There are 5 ways to get from Isernia to L'Aquila by train, bus, train (Trenitalia), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train, bus
best- Take the train from Isernia to Cassinotrain Re
- Take the bus from Cassino to L'Aquilabus 556 / ...
3h 45m€18–24Bus via Rome
cheapest- Take the bus from Isernia to Roma, Autostazione Tiburtinabus Campobasso / ...
- Take the bus from Roma, Autostazione Tiburtina to L'Aquilabus
4h 40m€17–45Train (Trenitalia)
- Take the train from Isernia to Roma Terminitrain Re
- Take the train from Roma Termini to Ternitrain
- Take the train from Terni to L'aquilatrain Re
7h 14m€30–54Drive 143.1 km
- Drive from Isernia to L'Aquilacar 143.1 km
2h 31m€22–32Bus
- Take the bus from Isernia to Chietibus 433
- Take the bus from Chieti Scalo Train Station to L'Aquila Amiternum Hotelbus MarinoBus 208 / ...
5h 44m€19–43
Isernia to L'Aquila by train and bus
Questions & Answers
The cheapest way to get from Isernia to L'Aquila is to train and bus which costs €17 - €24 and takes 3h 45m.
The fastest way to get from Isernia to L'Aquila is to drive which takes 2h 31m and costs €21 - €35.
No, there is no direct bus from Isernia to L'Aquila. However, there are services departing from Isernia and arriving at L'Aquila via Roma, Autostazione Tiburtina. The journey, including transfers, takes approximately 4h 40m.
No, there is no direct train from Isernia to L'Aquila. However, there are services departing from Isernia and arriving at L'aquila via Roma Termini and Terni. The journey, including transfers, takes approximately 7h 14m.
The distance between Isernia and L'Aquila is 185 km. The road distance is 143.1 km.
The best way to get from Isernia to L'Aquila without a car is to train and bus which takes 3h 45m and costs €17 - €24.
It takes approximately 3h 45m to get from Isernia to L'Aquila, including transfers.
Isernia to L'Aquila bus services, operated by FlixBus, depart from Isernia station.
Isernia to L'Aquila train services, operated by Trenitalia, depart from Isernia station.
The best way to get from Isernia to L'Aquila is to train which takes 7h 14m and costs €29 - €55. Alternatively, you can bus via Rome, which costs €17 - €45 and takes 4h 40m.
What companies run services between Isernia, Italy and L'Aquila, Italy?
You can take a train from Isernia to L'aquila via Roma Termini and Terni in around 7h 14m. Alternatively, you can take a bus from Isernia to L'Aquila via Roma, Autostazione Tiburtina in around 4h 40m.
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Isernia to Cassino
- Ave. Duration
- 40 min
- Frequency
- Every 4 hours
- Estimated price
- €6
- Website
- https://www.trenitalia.com/en.html
Train from Isernia to Roma Termini
- Ave. Duration
- 2h 25m
- Frequency
- 5 times a day
- Estimated price
- €11–17
- Website
- https://www.trenitalia.com/en.html
Train from Roma Termini to Terni
- Ave. Duration
- 1h 13m
- Frequency
- Hourly
- Estimated price
- €9–23
- Website
- https://www.trenitalia.com/en.html
Train from Terni to L'aquila
- Ave. Duration
- 1h 55m
- Frequency
- Every 4 hours
- Estimated price
- €9
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Roma Termini to Terni
- Ave. Duration
- 1h 10m
- Frequency
- 3 times a day
- Estimated price
- €10–17
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Roma Termini to Terni
- Ave. Duration
- 1h 3m
- Frequency
- Once daily
- Estimated price
- €19–28
- Schedules at
- trenitalia.com
Rome2Rio's guide to FlixBus
Contact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Cassino to L'Aquila
- Ave. Duration
- 2h 5m
- Frequency
- Twice daily
- Estimated price
- €12–18
- Website
- https://www.flixbus.co.uk
Bus from Isernia to Roma, Autostazione Tiburtina
- Ave. Duration
- 2h 10m
- Frequency
- Once daily
- Estimated price
- €8–35
- Website
- https://www.flixbus.co.uk
Bus from Isernia to Chieti
- Ave. Duration
- 2h 24m
- Frequency
- Twice daily
- Estimated price
- €7–23
- Website
- https://www.flixbus.co.uk
- Phone
- +39 0874 64744
- info@atm-molise.it
- Website
- atm-molise.it
Bus from Isernia to Roma, Autostazione Tiburtina
- Ave. Duration
- 2h 10m
- Frequency
- 3 times a day
- Estimated price
- €8–13
- Schedules at
- atm-molise.it
- Phone
- 085.43212
- info@tuabruzzo.it
- Website
- tuabruzzo.it
Bus from Roma, Autostazione Tiburtina to L'Aquila
- Ave. Duration
- 1h 35m
- Frequency
- Hourly
- Estimated price
- €9–14
- Schedules at
- tuabruzzo.it
- .
- €9–14
- Phone
- +39 080 3112335
- info@marinobus.it
- Website
- marinobus.it
Bus from Chieti Scalo Train Station to L'Aquila Amiternum Hotel
- Ave. Duration
- 2h 20m
- Frequency
- 4 times a week
- Estimated price
- €12–20
- Website
- https://marinobus.it/en/
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More Questions & Answers
Isernia to L'Aquila bus services, operated by FlixBus, arrive at Chieti station.
Isernia to L'Aquila train services, operated by Trenitalia, arrive at Roma Termini station.
Yes, the driving distance between Isernia to L'Aquila is 143 km. It takes approximately 2h 31m to drive from Isernia to L'Aquila.
Book your Isernia to L'Aquila bus tickets online with Omio.
There are 538+ hotels available in L'Aquila.

























