There are 4 ways to get from Iowa to Indianapolis by plane, bus (Greyhound), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Des Moines
best- Fly from Des Moines (DSM) to Indianapolis (IND)plane DSM - IND
4h 52m$115–623Fly from Quad City International Airport
cheapest- Fly from Quad City International Airport (MLI) to Indianapolis (IND)plane MLI - IND
6h 40m$59–384Bus (Greyhound)
- Take the bus from Des Moines to Indianapolis Union Stationbus Greyhound US0157S
9h 45m$89–160Drive 465.7 mi
- Drive from Des Moines to Indianapoliscar 465.7 mi
7h 53m$85–123
Des Moines (DSM) to Indianapolis (IND) flights
Questions & Answers
The cheapest way to get from Iowa to Indianapolis is to drive which costs $85 - $130 and takes 7h 53m.
The fastest way to get from Iowa to Indianapolis is to fly which takes 4h 52m and costs $110 - $650.
The distance between Iowa and Indianapolis is 429 miles. The road distance is 468.4 miles.
The best way to get from Iowa to Indianapolis without a car is to bus which takes 9h 45m and costs $85 - $160.
It takes approximately 4h 52m to get from Iowa to Indianapolis, including transfers.
The best way to get from Iowa to Indianapolis is to fly which takes 4h 52m and costs $110 - $650. Alternatively, you can bus, which costs $85 - $160 and takes 9h 45m.
Indianapolis is 1h ahead of Iowa. It is currently 1:05 PM in Iowa and 2:05 PM in Indianapolis.
Yes, the driving distance between Iowa to Indianapolis is 468 miles. It takes approximately 7h 53m to drive from Iowa to Indianapolis.
There are 925+ hotels available in Indianapolis.
What companies run services between Iowa, USA and Indianapolis, IN, USA?
United Airlines, American Airlines, and two other airlines fly from Des Moines (DSM) to Indianapolis (IND) hourly. Alternatively, Greyhound USA operates a bus from Des Moines to Indianapolis Union Station once daily. Tickets cost $80–150 and the journey takes 9h 40m.
- Website
- united.com
Flights from Des Moines to Indianapolis via Chicago O'Hare
- Ave. Duration
- 4h 4m
- When
- Every day
- Estimated price
- $95–600
Flights from Quad City International Airport to Indianapolis via Chicago O'Hare
- Ave. Duration
- 3h 34m
- When
- Every day
- Estimated price
- $55–380
- Website
- aa.com
Flights from Des Moines to Indianapolis via Chicago O'Hare
- Ave. Duration
- 4h 55m
- When
- Every day
- Estimated price
- $95–600
Flights from Des Moines to Indianapolis via Charlotte
- Ave. Duration
- 5h 2m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $180–900
Flights from Quad City International Airport to Indianapolis via Chicago O'Hare
- Ave. Duration
- 4h 42m
- When
- Every day
- Estimated price
- $55–380
Flights from Quad City International Airport to Indianapolis via Charlotte
- Ave. Duration
- 6h 20m
- When
- Every day
- Estimated price
- $120–600
Flights from Quad City International Airport to Indianapolis via Dallas/Ft.Worth
- Ave. Duration
- 6h 45m
- When
- Every day
- Estimated price
- $140–700
- Website
- delta.com
Flights from Des Moines to Indianapolis via Minneapolis
- Ave. Duration
- 4h 38m
- When
- Every day
- Estimated price
- $120–700
Flights from Des Moines to Indianapolis via Atlanta
- Ave. Duration
- 5h 10m
- When
- Every day
- Estimated price
- $170–850
Flights from Des Moines to Indianapolis via Detroit
- Ave. Duration
- 5h 48m
- When
- Every day
- Estimated price
- $120–700
Flights from Quad City International Airport to Indianapolis via Atlanta
- Ave. Duration
- 6h 5m
- When
- Every day
- Estimated price
- $110–600
- Website
- southwest.com
Flights from Des Moines to Indianapolis via Chicago Midway
- Ave. Duration
- 4h 55m
- When
- Every day
- Estimated price
- $95–600
- Website
- allegiantair.com
Flights from Quad City International Airport to Indianapolis via St. Petersburg
- Ave. Duration
- 7h 25m
- When
- Sunday
- Estimated price
- $180–800
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Des Moines to Indianapolis Union Station
- Ave. Duration
- 9h 40m
- Frequency
- Once daily
- Estimated price
- $80–150
- Website
- https://www.greyhound.com/
Want to know more about travelling around United States
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