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How to get fromIowa to Indianapolisby plane, bus or car

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There are 6 ways to get from Iowa to Indianapolis by plane, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Des Moines

    best
    1. Fly from Des Moines (DSM) to Indianapolis (IND)planeDSM - IND
    5h 6m
    $130–673
  2. Fly from Quad City International Airport

    cheapest
    1. Fly from Quad City International Airport (MLI) to Indianapolis (IND)planeMLI - IND
    6h 45m
    $59–354
  3. Bus

    1. Take the bus from Des Moines to Indianapolis Union StationbusDenver
    9h 30m
    $80–160
  4. Drive 465.7 mi

    1. Drive from Des Moines to Indianapoliscar465.7 mi
    7h 49m
    $85–123
  5. Fly from The Eastern Iowa Airport

    1. Fly from The Eastern Iowa Airport (CID) to Indianapolis (IND)planeCID - IND
    6h 24m
    $84–402
  6. Fly from Omaha

    1. Fly from Omaha (OMA) to Indianapolis (IND)planeOMA - IND
    7h 18m
    $125–705

Iowa to Indianapolis by bus

Calendar7Weekly Buses
Duration9h 30mAverage Duration
Ticket$80Cheapest Price
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Questions & Answers

What companies run services between Iowa, USA and Indianapolis, IN, USA?

United Airlines, American Airlines, and two other airlines fly from Des Moines (DSM) to Indianapolis (IND) hourly. Alternatively, Burlington Trailways operates a bus from Des Moines to Indianapolis Union Station once daily. Tickets cost $80–160 and the journey takes 9h 30m.

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