
Shuttle from Black Bear Resort to Boone
- Ave. Duration
- 1h
- Frequency
- On demand
- Estimated price
- $86
- Website
- https://blackbearresorttn.com/Shuttle-Service.html
- Phone
- +1 828-327-2340
- reservations@hickoryhop.com
- Website
- hickoryhop.com
Bus from ASU Peacock Hall Boone to Charlotte Airport
- Ave. Duration
- 2h 30m
- Frequency
- Every 4 hours
- Estimated price
- $90–110
- Schedules at
- hickoryhop.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Charlotte Bus Station to Camden
- Ave. Duration
- 1h 35m
- Frequency
- 4 times a day
- Estimated price
- $11–23
- Website
- https://www.greyhound.com/
Bus from Camden to Myrtle Beach Bus Station
- Ave. Duration
- 3h 20m
- Frequency
- 4 times a day
- Estimated price
- $17–35
- Website
- https://www.greyhound.com/
Bus from Nashville Bus Station to Atlanta Bus Station
- Ave. Duration
- 4h 30m
- Frequency
- Hourly
- Estimated price
- $35–75
- Website
- https://www.greyhound.com/
Bus from Atlanta Bus Station to Myrtle Beach Bus Station
- Ave. Duration
- 8h 40m
- Frequency
- Twice daily
- Estimated price
- $50–110
- Website
- https://www.greyhound.com/
- Phone
- +1 646-630-7186
- help@wandacoach.com
- Website
- wandacoach.com
Bus from Knoxville to Nashville
- Ave. Duration
- 3h
- Frequency
- Once daily
- Estimated price
- $40–60
- Website
- https://www.wandacoach.com
- Book at
- https://www.gotobus.com/wanda-travel/
- Adult One Way
- $40–60
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Nashville Bus Station to Atlanta Bus Station
- Ave. Duration
- 4h 10m
- Frequency
- 5 times a day
- Estimated price
- $30–55
- Schedules at
- flixbus.com
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