There are 7 ways to get from Mendrisio to Spoleto by train (Trenitalia), train, bus, car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train via Rome
best- Take the train from Mendrisio to Milano Centraletrain
- Take the train from Milano Centrale to Roma Tiburtinatrain
- Take the train from Roma Tiburtina to Spoletotrain
6h 38m€105–169Train, bus
cheapest- Take the train from Mendrisio to Milano Centraletrain
- Take the bus from Milano, San Donato M3 to Assisibus 529
- Take the train from Assisi to Spoletotrain Re
10h 13m€40–69Drive 565.3 km
- Drive from Mendrisio to Spoletocar 565.3 km
5h 45m€98–142Train to Milano Malpensa Airport, fly to Fiumicino International Airport, train
- Take the train from Mendrisio to Malpensa Aeroporto T1train
- Fly from Milano Malpensa Airport (MXP) to Fiumicino International Airport (FCO)plane MXP - FCO
- Take the train from Roma Termini to Spoletotrain
6h 16m€61–167Train
- Take the train from Mendrisio to Milano Centraletrain Re80
- Take the train from Milano Centrale to Spoletotrain Ic
8h 30m€77–167Train, train to Milan Linate Airport, fly to Fiumicino International Airport
- Take the train from Mendrisio to Seregnotrain
- Take the train from Seregno to Milano Forlaninitrain
- Fly from Milan Linate Airport (LIN) to Fiumicino International Airport (FCO)plane LIN - FCO
- Take the train from Roma Termini to Spoletotrain
6h 50m€64–212Fly Milan Linate Airport to Raffaello Sanzio Airport, train
- Fly from Milan Linate Airport (LIN) to Raffaello Sanzio Airport (AOI)plane LIN - AOI
- Take the train from Jesi to Spoletotrain
7h 40m€98–241
Mendrisio to Spoleto by train, subway, and bus
Questions & Answers
The cheapest way to get from Mendrisio to Spoleto is to train and bus which costs €40 - €70 and takes 10h 13m.
The fastest way to get from Mendrisio to Spoleto is to drive which takes 5h 45m and costs €95 - €150.
No, there is no direct train from Mendrisio to Spoleto. However, there are services departing from Mendrisio and arriving at Spoleto via Milano Centrale and Roma Tiburtina. The journey, including transfers, takes approximately 6h 38m.
The distance between Mendrisio and Spoleto is 735 km. The road distance is 565.3 km.
The best way to get from Mendrisio to Spoleto without a car is to train via Rome which takes 6h 38m and costs €100 - €170.
It takes approximately 6h 38m to get from Mendrisio to Spoleto, including transfers.
Mendrisio to Spoleto train services, operated by Swiss Federal Railways (SBB CFF FFS), depart from Mendrisio station.
Mendrisio to Spoleto train services, operated by Swiss Federal Railways (SBB CFF FFS), arrive at Milano Centrale station.
Yes, the driving distance between Mendrisio to Spoleto is 565 km. It takes approximately 5h 45m to drive from Mendrisio to Spoleto.
There are 1123+ hotels available in Spoleto.
What companies run services between Mendrisio, Switzerland and Spoleto, Italy?
You can take a train from Mendrisio to Spoleto via Milano Centrale and Roma Tiburtina in around 6h 38m.
