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How to get fromIowa to Indianaby plane, train, bus (Greyhound, Flixbus), car or bus

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There are 7 ways to get from Iowa to Indiana by plane, train, bus (Greyhound, Flixbus), car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Des Moines to Chicago O'Hare International Airport, train

    best
    1. Fly from Des Moines (DSM) to Chicago O'Hare International Airport (ORD)plane plane DSM - ORD
    2. Take the train from Van Buren St. to Gary Metro Centertrain train
    3h 45m
    $87–455

  2. Line 60 bus to Quad City International Airport, fly to Chicago O'Hare International Airport, train

    cheapest
    1. Take the bus from District to SouthPark Mall Shelterbus bus
    2. Fly from Quad City International Airport (MLI) to Chicago O'Hare International Airport (ORD)plane plane MLI - ORD
    3. Take the train from Van Buren St. to Gary Metro Centertrain train
    5h 26m
    $41–236

  3. Bus

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus Greyhound US0123 / ...
    2. Take the bus from Chicago Bus Station to Indianapolisbus bus FlixBus N2640 / ...
    12h
    $84–180

  4. Drive 465.7 mi

    1. Drive from Des Moines to Indianapoliscar car 465.7 mi
    7h 53m
    $85–123

  5. Fly Waterloo Municipal Airport to Chicago O'Hare International Airport, train

    1. Fly from Waterloo Municipal Airport (ALO) to Chicago O'Hare International Airport (ORD)plane plane ALO - ORD
    2. Take the train from Van Buren St. to Gary Metro Centertrain train
    3h 34m
    $63–276

  6. Line 41 bus to Omaha, fly to Chicago Midway International Airport, train

    1. Take the bus from 8th & Broadway NE to 11th & Dodge NEbus bus
    2. Fly from Omaha (OMA) to Chicago Midway International Airport (MDW)plane plane OMA - MDW
    3. Take the train from Van Buren St. to Gary Metro Centertrain train
    6h 4m
    $112–667

  7. Bus, train

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus Greyhound US0123 / ...
    2. Take the train from Chicago Union Station to Indianapolistrain train Cardinal
    13h 13m
    $79–175

Des Moines (DSM) to Chicago O'Hare International Airport (ORD) flights

Calendar50Weekly Planes
Duration1h 38mAverage Duration
Ticket$64Cheapest Price
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Questions & Answers

What companies run services between Iowa, USA and Indiana, USA?

You can take a vehicle from Des Moines to Indianapolis via Des Moines and Chicago Bus Station in around 12h.

Airlines
Train operators
Bus operators

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