Rome2Rio

How to get fromIowa to Mobileby plane, bus (Greyhound), bus, train, car or bus (Greyhound, Flixbus)

Find Transport to Mobile

See all options

There are 10 ways to get from Iowa to Mobile by plane, bus (Greyhound), bus, train, car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Des Moines to Mobile Regional Airport

    best
    1. Fly from Des Moines (DSM) to Mobile Regional Airport (MOB)plane plane DSM - MOB
    7h 47m
    $138–671

  2. Fly Quad City International Airport to Mobile Regional Airport

    cheapest
    1. Fly from Quad City International Airport (MLI) to Mobile Regional Airport (MOB)plane plane MLI - MOB
    11h 9m
    $87–442

  3. Bus (Greyhound)

    1. Take the bus from Des Moines to Indianapolis Union Stationbus bus
    2. Take the bus from Indianapolis Union Station to Montgomery Intermodal Centerbus bus
    3. Take the bus from Montgomery Intermodal Center to Mobile Bus Stationbus bus
    29h 9m
    $213–425

  4. Bus, train

    1. Take the bus from Des Moines to Champaign Intermodal Trans Ctrbus bus
    2. Take the train from Champaign-Urbana to New Orleans Union Passenger Terminaltrain train
    3. Take the bus from New Orleans Bus Station to Mobile Bus Stationbus bus
    30h 28m
    $302–680

  5. Drive 955.7 mi

    1. Drive from Des Moines to Mobilecar car 955.7 mi
    18h 8m
    $175–252

  6. Fly Des Moines to Pensacola International Airport, bus

    1. Fly from Des Moines (DSM) to Pensacola International Airport (PNS)plane plane DSM - PNS
    2. Take the bus from Pensacola Airport to Mobile Bus Stationbus bus
    8h 17m
    $148–691

  7. Fly Omaha to Mobile Regional Airport

    1. Fly from Omaha (OMA) to Mobile Regional Airport (MOB)plane plane OMA - MOB
    10h 45m
    $153–753

  8. Fly Quad City International Airport to Pensacola International Airport, bus

    1. Fly from Quad City International Airport (MLI) to Pensacola International Airport (PNS)plane plane MLI - PNS
    2. Take the bus from Pensacola Airport to Mobile Bus Stationbus bus
    10h 9m
    $92–442

  9. Bus to The Eastern Iowa Airport, fly to Mobile Regional Airport

    1. Take the bus from Court St Transportation Center to GTC Bay 9bus bus
    2. Fly from The Eastern Iowa Airport (CID) to Mobile Regional Airport (MOB)plane plane CID - MOB
    12h 12m

  10. Bus via St. Louis

    1. Take the bus from Des Moines to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to New Orleans Bus Stationbus bus
    3. Take the bus from New Orleans Bus Station to Mobile Bus Stationbus bus
    31h 4m
    $217–430

Des Moines (DSM) to Mobile Regional Airport (MOB) flights

Calendar59Weekly Planes
Duration6h 47mAverage Duration
Ticket$127Cheapest Price
See schedules

Questions & Answers

What companies run services between Iowa, USA and Mobile, AL, USA?

Delta, American Airlines, and United Airlines fly from Des Moines (DSM) to Mobile Regional Airport (MOB) every 4 hours. Alternatively, you can take a vehicle from Des Moines to Water NB at St Louis St via Des Moines, Indianapolis Union Station, Montgomery Intermodal Center, Mobile Bus Station, and Govt EB at Greyhound Bus Station in around 29h 9m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Trips from Iowa

Trips to Mobile

Popular routes