- Website
- ita-airways.com
Flights from Milan Linate Airport to Fiumicino International Airport
- Ave. Duration
- 1h 10m
- When
- Every day
- Estimated price
- €45–150
- Website
- aeroitalia.com
Flights from Milano Malpensa Airport to Fiumicino International Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- €50–170
Flights from Milan Linate Airport to Fiumicino International Airport via Olbia
- Ave. Duration
- 3h
- When
- Every day
- Estimated price
- €130–350
- Website
- flexflight.dk
Flights from Milano Malpensa Airport to Fiumicino International Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- €50–170
Flights from Milan Linate Airport to Fiumicino International Airport via Olbia
- Ave. Duration
- 3h
- When
- Every day
- Estimated price
- €130–350
- Website
- dat.dk
Flights from Milan Linate Airport to Raffaello Sanzio Airport
- Ave. Duration
- 1h 20m
- When
- Monday to Friday
- Estimated price
- €110–150
- Website
- neosair.it
Flights from Milano Malpensa Airport to Fiumicino International Airport
- Ave. Duration
- 1h 20m
- When
- Wednesday
- Estimated price
- €110–370
- Phone
- +41 848 446 688
- Website
- sbb.ch
Train from Mendrisio to Milano Centrale
- Ave. Duration
- 59 min
- Frequency
- Hourly
- Estimated price
- €26–50
- Website
- https://www.sbb.ch/en
Train from Mendrisio to Malpensa Aeroporto T1
- Ave. Duration
- 1h 8m
- Frequency
- Hourly
- Estimated price
- €27–50
- Website
- https://www.sbb.ch/en
Train from Mendrisio to Seregno
- Ave. Duration
- 40 min
- Frequency
- Hourly
- Estimated price
- €20–40
- Website
- https://www.sbb.ch/en
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Milano Centrale to Roma Tiburtina
- Ave. Duration
- 3h 4m
- Frequency
- Hourly
- Estimated price
- €70–95
- Website
- https://www.italotreno.it/en
- Smart Economy
- €70–95
- Smart Flex
- €75–95
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Roma Tiburtina to Spoleto
- Ave. Duration
- 1h 21m
- Frequency
- Hourly
- Estimated price
- €8–12
- Website
- https://www.trenitalia.com/en.html
Train from Assisi to Spoleto
- Ave. Duration
- 36 min
- Frequency
- Every 4 hours
- Estimated price
- €4–7
- Website
- https://www.trenitalia.com/en.html
Train from Roma Termini to Spoleto
- Ave. Duration
- 1h 29m
- Frequency
- Hourly
- Estimated price
- €8–13
- Website
- https://www.trenitalia.com/en.html
Train from Jesi to Spoleto
- Ave. Duration
- 1h 38m
- Frequency
- 5 times a day
- Estimated price
- €8–13
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Roma Tiburtina to Spoleto
- Ave. Duration
- 1h 26m
- Frequency
- 3 times a day
- Estimated price
- €11–27
- Website
- https://www.trenitalia.com/en.html
Train from Assisi to Spoleto
- Ave. Duration
- 32 min
- Frequency
- Twice daily
- Estimated price
- €4–10
- Website
- https://www.trenitalia.com/en.html
Train from Roma Termini to Spoleto
- Ave. Duration
- 1h 36m
- Frequency
- 3 times a day
- Estimated price
- €12–28
- Website
- https://www.trenitalia.com/en.html
Train from Milano Centrale to Spoleto
- Ave. Duration
- 6h 31m
- Frequency
- Once daily
- Estimated price
- €50–120
- Website
- https://www.trenitalia.com/en.html
Train from Jesi to Spoleto
- Ave. Duration
- 1h 54m
- Frequency
- Twice daily
- Estimated price
- €12–29
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 02 7249 4494
- my-link@trenord.it
- Website
- trenord.it
Train from Mendrisio to Milano Centrale
- Ave. Duration
- 59 min
- Frequency
- Hourly
- Estimated price
- €5–7
- Website
- https://www.trenord.it/en/
Train from Mendrisio to Malpensa Aeroporto T1
- Ave. Duration
- 1h 8m
- Frequency
- Hourly
- Estimated price
- €5–7
- Website
- https://www.trenord.it/en/
Train from Mendrisio to Seregno
- Ave. Duration
- 40 min
- Frequency
- Hourly
- Estimated price
- €3–5
- Website
- https://www.trenord.it/en/
Train from Seregno to Milano Forlanini
- Ave. Duration
- 36 min
- Frequency
- Hourly
- Estimated price
- €3–4
- Website
- https://www.trenord.it/en/
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Roma Termini to Spoleto
- Ave. Duration
- 1h 26m
- Frequency
- Once daily
- Estimated price
- €17–35
- Schedules at
- trenitalia.com
Train from Jesi to Spoleto
- Ave. Duration
- 1h 31m
- Frequency
- Once daily
- Estimated price
- €18–35
- Schedules at
- trenitalia.com
Rome2Rio's guide to FlixBus
Contact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Milano, San Donato M3 to Assisi
- Ave. Duration
- 6h 15m
- Frequency
- 5 times a week
- Estimated price
- €29–50
- Website
- https://www.flixbus.co.uk
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