There are 3 ways to get from Isernia to Spoleto by train (Trenitalia), bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train
best- Take the train from Isernia to Roma TerminiRe
- Take the train from Roma Termini to Spoleto4150 / ...
4h 35m€20–64Bus
- Take the bus from Isernia to Roma, Autostazione Tiburtina
- Take the bus from Roma, Autostazione Tiburtina to Terni554
- Take the bus from Terni Bus Terminal to Spoleto - P. Vittoria
6h 17m€26–75Drive 243.2 km
- Drive from Isernia to Spoleto243.2 km
3h 34m€38–55
Isernia to Spoleto by train
Questions & Answers
The cheapest way to get from Isernia to Spoleto is to bus which costs €25 - €80 and takes 6h 17m.
The fastest way to get from Isernia to Spoleto is to drive which takes 3h 34m and costs €35 - €55.
No, there is no direct bus from Isernia to Spoleto. However, there are services departing from Isernia and arriving at Spoleto - P. Vittoria via Roma, Autostazione Tiburtina and Terni Bus Terminal. The journey, including transfers, takes approximately 6h 17m.
No, there is no direct train from Isernia to Spoleto. However, there are services departing from Isernia and arriving at Spoleto via Roma Termini. The journey, including transfers, takes approximately 4h 35m.
The distance between Isernia and Spoleto is 310 km. The road distance is 243.2 km.
The best way to get from Isernia to Spoleto without a car is to train which takes 4h 35m and costs €20 - €65.
It takes approximately 4h 35m to get from Isernia to Spoleto, including transfers.
Isernia to Spoleto bus services, operated by ATM Azienda di Trasporti Molisana S.p.A., depart from Isernia station.
Isernia to Spoleto train services, operated by Trenitalia S.p.A., depart from Isernia station.
The best way to get from Isernia to Spoleto is to train which takes 4h 35m and costs €20 - €65. Alternatively, you can bus, which costs €25 - €80 and takes 6h 17m.
What companies run services between Isernia, Italy and Spoleto, Italy?
You can take a train from Isernia to Spoleto via Roma Termini in around 4h 35m. Alternatively, you can take a bus from Isernia to Spoleto - P. Vittoria via Roma, Autostazione Tiburtina, Terni, and Terni Bus Terminal in around 6h 17m.
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Isernia to Roma Termini
- Ave. Duration
- 2h 22m
- Frequency
- 5 times a day
- Estimated price
- €11–35
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €24–35
Train from Roma Termini to Spoleto
- Ave. Duration
- 1h 29m
- Frequency
- Every 2 hours
- Estimated price
- €14–24
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Roma Termini to Spoleto
- Ave. Duration
- 1h 36m
- Frequency
- 3 times a day
- Estimated price
- €9–20
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Roma Termini to Spoleto
- Ave. Duration
- 1h 26m
- Frequency
- Once daily
- Estimated price
- €22–30
- Schedules at
- trenitalia.com
- Phone
- +39 0874 64744
- info@atm-molise.it
- Website
- atm-molise.it
Bus from Isernia to Roma, Autostazione Tiburtina
- Ave. Duration
- 2h 10m
- Frequency
- 3 times a day
- Estimated price
- €8–13
- Schedules at
- atm-molise.it
Rome2Rio's guide to FlixBus
Contact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Isernia to Roma, Autostazione Tiburtina
- Ave. Duration
- 2h 10m
- Frequency
- Once daily
- Estimated price
- €15–45
- Website
- https://www.flixbus.co.uk
Bus from Roma, Autostazione Tiburtina to Terni
- Ave. Duration
- 1h 25m
- Frequency
- Once daily
- Estimated price
- €10–21
- Website
- https://www.flixbus.co.uk
- Phone
- +39 06 44101
- fsbusitalia@pec.it
- Website
- fsbusitalia.it
Bus from Roma, Autostazione Tiburtina to Terni
- Ave. Duration
- 1h 35m
- Frequency
- Twice daily
- Estimated price
- €9–12
- Website
- https://www.fsbusitalia.it/eng.html
Bus from Terni Bus Terminal to Spoleto - P. Vittoria
- Ave. Duration
- 42 min
- Frequency
- Once daily
- Estimated price
- €8–11
- Website
- https://www.fsbusitalia.it/eng.html
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More Questions & Answers
Isernia to Spoleto bus services, operated by ATM Azienda di Trasporti Molisana S.p.A., arrive at Roma, Autostazione Tiburtina station.
Isernia to Spoleto train services, operated by Trenitalia S.p.A., arrive at Roma Termini station.
Yes, the driving distance between Isernia to Spoleto is 243 km. It takes approximately 3h 34m to drive from Isernia to Spoleto.
There are 1081+ hotels available in Spoleto.
























