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How to get fromDes Moines to Indianaby plane, bus (Greyhound), car, or train

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There are 6 ways to get from Des Moines to Indiana by plane, bus (Greyhound), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Indianapolis

    best
    1. Fly from Des Moines (DSM) to Indianapolis (IND)plane plane DSM - IND
    5h 7m
    $141–775
  2. Bus (Greyhound)

    cheapest
    1. Take the bus from Des Moines to Indianapolis Union Stationbus bus Greyhound US0157S
    9h 25m
    $75–120
  3. Drive  465.7 mi

    1. Drive from Des Moines to Indianapoliscar car 465.7 mi
    7h 54m
    $85–123
  4. Fly to Chicago O'Hare International Airport, train

    1. Fly from Des Moines (DSM) to Chicago O'Hare International Airport (ORD)plane plane DSM - ORD
    2. Take the train from Van Buren St. to Gary Metro Centertrain train
    3h 44m
    $84–398
  5. Fly to Chicago Midway International Airport, train

    1. Fly from Des Moines (DSM) to Chicago Midway International Airport (MDW)plane plane DSM - MDW
    2. Take the train from Van Buren St. to Gary Metro Centertrain train
    3h 22m
    $99–498
  6. Fly to South Bend, train

    1. Fly from Des Moines (DSM) to South Bend (SBN)plane plane DSM - SBN
    2. Take the train from South Bend Airport to Gary Metro Centertrain train
    6h 8m
    $140–786

Des Moines to Indiana by bus (Greyhound)

Calendar7Weekly Buses
Duration9h 25mAverage Duration
Ticket$75Cheapest Price
See schedules

Comparing Your Travel Options

What companies run services between Des Moines, IA, USA and Indiana, USA?

United Airlines, Delta, and two other airlines fly from Des Moines (DSM) to Indianapolis (IND) hourly. Alternatively, Greyhound USA operates a bus from Des Moines to Indianapolis Union Station once daily. Tickets cost $75–120 and the journey takes 9h 25m.

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