There are 6 ways to get from Des Moines to Indiana by plane, bus, car, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to South Bend
best- Fly from Des Moines (DSM) to South Bend (SBN)plane DSM - SBN
3h 58m$142–738Bus
cheapest- Take the bus from Des Moines to Indianapolis Union Stationbus Denver
9h 30m$80–160Drive 465.7 mi
- Drive from Des Moines to Indianapoliscar 465.7 mi
7h 53m$85–123Fly to Chicago O'Hare International Airport, train
- Fly from Des Moines (DSM) to Chicago O'Hare International Airport (ORD)plane DSM - ORD
- Take the train from Van Buren St. to Gary Metro Centertrain
3h 46m$92–455Fly to Chicago Midway International Airport, train
- Fly from Des Moines (DSM) to Chicago Midway International Airport (MDW)plane DSM - MDW
- Take the train from Van Buren St. to Gary Metro Centertrain
3h 25m$117–635Fly to Purdue University Airport
- Fly from Des Moines (DSM) to Purdue University Airport (LAF)plane DSM - LAF
4h 53m$115–623
Des Moines to Indiana by bus
Questions & Answers
The cheapest way to get from Des Moines to Indiana is to drive which costs $85 - $130 and takes 7h 53m.
The fastest way to get from Des Moines to Indiana is to fly and train which takes 3h 25m and costs $110 - $650.
Yes, there is a direct bus departing from Des Moines and arriving at Indianapolis Union Station station. Services depart once daily, and operate every day. The journey takes approximately 9h 30m.
The distance between Des Moines and Indiana is 392 miles. The road distance is 468.4 miles.
The best way to get from Des Moines to Indiana without a car is to bus which takes 9h 30m and costs $80 - $160.
It takes approximately 3h 58m to get from Des Moines to Indiana, including transfers.
Des Moines to Indiana bus services, operated by Burlington Trailways, depart from Des Moines station.
The best way to get from Des Moines to Indiana is to fly which takes 3h 58m and costs $140 - $750. Alternatively, you can bus, which costs $80 - $160 and takes 9h 30m.
Des Moines to Indiana bus services, operated by Burlington Trailways, arrive at Indianapolis Union Station.
Indiana is 1h ahead of Des Moines. It is currently 2:15 AM in Des Moines and 3:15 AM in Indiana.
What companies run services between Des Moines, IA, USA and Indiana, USA?
United Airlines, Delta, and American Airlines fly from Des Moines (DSM) to South Bend (SBN) every 4 hours. Alternatively, Burlington Trailways operates a bus from Des Moines to Indianapolis Union Station once daily. Tickets cost $80–160 and the journey takes 9h 30m.
- Website
- united.com
Flights from Des Moines to South Bend via Chicago O'Hare International Airport
- Ave. Duration
- 4h 4m
- When
- Every day
- Estimated price
- $110–700
Flights from Des Moines to Chicago O'Hare International Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- $65–420
Flights from Des Moines to Purdue University Airport via Chicago O'Hare International Airport
- Ave. Duration
- 5h 32m
- When
- Every day
- Estimated price
- $95–600
- Website
- delta.com
Flights from Des Moines to South Bend via Minneapolis
- Ave. Duration
- 5h 14m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $140–800
Flights from Des Moines to South Bend via Detroit
- Ave. Duration
- 7h 5m
- When
- Every day
- Estimated price
- $150–850
Flights from Des Moines to South Bend via Atlanta
- Ave. Duration
- 7h 42m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $230–1,100
- Website
- aa.com
Flights from Des Moines to South Bend via Charlotte
- Ave. Duration
- 5h 48m
- When
- Saturday
- Estimated price
- $230–1,100
Flights from Des Moines to Chicago O'Hare International Airport
- Ave. Duration
- 1h 42m
- When
- Every day
- Estimated price
- $65–420
- Website
- southwest.com
Flights from Des Moines to Chicago Midway International Airport
- Ave. Duration
- 1h 20m
- When
- Monday, Thursday, and Friday
- Estimated price
- $90–600
Flights from Des Moines to Chicago Midway International Airport via St. Louis
- Ave. Duration
- 3h 15m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $110–650
- Phone
- +1 219-926-5744
- Website
- mysouthshoreline.com
Train from Van Buren St. to Gary Metro Center
- Ave. Duration
- 46 min
- Frequency
- Every 30 minutes
- Estimated price
- $7–9
- Schedules at
- mysouthshoreline.com
- Adults 14-64
- $7–9
- Phone
- +1 (319) 753-2864
- info@burlingtontrailways.com
- Website
- burlingtontrailways.com
Bus from Des Moines to Indianapolis Union Station
- Ave. Duration
- 9h 30m
- Frequency
- Once daily
- Estimated price
- $80–160
- Schedules at
- burlingtontrailways.com
- Book at
- burlingtontrailways.com
- Saver Fares
- $80–120
- Flexible Fares
- $110–160
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More Questions & Answers
Yes, the driving distance between Des Moines to Indiana is 468 miles. It takes approximately 7h 53m to drive from Des Moines to Indiana.
There are 730+ hotels available in Indiana.



