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How to get fromIowa to Indianapolisby plane, bus (Greyhound, Flixbus), car, bus or train

Find Transport to Indianapolis

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There are 5 ways to get from Iowa to Indianapolis by plane, bus (Greyhound, Flixbus), car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Des Moines

    best
    1. Fly from Des Moines (DSM) to Indianapolis (IND)plane plane DSM - IND
    5h
    $130–723

  2. Fly from Quad City International Airport

    cheapest
    1. Fly from Quad City International Airport (MLI) to Indianapolis (IND)plane plane MLI - IND
    7h 4m
    $59–374

  3. Bus

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus Greyhound US0123 / ...
    2. Take the bus from Chicago Bus Station to Indianapolisbus bus FlixBus N2640 / ...
    12h
    $84–180

  4. Drive 465.7 mi

    1. Drive from Des Moines to Indianapoliscar car 465.7 mi
    7h 53m
    $85–123

  5. Bus, train

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus Greyhound US0123 / ...
    2. Take the train from Chicago Union Station to Indianapolistrain train Cardinal
    13h 13m
    $79–175

Des Moines (DSM) to Indianapolis (IND) flights

Calendar77Weekly Planes
Duration5h 11mAverage Duration
Ticket$113Cheapest Price
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Questions & Answers

What companies run services between Iowa, USA and Indianapolis, IN, USA?

United Airlines, Delta, and two other airlines fly from Des Moines (DSM) to Indianapolis (IND) every 2 hours. Alternatively, you can take a vehicle from Des Moines to Indianapolis via Des Moines and Chicago Bus Station in around 12h.

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Need to know: Greyhound

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