There are 6 ways to get from Iowa to Indianapolis by plane, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Des Moines
best- Fly from Des Moines (DSM) to Indianapolis (IND)DSM - IND
5h 6m$130–673Fly from Quad City International Airport
cheapest- Fly from Quad City International Airport (MLI) to Indianapolis (IND)MLI - IND
6h 45m$59–354Bus
- Take the bus from Des Moines to Indianapolis Union StationDenver
9h 30m$80–160Drive 465.7 mi
- Drive from Des Moines to Indianapolis465.7 mi
7h 49m$85–123Fly from The Eastern Iowa Airport
- Fly from The Eastern Iowa Airport (CID) to Indianapolis (IND)CID - IND
6h 24m$84–402Fly from Omaha
- Fly from Omaha (OMA) to Indianapolis (IND)OMA - IND
7h 18m$125–705
Iowa to Indianapolis by bus
Questions & Answers
The cheapest way to get from Iowa to Indianapolis is to drive which costs $85 - $130 and takes 7h 49m.
The fastest way to get from Iowa to Indianapolis is to fly which takes 5h 6m and costs $130 - $700.
Yes, there is a direct bus departing from Des Moines and arriving at Indianapolis Union Station station. Services depart once daily, and operate every day. The journey takes approximately 9h 30m.
The distance between Iowa and Indianapolis is 429 miles. The road distance is 468.4 miles.
The best way to get from Iowa to Indianapolis without a car is to bus which takes 9h 30m and costs $80 - $160.
It takes approximately 5h 6m to get from Iowa to Indianapolis, including transfers.
Iowa to Indianapolis bus services, operated by Burlington Trailways, depart from Des Moines station.
The best way to get from Iowa to Indianapolis is to fly which takes 5h 6m and costs $130 - $700. Alternatively, you can bus, which costs $80 - $160 and takes 9h 30m.
Iowa to Indianapolis bus services, operated by Burlington Trailways, arrive at Indianapolis Union Station.
Indianapolis is 1h ahead of Iowa. It is currently 8:58 PM in Iowa and 9:58 PM in Indianapolis.
What companies run services between Iowa, USA and Indianapolis, IN, USA?
United Airlines, American Airlines, and two other airlines fly from Des Moines (DSM) to Indianapolis (IND) hourly. Alternatively, Burlington Trailways operates a bus from Des Moines to Indianapolis Union Station once daily. Tickets cost $80–160 and the journey takes 9h 30m.
- Website
- delta.com
Flights from Des Moines to Indianapolis via Detroit
- Ave. Duration
- 4h 47m
- When
- Every day
- Estimated price
- $140–750
Flights from Des Moines to Indianapolis via Minneapolis
- Ave. Duration
- 6h 22m
- When
- Every day
- Estimated price
- $140–750
Flights from Des Moines to Indianapolis via Atlanta
- Ave. Duration
- 5h 7m
- When
- Monday, Tuesday, Friday, Saturday, and Sunday
- Estimated price
- $190–900
Flights from The Eastern Iowa Airport to Indianapolis via Minneapolis
- Ave. Duration
- 5h 23m
- When
- Every day
- Estimated price
- $80–430
Flights from The Eastern Iowa Airport to Indianapolis via Atlanta
- Ave. Duration
- 4h 54m
- When
- Monday, Tuesday, Friday, and Sunday
- Estimated price
- $110–550
Flights from Quad City International Airport to Indianapolis via Atlanta
- Ave. Duration
- 5h 32m
- When
- Every day
- Estimated price
- $100–500
Flights from Omaha to Indianapolis via Minneapolis
- Ave. Duration
- 5h 22m
- When
- Every day
- Estimated price
- $140–800
Flights from Omaha to Indianapolis via Atlanta
- Ave. Duration
- 5h 5m
- When
- Every day
- Estimated price
- $200–950
Flights from Omaha to Indianapolis via Detroit
- Ave. Duration
- 5h 47m
- When
- Every day
- Estimated price
- $160–800
- Website
- aa.com
Flights from Des Moines to Indianapolis via Chicago O'Hare
- Ave. Duration
- 4h 52m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $110–650
Flights from Des Moines to Indianapolis via Charlotte
- Ave. Duration
- 5h 25m
- When
- Every day
- Estimated price
- $190–900
Flights from The Eastern Iowa Airport to Indianapolis via Chicago O'Hare
- Ave. Duration
- 5h 22m
- When
- Every day
- Estimated price
- $60–360
Flights from The Eastern Iowa Airport to Indianapolis via Reagan Washington
- Ave. Duration
- 5h
- When
- Monday, Tuesday, Thursday, Friday, and Sunday
- Estimated price
- $120–550
Flights from The Eastern Iowa Airport to Indianapolis via Dallas/Ft.Worth
- Ave. Duration
- 8h 3m
- When
- Every day
- Estimated price
- $130–600
Flights from Quad City International Airport to Indianapolis via Chicago O'Hare
- Ave. Duration
- 5h 25m
- When
- Every day
- Estimated price
- $55–350
Flights from Quad City International Airport to Indianapolis via Charlotte
- Ave. Duration
- 5h 37m
- When
- Monday, Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $100–550
Flights from Quad City International Airport to Indianapolis via Dallas/Ft.Worth
- Ave. Duration
- 6h 27m
- When
- Every day
- Estimated price
- $130–600
Flights from Omaha to Indianapolis via Chicago O'Hare
- Ave. Duration
- 5h 29m
- When
- Every day
- Estimated price
- $120–700
Flights from Omaha to Indianapolis via Dallas/Ft.Worth
- Ave. Duration
- 5h 27m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $210–1,000
- Website
- united.com
Flights from Des Moines to Indianapolis via Chicago O'Hare
- Ave. Duration
- 4h 5m
- When
- Every day
- Estimated price
- $110–650
Flights from The Eastern Iowa Airport to Indianapolis via Chicago O'Hare
- Ave. Duration
- 4h 28m
- When
- Every day
- Estimated price
- $60–360
Flights from The Eastern Iowa Airport to Indianapolis via Denver
- Ave. Duration
- 5h 57m
- When
- Every day
- Estimated price
- $140–650
Flights from Quad City International Airport to Indianapolis via Chicago O'Hare
- Ave. Duration
- 3h 51m
- When
- Every day
- Estimated price
- $55–350
Flights from Omaha to Indianapolis via Chicago O'Hare
- Ave. Duration
- 5h 12m
- When
- Every day
- Estimated price
- $120–700
- Website
- southwest.com
Flights from Des Moines to Indianapolis via Chicago Midway
- Ave. Duration
- 5h 15m
- When
- Monday and Friday
- Estimated price
- $110–650
Flights from Omaha to Indianapolis via Chicago Midway
- Ave. Duration
- 3h 37m
- When
- Monday, Tuesday, Friday, Saturday, and Sunday
- Estimated price
- $120–700
Flights from Omaha to Indianapolis via Dallas
- Ave. Duration
- 7h 5m
- When
- Saturday
- Estimated price
- $210–1,000
- Phone
- +1 (319) 753-2864
- info@burlingtontrailways.com
- Website
- burlingtontrailways.com
Bus from Des Moines to Indianapolis Union Station
- Ave. Duration
- 9h 30m
- Frequency
- Once daily
- Estimated price
- $80–160
- Website
- https://burlingtontrailways.com
- Saver Fares
- $80–120
- Flexible Fares
- $110–160
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More Questions & Answers
Yes, the driving distance between Iowa to Indianapolis is 468 miles. It takes approximately 7h 49m to drive from Iowa to Indianapolis.
There are 848+ hotels available in Indianapolis.



